TCONS_00006955-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00006955-protein
Unique NameTCONS_00006955-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length462

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006955-protein ID=TCONS_00006955-protein|Name=TCONS_00006955-protein|organism=Clytia hemisphaerica|type=polypeptide|length=462bp
MGHRFDSKEINFFRKNILKQYDTSQRSLPWRTIAKECQDENKRAYSVWVS
EIMLQQTQVATVIDYYNRWIKKWPTVEDLAEATIEEVNTQWSGLGYYSRG
KRLHQGAQEVMNKLNGQIPRTSTALQKKLPGVGPYTAGAIASIAYNEPCG
VVDGNVIRVLCRLRTIGANSNSNQVQELLWELAKEVVDPDRPGDFNQALM
EFGALTCTPKAPKCGDCPLKDICNAYKMTQAKEKKKKTEDKQIYTCPDIE
DAGACCYCLPSSVPWEPSLGVMNYPRKEKKKPPASEQFATIILKQNGKYL
LTKRPETGLLAGLWEFPSDQIQPKTTENNSNSETSISEAQLRQKCRDYLK
TTFCVEIAAKDLIPCGQVVHVFSHRRHTYHVFKADLKKKDVGINESEKMR
WIAKDGFDDIGITTAIRKILALSEGSTQLKGKRPNTGNNDAAKRTLTPNK
KQKRMDEFFKKK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003886XLOC_003886Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006955TCONS_00006955Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003651Endonuclease3_FeS-loop_motif
IPR003265HhH-GPD_domain
IPR000445HhH_motif
IPR023170HTH_base_excis_C
IPR029119MutY_C
IPR004036Endonuclease-III-like_CS2
IPR011257DNA_glycosylase
IPR015797NUDIX_hydrolase_dom-like
Vocabulary: Molecular Function
TermDefinition
GO:00515394 iron, 4 sulfur cluster binding
GO:0003677DNA binding
GO:0003824catalytic activity
GO:0016787hydrolase activity
Vocabulary: Biological Process
TermDefinition
GO:0006284base-excision repair
GO:0006281DNA repair
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006284 base-excision repair
biological_process GO:0006281 DNA repair
molecular_function GO:0051539 4 iron, 4 sulfur cluster binding
molecular_function GO:0003824 catalytic activity
molecular_function GO:0003677 DNA binding
molecular_function GO:0016787 hydrolase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003651Endonuclease III-like, iron-sulphur cluster loop motifSMARTSM00525ccc3coord: 206..226
e-value: 3.2E-5
score: 33.4
IPR003651Endonuclease III-like, iron-sulphur cluster loop motifPFAMPF10576EndIII_4Fe-2Scoord: 207..223
e-value: 1.4E-4
score: 22.0
IPR003265HhH-GPD domainSMARTSM00478endo3endcoord: 53..205
e-value: 5.4E-48
score: 175.4
IPR003265HhH-GPD domainPFAMPF00730HhH-GPDcoord: 49..184
e-value: 8.6E-21
score: 74.3
IPR003265HhH-GPD domainCDDcd00056ENDO3ccoord: 45..203
e-value: 5.13978E-49
score: 165.492
IPR000445Helix-hairpin-helix motifPFAMPF00633HHHcoord: 114..143
e-value: 3.8E-6
score: 26.4
NoneNo IPR availableGENE3D1.10.340.30coord: 27..132
e-value: 8.2E-30
score: 103.1
NoneNo IPR availableGENE3D3.90.79.10coord: 279..430
e-value: 8.9E-18
score: 64.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 427..462
IPR023170Helix-turn-helix, base-excision DNA repair, C-terminalGENE3D1.10.1670.10coord: 133..240
e-value: 3.0E-41
score: 139.6
IPR029119MutY, C-terminalPFAMPF14815NUDIX_4coord: 291..421
e-value: 1.9E-21
score: 76.0
IPR029119MutY, C-terminalCDDcd03431DNA_Glycosylase_Ccoord: 286..422
e-value: 6.77513E-26
score: 100.489
IPR004036Endonuclease III-like, conserved site-2PROSITEPS01155ENDONUCLEASE_III_2coord: 116..146
IPR011257DNA glycosylaseSUPERFAMILY48150DNA-glycosylasecoord: 8..227
IPR015797NUDIX hydrolase domain-likeSUPERFAMILY55811Nudixcoord: 275..422

Blast
[Close]
BLAST of TCONS_00006955-protein vs. Swiss-Prot (Human)
Match: MUTYH (Adenine DNA glycosylase OS=Homo sapiens GN=MUTYH PE=1 SV=1)

HSP 1 Score: 409.068 bits (1050), Expect = 1.077e-138
Identity = 209/470 (44.47%), Postives = 292/470 (62.13%), Query Frame = 0 
Query:    3 HRF-DSKEINFFRKNILKQYDTSQRSLPWRTIAKECQDENKRAYSVWVSEIMLQQTQVATVIDYYNRWIKKWPTVEDLAEATIEEVNTQWSGLGYYSRGKRLHQGAQEVMNKLNGQIPRTSTALQKKLPGVGPYTAGAIASIAYNEPCGVVDGNVIRVLCRLRTIGANSNSNQVQELLWELAKEVVDPDRPGDFNQALMEFGALTCTPKAPKCGDCPLKDICNAYKMTQAKEKKKKTEDKQIYTCPDIED----AGACCYCLPSSVPWEPSLGVMNYPRKEKKKPPASEQFATIILKQNG----KYLLTKRPETGLLAGLWEFPSDQIQPKTTENNSNSETSISEAQLRQKCRDYLKTTFCVEIAAKDLIPCGQVVHVFSHRRHTYHVFKADLKKKDVGINESEKMRWIAKDGFDDIGITTAIRKILALSEG---STQLKGKRPNTGNNDAAKRTLTPNKKQKRMDEFFK 460
            H F D  E+  FR ++L  YD  +R LPWR  A++  D ++RAY+VWVSE+MLQQTQVATVI+YY  W++KWPT++DLA A++EEVN  W+GLGYYSRG+RL +GA++V+ +L G +PRT+  LQ+ LPGVG YTAGAIASIA+ +  GVVDGNV RVLCR+R IGA+ +S  V + LW LA+++VDP RPGDFNQA ME GA  CTP+ P C  CP++ +C A    Q  E+++      +   PD+E+     G C  CLP S PW+ +LGV+N+PRK  +KPP  E  AT +L+Q G    + LL +RP +GLLAGLWEFPS   +P                QL++K        +   + A  L   G+VVH FSH + TY V+   L+ +          RW+ ++ F    ++TA++K+  + +G    T +  KR    +  + K+   P   Q+ +D FF+
Sbjct:   82 HLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRA---RQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSE--------------QLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKK---PRMGQQVLDNFFR 531
The following BLAST results are available for this feature:
BLAST of TCONS_00006955-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MUTYH1.077e-13844.47Adenine DNA glycosylase OS=Homo sapiens GN=MUTYH P... [more]
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