TCONS_00006587-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00006587-protein
Unique NameTCONS_00006587-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length791

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006587-protein ID=TCONS_00006587-protein|Name=TCONS_00006587-protein|organism=Clytia hemisphaerica|type=polypeptide|length=791bp
MNLPKLSTTIVAWLAIMVCCANSENIWIKVITTRSEFYEPGLEIARKHIM
KTNLLGKHKLQFNYVRPGTTLILFLKQLAAFNMKHFLTIGPASSRDITLI
SPLVTENSMIQYNLNGLVNDFEDVNMYPYLFNFCVLFSGYERALTTFLHH
HNWTRVAFIYISDTTKFSDTYYRSATSTEVHVRERGINVERLEKFSMFDD
STRANVPQWNRILKSTRDDNDLRIYVYFFNVLAMRYTLCELYKLGMYGPK
YVHIVFHSKWFVYYKGFARGRTNCTVEQENIVLKNFVFMNRASKRDDDIL
TVANLTVGQINSEVKASFNKKFPKHIYPNEKLDSESLYYYDALWSFAKSI
NHISKKHPRFVDNFDNWEKNTTRLSIMTDAMSNLDFEGVTAKIKFHQKGN
IRRLNSNIDFKKYDGNSSTTKTGKVNTTLMDVIGDDGNYVDRFRTEWEFP
IPLDAPKIVESTKEYGETVLIIIWLFAGAGILLCLIFLTINIYYRQVDFI
KLSSPNINNLICVGGIVTYISIFLGGLDTTIVDVEKVPLFCNISIVVLSV
GFTLTFGSLFSKTWRIYRIFTKKNSIRSVVIRDTHLFGVVMVLLLIDFAM
FVCFLAIAPYHLQAQVIDEKLIPSEDIILKTIINRCTSDHQNWFLGAMFF
YKGLLMLFGLFLAYETKNIKVESINDSKYIGFAVYNVSLFATLGSIVFTS
LYNTEHYRASYIVFCVCIIQSTTVTLCLIFGPKVWNILKDYKDPNFHNGR
PVIPGQHYTNSNSHSMKSGSQSQSDANKEMESGKSEYSSEK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003725XLOC_003725Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006587TCONS_00006587Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002456GPCR_3_GABA_rcpt_B1
IPR000337GPCR_3
IPR017978GPCR_3_C
IPR001828ANF_lig-bd_rcpt
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004965G-protein coupled GABA receptor activity
GO:0004930G-protein coupled receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004965 G-protein coupled GABA receptor activity
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR01176GABABRECEPTRcoord: 590..615
score: 21.33
coord: 626..646
score: 28.57
coord: 560..577
score: 38.89
coord: 339..351
score: 44.76
coord: 675..698
score: 37.12
coord: 236..259
score: 32.58
coord: 469..492
score: 28.41
coord: 508..529
score: 45.04
coord: 541..560
score: 40.0
NoneNo IPR availableGENE3D3.40.50.2300coord: 142..438
e-value: 4.4E-17
score: 62.0
NoneNo IPR availableGENE3D1.20.1250.20coord: 467..737
e-value: 1.7E-6
score: 27.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 757..791
IPR002456GPCR family 3, gamma-aminobutyric acid receptor, type B1PRINTSPR01177GABAB1RECPTRcoord: 679..701
score: 30.43
coord: 335..353
score: 36.84
coord: 468..493
score: 30.77
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 549..570
score: 35.37
coord: 651..674
score: 23.96
coord: 140..156
score: 26.65
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 481..735
e-value: 2.9E-48
score: 164.6
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 476..738
score: 26.635
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 41..400
e-value: 5.9E-24
score: 84.7
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 20..405

Blast
BLAST of TCONS_00006587-protein vs. Swiss-Prot (Human)
Match: GABR2 (Gamma-aminobutyric acid type B receptor subunit 2 OS=Homo sapiens GN=GABBR2 PE=1 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 2.443e-70
Identity = 198/714 (27.73%), Postives = 329/714 (46.08%), Query Frame = 0
Query:   40 PGLEIARKHIMKTNLLGKHKLQFNYVRPGTTLILFLKQLAAF------NMKHFLTIGPASSRDITLISPLVTENSMIQYNLNGLVNDFEDVNMYPYLFNFCVLFSGYERALTTFLHHHNWTRVAFIYISDTTKFSDTYYRSATSTEVHVRERGINVERLEKFSMFDDSTRANVPQWN-RILKSTRDDNDLRIYVYFFNVLAMRYTLCELYKLGMYGPKYVHIV---FHSKWFVYYKGFARGRTNCTVEQENIVLKNFVFMNRASKRDDDILTVANLTVGQINSEVKASFNKKFPKHIYPNEKLDSESLYYYDALWSFAKSIN------HISKKHPRFVDNFDNWEKNTTRLSIMTDAMSNLDFEGVTAKIKFHQKGNIRRLNSNIDFKKYDGNSSTTKTGKVNTTL--MDVIGDDGNYVDRFRTEWEFPIPLDAPKIVESTKEYGETVLIIIWLFAGAGILLCLIFLTINIYYRQVDFIKLSSPNINNLICVGGIVTYISIFLGGLDTTIVDVEKVPLFCNISIVVLSVGFTLTFGSLFSKTWRIYRIFTKKNSIRSVVIRDTHLFGVVMVLLLIDFAMFVCFLAIAPYHLQAQVIDEKLIPS-EDIILKTIINRCTSDHQNWFLGAMFFYKGLLMLFGLFLAYETKNIKVESINDSKYIGFAVYNVSLFATLGSIVFTSLYNTEHYRASYIVFCVCIIQSTTVTLCLIFGPKV 734
            P +E+A + I   +LL  +   F  +R   T     K L AF         H +  G       ++I+  +   +++Q +         D   YPY F      +    A+   L H+ W RV  +   D  +FS+            VR     V   E   + D  + +N P  + + LK     ND+RI +  F+        C  Y+  MYG KY  I+   +   W+      A   + C  +     ++ ++ ++        I T++  T  Q   E     +   P   +          Y YD +W  AK++       H S +H R  D F+  +    R  I+ +AM+  +F GVT ++ F    N  R+ + I F ++  +S   K G+ N     +++I D        R +   P P D   I+E  ++    +  I+      G+++   FL  NI  R    IK+SSP +NNLI +GG+++Y SIFL GLD + V  +     C +   +L+VG+T  FG++F+KTWR++ IF K   ++  +I+D  L  +V  +LLID  + +C+ A+ P     +    +  P+  DI ++ ++  C + H   +LG ++ YKGLLMLFG FLA+ET+N+ + ++NDSKYIG +VYNV +   +G+ V  S    +     + +  + II  +T+TLCL+F PK+
Sbjct:   79 PAVELAIEQIRNESLLRPY---FLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTL-TQDVQRFSE------------VRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKG----NDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANS-SRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHG---------YAYDGIWVIAKTLQRAMETLHASSRHQRIQD-FNYTDHTLGR--IILNAMNETNFFGVTGQVVFR---NGERMGT-IKFTQFQ-DSREVKVGEYNAVADTLEIINDT------IRFQGSEP-PKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIF-KNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAV--SFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKL 744          
The following BLAST results are available for this feature:
BLAST of TCONS_00006587-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GABR22.443e-7027.73Gamma-aminobutyric acid type B receptor subunit 2 ... [more]
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