TCONS_00006149-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00006149-protein
Unique Name	TCONS_00006149-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1080

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00006149-protein ID=TCONS_00006149-protein|Name=TCONS_00006149-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1080bp
MAIRKCFRFFLILLFIININLIHCLTPIRLGVAIPWSGKNWDAGPRFASG
ISIAVEKINADPTLLPGYNISFIWKDSQCDEKRTLGVIADMLKDDQFPVN
ALIGPACSDGCRSGSYLADNWNVPMISYGCAASFFSVPQKFPNFARTVGV
YSKSGHIFVNLMKTYKWTRIAILTPSSGIWSSIMNGVRNDIEAEDGLQVP
FFQNFNKDSVSDSFLKRQLEDAKEQAHIFLLGGYKATILKVMKQAKKIGL
LRPGYAFISYELLIDKCVLPNKTEAEDCELLEGMLDISLFVPQNEAYQKF
ANLVRKKMAEEPFNRFMAPEEPVEIYAAMLHDAALLYAHALNKTLNMNGS
ILDGRLIINNTLNYTFEGASGTVVIDHVGDRASALVVKNVHNGRYQRTAN
FFVTEKRLQVLNNTVVWPGKTTAIPLGRPECDFDNRLCPPTEPWVYVVAG
VLTFIILLLGVIFFIVHHRRKLFEQALMSQTWRVKFSDIQFNQKHHQGRM
NHAGSICFTKQQQQQMNNNQNGGVNTVSAMMPLLQNHSHGSQQSIESIVH
ETQVFTRIGLFQGNYVAIKQLFKSSVQLTRELLVELKEVSELQHQNVNSF
IGACVDSPNICILTQYCNKGSLQDVLFNEDLKLDWMFQVSIASDIARGMQ
YIHNGASIGVHGRLKSTNCVIDSRWTCKITDIGLFKFKDGQAVDEEVGID
HEYDALLWTAPEHLDNMKEERSKEGDVYSYGIILQEIITRGSPYSMYENL
SAKEILDRVKKCSNPRFRPVVPEDYGHPEYHDLMSQCWEEAPTSRPRFDE
IMKALKKLNGGKNINIVDNMIKMMEKYTDHLEELVAERTKQLEDEKAKTD
ELLYRMLPRTVAEQLKHGEAVSAETFDMVTIFFSDIVGFTKLAAESTPMQ
VVDLLNDLYTCFDQIVDQHHVYKVETIGDAYMVVSGLPERNGNRHAGEIA
RMSLDLLSATTTFVVRHKKEYRIQLRIGIHSGSCVAGVVGLKMPRYCLFG
DTVNYASRMESSGLALRIHVSPECHEVLTELGGYHLIERGPVSMKGKGTI
VTYFLAGYDGFDKTLPDLQFAAGLEEHSFK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_003509	XLOC_003509	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00006149	TCONS_00006149	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001170	ANPR/GUC
IPR001054	A/G_cyclase
IPR001828	ANF_lig-bd_rcpt
IPR011645	HNOB_dom_associated
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR018297	A/G_cyclase_CS
IPR000719	Prot_kinase_dom
IPR011009	Kinase-like_dom
IPR029787	Nucleotide_cyclase
IPR028082	Peripla_BP_I

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction
GO:0006182	cGMP biosynthetic process
GO:0006468	protein phosphorylation

