TCONS_00007500-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00007500-protein
Unique NameTCONS_00007500-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length743

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00007500-protein ID=TCONS_00007500-protein|Name=TCONS_00007500-protein|organism=Clytia hemisphaerica|type=polypeptide|length=743bp
SEFHILIDASGNFLRNMYIFLMLMVSISLVDCHYIHDILNHYELLDVDQL
KHHVERRDLSTEGHSRQLHFKFAGTMYNVVLRQRLDILDQGFVAMSVDSE
GGMHPFSVPTLQYYRGTVEGFDDSLVLAHIENDMVTAEIMLGNETIYIEP
SKVHFVNKPNHMLVYKLSDVIWNLTSADSSVNLNQKNCVVPEEVFEKSNN
VDANVNIPFVDVQRSGKKRNRRAVATVKNVCSLTLVADYQFFKNIGGGDK
MSTLNYMIQVVSRVHQIYRSTNFDGIGINIGFKVEKVIIHESFSKDYQHS
YNRAIDGGKVWNVDQLLTVFSRTNFDAKCLSHLFTYQDFDNGIIGLAYVA
SASDYEVGGICTRSYRDHGGPRYLNCGLSSSVNWGRRLLTAEADLVTAHE
IGHNFGSNHDPISCQNSGDAGNYIMYAHSVSGEKENNNKFSKCSRHSMGL
VLKSKRHKCFSEQTEDAFCGNLIVEKGEECDSGLVKPLDDCCDRDCKFKK
DPKTNKPFVCSDSHDPCCDQCRLAPSTKVCRKASQFYCYGETKCSGASKS
CPDAPGLDGREDCGFSMGNCIQGNCTSMCQQKGKISCPCSAGPDSCKICC
KDSADGDCVKLVEDLDEANGIVCELTSEKGKCVDGACIKNVKDVRDEFSG
LFEDFSFSKFVKFMEDNIVGTIITLSLFLWIPASCAVYYIDKKHNDEQTF
MTIWKHPENKELIPKTMPGKLRNLFRSSKRSKQPVRTQYHITS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004230XLOC_004230Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00007500TCONS_00007500Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001762Disintegrin_dom
IPR024079MetalloPept_cat_dom
IPR001590Peptidase_M12B
Vocabulary: Molecular Function
TermDefinition
GO:0008237metallopeptidase activity
GO:0004222metalloendopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001762Disintegrin domainSMARTSM00050DISIN_2coord: 475..557
e-value: 8.0E-7
score: 26.4
IPR001762Disintegrin domainPFAMPF00200Disintegrincoord: 475..553
e-value: 7.0E-11
score: 42.7
IPR001762Disintegrin domainGENE3D4.10.70.10coord: 473..554
e-value: 1.3E-10
score: 41.4
IPR001762Disintegrin domainPROSITEPS50214DISINTEGRIN_2coord: 466..559
score: 11.931
IPR001762Disintegrin domainSUPERFAMILY57552Blood coagulation inhibitor (disintegrin)coord: 475..554
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 224..464
e-value: 4.7E-49
score: 166.5
NoneNo IPR availablePFAMPF13688Reprolysin_5coord: 228..441
e-value: 2.9E-31
score: 109.1
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 227..462
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 229..464
score: 20.914

Blast
[Close]
BLAST of TCONS_00007500-protein vs. Swiss-Prot (Human)
Match: ADA17 (Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1)

HSP 1 Score: 374.785 bits (961), Expect = 2.928e-118
Identity = 254/738 (34.42%), Postives = 381/738 (51.63%), Query Frame = 0 
Query:   35 IHDILNHYELLDVDQLKHH-VERRDLSTEGHSRQL-HFKFAGTMYNVVLRQRLDILDQGFVAMSVDSEGGMHPFSVPTLQYYRGTVEGFDDSLVLAHIENDMVTAEIMLGNETIYIEPSKVHFVN--KPNHMLVYKLSDV--IWNLTSADSSVNLNQKNCVVPEEVFEKSNNVDANVNIPFVDVQRSGKKRNRRAVATVKNVCSLTLVADYQFFKNIGGGDKMSTLNYMIQVVSRVHQIYRSTNFDGIGIN-IGFKVEKVIIHESFS------KDYQHSYNRAIDGGKVWNVDQLLTVFSRTNFDAK------CLSHLFTYQDFDNGIIGLAYVASASDYEVGGICTRSYRDHGGPR--YLNCGLSSSVNWGRRLLTAEADLVTAHEIGHNFGSNHDPIS----CQNSGDAGNYIMYAHSVSGEKENNNKFSKCSRHSMGLVLKSKRHKCFSEQTEDAFCGNLIVEKGEECDSGLVKPLDD-CCDRDCKFKKDPKTNKPFVCSDSHDPCCDQCRLAPSTKVCRKASQFYCYGETKCSGASKSCPDAPGLDGREDCGFSMGNCIQGNCTSMCQQKGKI-SCPCSAGPDSCKICCKDSADGDCVKLVEDLDEANGIVCELTSEKGKC-------VDGACIKNVKDVRDEFSGLFEDFSFSKFVKFMEDNIVGTIITLSLFLWIPASCAVYYIDKKHNDEQTFMTIWKHPENKELIPKTMPGKLRNLFRSSKRSKQPVRTQ 738
            +  +L+ Y++L +  ++ H V +RDL T  H   L  F      + + L    +   Q F  + VD +     ++V    ++ G V G  DS VLAHI +D V   I        IEP    FVN  K   MLVYK  D+  +  L S      L   N    EE+  K      +   P   V R    + R     +KN C L +VAD++F++ +G G++ +T NY+I+++ RV  IYR+T++D  G    G ++E++ I +S        K Y  + +   +    W+V  LL  FS   FD        CL+HLFTYQDFD G +GLAYV S      GG+C ++Y    G +  YLN GL+S+ N+G+ +LT EADLVT HE+GHNFG+ HDP        N    G Y+MY  +VSG+ ENN  FS CS+ S+   ++SK  +CF E++ +  CGN  V++GEECD G++   +D CC+ DC  K+  +      CSD + PCC  C+   + K C++A    C G + C+G S  CP  PG    +     +G C  G C   C+++ ++ SC C+   +SCK+CC+D + G CV  V D ++ N     L   KGK        ++G C K V+DV + F    +  S + F KF+ DNIVG+++  SL  WIP S  V+ +DKK + +   ++++ HP N E++       +R + +     + P R Q
Sbjct:   35 LDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESE-YTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPL-WRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDN----EELLPKGL---VDREPPEELVHRV---KRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFS---FDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERS-NKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQ------CSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP-PPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLS-GRCVPYV-DAEQKN-----LFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLF-HPSNVEMLSSMDSASVR-IIKPFPAPQTPGRLQ 740
The following BLAST results are available for this feature:
BLAST of TCONS_00007500-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ADA172.928e-11834.42Disintegrin and metalloproteinase domain-containin... [more]
back to top