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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00008134-protein ID=TCONS_00008134-protein|Name=TCONS_00008134-protein|organism=Clytia hemisphaerica|type=polypeptide|length=649bp MENKTMLFYIAGLLLFATIGIQAQRSPSKTFLEVVGLSERVVGGKPVSQG MFPWIVFIQANHKYKNNTQTSNLCGGSLIHERWVLTAAHCLPHGERTTRV VVHIGKKSPVSFSQSRTNLPAEKYRVRSIFIHPNYAGSGFSGADLALLHL PRPSKHPTIRLAISPVDDKWYESGSIATVAGWGSTSPHDTQQISQELRSA EVKVVSHKKCNKANSFNGSVLKDMFCASGDGKDACYSDSGGPLMVRDGCR DEWVLIGVVSWGKSCAHKDYPGVYVKLSVYSDWLMDRLYPGRQKSYLSTQ CCCRHQNNEIDENALRTKFKKKRHNEHPANMKLVHLQSRGFSGHYRLLKG PQGPPGEPGRRGSAGLPGRQGPPGDRGKQGPRGRVGAAGKPGLPGNPGKL IGANDKIYSSLEEVNRVLDEVKKLKTELEMTIRETRLGRTIEHAARTCQD IFRSNTGLVNSGKYWLSPQQYDDSAFVGYCNMDDVGGGWTLVYSFKVLRH QNKSLEMVPKPKWRKHEHKEEGASDTAPKYPKDHGAVDYNLWRYIGAEIL IKSVRGDWLKCKSSEASSRYLDIFPPTSSLKKRPIIHKLDCEIVKNEHES VSGCLRLPEAIMWNRSGLVMTESSLLDWAIQKHCSGDQRIDDEVLFYIR Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
Term | Definition |
GO:0004252 | serine-type endopeptidase activity |
GO:0005201 | extracellular matrix structural constituent |
Vocabulary: Biological Process
Term | Definition |
GO:0006508 | proteolysis |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0006508 |
proteolysis |
molecular_function |
GO:0005201 |
extracellular matrix structural constituent |
molecular_function |
GO:0004252 |
serine-type endopeptidase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
None | No IPR available | COILS | Coil | Coil | coord: 411..434 |
None | No IPR available | GENE3D | 2.40.10.10 | | coord: 41..83 e-value: 1.4E-17 score: 63.0 |
None | No IPR available | GENE3D | 2.40.10.10 | | coord: 84..302 e-value: 5.9E-58 score: 195.5 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 344..400 |
IPR001314 | Peptidase S1A, chymotrypsin family | PRINTS | PR00722 | CHYMOTRYPSIN | coord: 75..90 score: 66.22 coord: 232..244 score: 60.6 coord: 140..154 score: 32.16 |
IPR001254 | Serine proteases, trypsin domain | SMART | SM00020 | trypsin_2 | coord: 40..284 e-value: 5.4E-69 score: 245.2 |
IPR001254 | Serine proteases, trypsin domain | PFAM | PF00089 | Trypsin | coord: 41..284 e-value: 2.3E-54 score: 184.4 |
IPR001254 | Serine proteases, trypsin domain | PROSITE | PS50240 | TRYPSIN_DOM | coord: 41..289 score: 32.405 |
IPR001254 | Serine proteases, trypsin domain | CDD | cd00190 | Tryp_SPc | coord: 41..286 e-value: 5.80136E-74 score: 238.33 |
IPR008160 | Collagen triple helix repeat | PFAM | PF01391 | Collagen | coord: 349..399 e-value: 6.0E-10 score: 38.6 |
IPR000885 | Fibrillar collagen, C-terminal | PFAM | PF01410 | COLFI | coord: 417..517 e-value: 5.9E-7 score: 28.9 |
IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | GENE3D | 3.90.215.10 | | coord: 402..545 e-value: 2.0E-8 score: 33.9 |
IPR018114 | Serine proteases, trypsin family, histidine active site | PROSITE | PS00134 | TRYPSIN_HIS | coord: 85..90 |
IPR009003 | Peptidase S1, PA clan | SUPERFAMILY | 50494 | Trypsin-like serine proteases | coord: 7..287 |
IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | SUPERFAMILY | 56496 | Fibrinogen C-terminal domain-like | coord: 441..494 |
Blast
BLAST of TCONS_00008134-protein vs. Swiss-Prot (Human)
Match: TM11D (Transmembrane protease serine 11D OS=Homo sapiens GN=TMPRSS11D PE=1 SV=1) HSP 1 Score: 149.058 bits (375), Expect = 3.593e-39 Identity = 89/256 (34.77%), Postives = 130/256 (50.78%), Query Frame = 0
Query: 33 EVVGLSE-RVVGGKPVSQGMFPWIVFIQANHKYKNNTQTSNLCGGSLIHERWVLTAAHCLPHGERTTRVVVHIGKKSPVSFSQSRTNLPAEKYRVRSIFIHPNYAGSGFSGADLALLHLPRPSKHPT-IRLAISPVDDKWYESGSIATVAGWGSTSPHDTQQISQELRSAEVKVVSHKKCNKANSFNGSVLKDMFCAS--GDGKDACYSDSGGPLMVRDGCRDEWVLIGVVSWGKSCAHKDYPGVYVKLSVYSDWL 284
+++ LSE R++GG +G +PW V ++ N+ + CGGSLI+ W+LTAAHC + ++ S T P + RVR+I IH NY + D+AL+ L I P + GS A V GWG+ ELR +V+++S+ CN +S+NG++L M CA G DAC DSGGPL V++ R W ++G+VSWG C D PGVY +++ Y DW+
Sbjct: 178 DLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHH--------CGGSLINNMWILTAAHCFRSNS---------NPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHEN-DIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQ--EYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPL-VQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
The following BLAST results are available for this feature:
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