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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00005351-protein ID=TCONS_00005351-protein|Name=TCONS_00005351-protein|organism=Clytia hemisphaerica|type=polypeptide|length=698bp
MGFIRIKLIEAEAGSEVWKECESQGKTWDPFVGIHIKEAVDVPGQGIQLV
QKKKTIYPDWNRCFDTHLYEGRMITLVVMNKNDSGSVTGDATVGVHFLAD
QCKKNGGLNTSTVSLDLRPHGKLSVQVRHFSETADDPNSGALDGKTLANK
SELQARRGAVRKAKVHEIKGHQLIAKFFRQPAFCSVCNQFMWGFNKQGYQ
CSSCAMAAHKKCHDKILFQCTQSAADSQGTMKMKERFNINMPHRFIGKTY
LSPSFCDHCGSMLYGLFRQGLKCEACNMNVHHKCKEKVPNLCGINQILFS
EAMKSIENKKKRDSSISEDDGDEVTTMEDESALYESVWEDIKPAPPARTS
SIRPGTRKKRYDISDFKFLKVLGKGTFGKVILAEVPSENNAVYAVKALKK
DVVLEDDDVECTLVERRVLALSTRHPYLTHLMATFQNESHLFFVMEYLNG
GDLMFHIQKEGKFIENRARFYGAEIICGLQFLHSHDIVYRDLKLDNVLLD
REGHIKIADFGMCKEEMTEGLKTSTFCGTPDYIAPEILKGHRYDSATDWW
SFGVLLYEMLIGQSPFAGEDEDDLFASICRDRVFFPKWISEAAISVLNGL
LERNISLRLGYSWGTKPHIRKHPFFSPIDWNKLEKREIKPPFKPEVKANN
AVNNFDPDFTMEAPKLTPTDADLLKSMDQVQFKGFSFINPAFHVKKIM Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
| GO:0035556 | intracellular signal transduction |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0005524 | ATP binding |
| GO:0004672 | protein kinase activity |
| GO:0004697 | protein kinase C activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004697 |
protein kinase C activity |
| molecular_function |
GO:0004674 |
protein serine/threonine kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR020454 | Diacylglycerol/phorbol-ester binding | PRINTS | PR00008 | DAGPEDOMAIN | coord: 168..182
score: 37.36
coord: 184..193
score: 45.74
coord: 281..293
score: 46.76
coord: 269..280
score: 44.8 |
| IPR000961 | AGC-kinase, C-terminal | SMART | SM00133 | pkinase_C_6 | coord: 626..689
e-value: 2.0E-18
score: 77.2 |
| IPR000961 | AGC-kinase, C-terminal | PROSITE | PS51285 | AGC_KINASE_CTER | coord: 626..697
score: 16.773 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 366..625
e-value: 1.1E-91
score: 320.6 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 367..625
e-value: 1.7E-62
score: 211.1 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 366..625
score: 47.622 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 171..220
e-value: 6.0E-14
score: 62.3
coord: 243..292
e-value: 4.0E-17
score: 72.9 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 171..221
e-value: 8.3E-13
score: 47.9
coord: 243..294
e-value: 3.4E-16
score: 58.7 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 243..292 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 242..292
score: 16.119 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 170..220
score: 14.761 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 171..220
e-value: 7.42061E-15
score: 69.0579 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 243..292
e-value: 1.10603E-17
score: 77.1471 |
| IPR000008 | C2 domain | GENE3D | 2.60.40.150 | | coord: 1..132
e-value: 1.4E-4
score: 21.4 |
| IPR000008 | C2 domain | SUPERFAMILY | 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | coord: 1..130 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 359..438
e-value: 3.8E-17