Vocabulary: **Molecular Function**
Term	Definition
GO:0016849	phosphorus-oxygen lyase activity
GO:0004383	guanylate cyclase activity
GO:0004672	protein kinase activity
GO:0005524	ATP binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006182	cGMP biosynthetic process
biological_process	GO:0009190	cyclic nucleotide biosynthetic process
biological_process	GO:0035556	intracellular signal transduction
biological_process	GO:0006468	protein phosphorylation
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004383	guanylate cyclase activity
molecular_function	GO:0016849	phosphorus-oxygen lyase activity
molecular_function	GO:0004672	protein kinase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 817..844
None	No IPR available	GENE3D	3.40.50.2300		coord: 25..383 e-value: 6.8E-51 score: 172.8
None	No IPR available	GENE3D	1.10.510.10		coord: 606..872 e-value: 6.0E-42 score: 143.3
None	No IPR available	GENE3D	3.30.200.20		coord: 468..605 e-value: 8.8E-9 score: 34.9
None	No IPR available	CDD	cd07302	CHD	coord: 879..1055 e-value: 3.40242E-66 score: 220.143
None	No IPR available	CDD	cd06352	PBP1_NPR_GC_like	coord: 29..411 e-value: 1.08635E-76 score: 257.24
IPR001170	Adenylyl cyclase class-4/guanylyl cyclase	PRINTS	PR00255	NATPEPTIDER	coord: 103..121 score: 26.64 coord: 368..385 score: 40.62 coord: 330..348 score: 44.08 coord: 448..470 score: 17.93
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	SMART	SM00044	cyc_6	coord: 844..1038 e-value: 1.2E-107 score: 373.6
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	PFAM	PF00211	Guanylate_cyc	coord: 872..1056 e-value: 9.3E-67 score: 224.1
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	GENE3D	3.30.70.1230		coord: 873..1061 e-value: 5.2E-76 score: 254.0
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	PROSITE	PS50125	GUANYLATE_CYCLASE_2	coord: 880..1010 score: 52.121
IPR001828	Receptor, ligand binding region	PFAM	PF01094	ANF_receptor	coord: 50..391 e-value: 3.0E-60 score: 204.1
IPR011645	Haem NO binding associated	PFAM	PF07701	HNOBA	coord: 819..865 e-value: 8.9E-7 score: 28.5
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 564..805 e-value: 1.7E-43 score: 148.7
IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site	PROSITE	PS00452	GUANYLATE_CYCLASE_1	coord: 987..1010
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 531..808 score: 27.496
IPR011009	Protein kinase-like domain	SUPERFAMILY	56112	Protein kinase-like (PK-like)	coord: 562..815
IPR029787	Nucleotide cyclase	SUPERFAMILY	55073	Nucleotide cyclase	coord: 866..1055
IPR028082	Periplasmic binding protein-like I	SUPERFAMILY	53822	Periplasmic binding protein-like I	coord: 27..433

Blast

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BLAST of TCONS_00006149-protein vs. Swiss-Prot (Human)
Match: ANPRA (Atrial natriuretic peptide receptor 1 OS=Homo sapiens GN=NPR1 PE=1 SV=1)

HSP 1 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 408/1069 (38.17%), Postives = 575/1069 (53.79%), Query Frame = 0