score: 61.8 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 158..222
e-value: 2.9E-22
score: 77.8 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 439..645
e-value: 2.4E-65
score: 218.8 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 237..302
e-value: 3.8E-21
score: 74.2 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 310..329 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 148..222 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 233..295 |
| IPR017892 | Protein kinase, C-terminal | PFAM | PF00433 | Pkinase_C | coord: 652..687
e-value: 1.0E-7
score: 32.4 |
| IPR014376 | Protein kinase C, delta/epsilon/eta/theta types | PIRSF | PIRSF000551 | PKC_delta | coord: 1..697
e-value: 8.3E-290
score: 961.0 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 487..499 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 372..396 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 362..687 |
Blast
BLAST of TCONS_00005351-protein vs. Swiss-Prot (Human)
Match: KPCD (Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2) HSP 1 Score: 702.59 bits (1812), Expect = 0.000e+0 Identity = 358/702 (51.00%), Postives = 466/702 (66.38%), Query Frame = 0
Query: 3 FIRIKLIEAEAGSEVWKECESQGKTWDPFVGIHIKEAVDVPGQGIQLVQKKKTIYPDWNRCFDTHLYEGRMITLVVMNKNDSGSVTGDATVGVHFLADQCKKNGGLNTSTVSLDLRPHGKLSVQVRHFSETADDPNSGALDGKTLANKSELQARRGAVRKAKVHEIKGHQLIAKFFRQPAFCSVCNQFMWGFNKQGYQCSSCAMAAHKKCHDKILFQCTQSAADSQGTMKMKERFNINMPHRFIGKTYLSPSFCDHCGSMLYGLFRQGLKCEACNMNVHHKCKEKVPNLCGINQILFSEAMKSIENKKKRD------------SSISEDDGDEVTTMEDESALYESVWEDIKPAPPARTSSIRPGTRKKRYDISDFKFLKVLGKGTFGKVILAEVPSENNAVYAVKALKKDVVLEDDDVECTLVERRVLALSTRHPYLTHLMATFQNESHLFFVMEYLNGGDLMFHIQKEGKFIENRARFYGAEIICGLQFLHSHDIVYRDLKLDNVLLDREGHIKIADFGMCKEEMTEGLKTSTFCGTPDYIAPEILKGHRYDSATDWWSFGVLLYEMLIGQSPFAGEDEDDLFASICRDRVFFPKWISEAAISVLNGLLERNISLRLGYSWGTKPHIRKHPFFSPIDWNKLEKREIKPPFKPEVKANNAVNNFDPDFTMEAPKLTPTDADLLKSMDQVQFKGFSFINPAF 692
F+RI E GS +++ + PF + +KEA+ +G LVQKK T+YP+W FD H+YEGR+I +V+M + + TVGV LA++CKKN G + LDL+P K+ + V++F E D S + + K RRGA+++AK+H IK H+ IA FF QP FCSVC F+WG NKQGY+C C A HKKC DKI+ +CT +AA+S+ T+ KERFNI+MPHRF Y+SP+FCDHCGS+L+GL +QGLKCE C MNVHHKC+EKV NLCGINQ L +EA+ + + R + G M+D S Y +WE G+ K +I++F F KVLGKG+FGKV+L E+ +A+KALKKDVVL DDDVECT+VE+RVL L+ +P+LTHL+ TFQ + HLFFVME+LNGGDLM+HIQ +G+F RA FY AEI+CGLQFLHS I+YRDLKLDNVLLDR+GHIKIADFGMCKE + + STFCGTPDYIAPEIL+G +Y + DWWSFGVLLYEMLIGQSPF G+DED+LF SI D +P+WI++ + +L L ER + RLG + +I+ HPFF I+W LEKR ++PPF+P+VK+ +NFD +F E +L+ +D +L+ SMDQ F GFSF+NP F
Sbjct: 4 FLRIAFNSYELGS-----LQAEDEANQPFCAVKMKEALSTE-RGKTLVQKKPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEEP--VSEVTVGVSVLAERCKKNNG--KAEFWLDLQPQAKVLMSVQYFLEDVDCKQSMRSEDEA---KFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASRRSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWE---------------GSSK--CNINNFIFHKVLGKGSFGKVLLGELKGRGE-YFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVT----GNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKF 670
The following BLAST results are available for this feature:
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