Query:   32 VAIPWSGKNWDAGPRFASGISIAVEKINADPTLLPGYNISFIWKDSQCDEKRTLGVIADM--------LKDDQFPVNALIGPACSDGCRSGSYLADNWNVPMISYGCAASFFSVPQKFPNFARTVGVYSKSGHIFVNLMKTYKWTRIAILTPSSGIWSS-----IMNGVRNDIEAEDGLQVPFFQNFNKDSVSDSFLKRQLEDAKEQAHIFLLGGYKATILKVMKQAKKIGLLRPGYAFISYELLID-----KCVLPNKT----EAEDCELLEGMLDISLFV---PQNEAYQKFANLVRKKMAEEPFNRFMAPEEPVEIYAAMLHDAALLYAHALNKTLNMNGSILDGRLIINNTLNYTFEGASGTVVIDHVGDRAS--ALVVKNVHNGRYQRTANFFVTEKRLQVLNNTVVWPGKTTAIPLGRP-----ECDFDNR--LCPP---TEPWVYVVAGVLTFIILLLGVIFFIVHHRRKLFEQALMSQTWRVKFSDIQFNQKHHQGRMNHAGSICFTKQQQQQMNNNQNGGVNTVSAMMPLLQNHSHGSQQSIESIVHETQVFTRIGLFQGNYVAIKQLFKSSVQLTRELLVELKEVSELQHQNVNSFIGACVDSPNICILTQYCNKGSLQDVLFNEDLKLDWMFQVSIASDIARGMQYIHNGASIGVHGRLKSTNCVIDSRWTCKITDIGLFKFKDGQAVDEEVGIDHEYDALLWTAPEHLDNMKE--ERSKEGDVYSYGIILQEIITRGSPYSMYE-NLSAKEILDRVKKCSNPRFRPVVPEDYGHPEYHDLMSQCWEEAPTSRPRFDEIMKALKKLNGGKNINIVDNMIKMMEKYTDHLEELVAERTKQLEDEKAKTDELLYRMLPRTVAEQLKHGEAVSAETFDMVTIFFSDIVGFTKLAAESTPMQVVDLLNDLYTCFDQIVDQHHVYKVETIGDAYMVVSGLPERNGNRHAGEIARMSLDLLSATTTFVVRHKKEYRIQLRIGIHSGSCVAGVVGLKMPRYCLFGDTVNYASRMESSGLALRIHVSPECHEVLTELGGYHLIERGPVSMKGKGTIVTYFLAGYDG 1060
             + PWS   W    R    + +A+ ++ A P LLPG+ +  +   S+      LGV +D         LK +  P    +GP C            +W VP+++ G  A  F V  ++    R    Y+K G     L +   W R A++  +           ++ G+   +     + V   + F +D +S     R L     +  +  +         +M  A + GL    Y F   ++        +   P +     + +D    +      +     P N  Y +F   + K +A E FN F   +  V    A  HD  LLY  A+ +TL   G++ DG  I     N +F+G +G + ID  GDR +  +L   +  NG ++   N+  T + L      V   G+    PLG P     +C FDN    C     +   V  + G L+ + +L+ V FFI  +R+   E+ L S+ WRV++ D++ +       +  AGS                    T+S      +  ++GS  + E    + QVF +   ++GN VA+K++ +  ++LTR++L ELK + ++Q++++  F+GAC D PNICILT+YC +GSLQD+L NE + LDWMF+ S+ +DI +GM ++HNGA I  HG LKS+NCV+D R+  KITD GL  F+D   +D E G    Y   LWTAPE L         S+ GDVYS+GIILQEI  R   + +   +LS KEI++RV +   P FRP +       E   LM +CW E P  RP F +I   L+K N   + NI+DN++  ME+Y ++LEELV ERT+   +EK K + LLY++LP +VAEQLK GE V AE FD VTI+FSDIVGFT L+AESTPMQVV LLNDLYTCFD ++D   VYKVETIGDAYMVVSGLP RNG  HA E+ARM+L LL A  +F +RH+ + +++LRIGIH+G   AGVVGLKMPRYCLFGDTVN ASRMES+G AL+IH+S E   VL E GG+ L  RG V MKGKG + TY+L G  G
Sbjct:   46 TSYPWS---W---ARVGPAVELALAQVKARPDLLPGWTVRTVLGSSE----NALGVCSDTAAPLAAVDLKWEHNPA-VFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLE-FAEDDLSH--YTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQL-KHLAYEQFN-FTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQEL------VAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILI-VSFFI--YRKMQLEKELASELWRVRWEDVEPSSLERH--LRSAGSRL------------------TLSG-----RGSNYGSLLTTEG---QFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGA-ICSHGNLKSSNCVVDGRFVLKITDYGLESFRD---LDPEQG-HTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERG 1056

The following BLAST results are available for this feature:

BLAST of TCONS_00006149-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00006149-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ANPRA	0.000e+0	38.17	Atrial natriuretic peptide receptor 1 OS=Homo sapi...	[more]

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TCONS_00006149-protein (polypeptide) - C. hemisphaerica