TCONS_00014138-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00014138-protein
Unique NameTCONS_00014138-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1431

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00014138-protein ID=TCONS_00014138-protein|Name=TCONS_00014138-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1431bp
MGDVKEKFILDWQTVFPGVAVPDISYFANNETIDKEIILCQERIDDLKFK
LEKEQFVLSKLKSAKKEVKPKNLSKDEDNIVKTDDEDEVISTESVWASVP
KPITPQSSFAEDDLILPPPPSFEELNNDEINKQSVWEFKNKDTTAIVKLE
DNSNKAPETLQPGLSTFQPSARDSRSSSKTSLNEMFDTSSSSLDSTEPFE
KFSNIKTHKKSYSIDENVFDYASPIPVARRLTDPLPTSKTKDNSGVKPKT
APRTLTRSKKDKPLPPLPRKPLRSERNSTKDNVFIPAPPSSPPPALPSPA
PTPERTISQVSSIYDDEHIYTDISELXPAPTPERTISQVSSIYDDEHIYT
DISELNINVKREQVDESCSESEDSYDEVIYENSQMQPKIEPLVDNSSDSL
IEEKSEKPRQLKRSGSHDRQAIALPDDMVIVDVASGPVAGASLEEILNGS
KESLVDDLEESTPKQPVIVVVEENEEDSSDDEEHIYANVEDLILNRISDD
DSDHDPMADSISMGLPSPHYKEMTSDQIQSMLQKIQNNAHSDHSHDESSD
SEESQTPRVKDLKKRITSSSEIKRSPKVKEGSLGRTASTPLPHAIPEKPN
QTPEELEEEHQHLKASRMRKLLVNNLLDSEKAYMDCLEMLTKFMKPLKIS
TESSQPILSTADFKHIFHKAEELLELHSDFYNQLEPRIASWNDAQLIGDL
FTLIMHSFDLYLGYIGNYKVAMETILKCRQANQQFSSIMDQDIKIISLKD
PLKLDGLLYKPVDRMTQYSLILNDLLKYTSPDHPDHVLIVEVSGALFDLF
EQVNVDSSKKKRRQRQLLKELAVVEIDDGERRPRSLILFNDVIICAKLKP
SGDAYVGKWYASLSDINLQPYPNSESTPIVPVSSKTECDKIRANIANMRQ
ELRREHMPLQQVVSSSDASPPFMKRRNGPGVRASSRGLEKIKKKIGEQEK
LLHLISPSIPLNIYHKNGKCYTLLLAVEAERQAWFEALKPRLKRIHARSP
PSIILSSLELQQAFETVLKCQRLGQRFGSQMPSPFLGPTRPMSMDFSMFD
DDKESLTGFLFVSLHYGKGFAKNSDTYVILEMDSYGHFFKKAKTKPCRGS
DPSWEEAFEFEIEACNTLKLTCFNKLRLMGDDISGKCTINLTREKLTDNR
NHTLSVSLDRGQSILNISLCFSTSIDGIKKSPSFSDTGVFGVPIQVVCKR
EKFDIPVIVLSCIKEIEKRGMDEIGIYRLSGVASEIQQLKKLFNEQTQNA
LLVLADTDIHAVAGLLKLYLRELPQSLFTSKLYRKFVQGLSITDSEEKEL
YMVEVLHQLPKPNKITTLYLFDHLRRVTLLEETNKMGTNNLATVFGPTVL
RPPSSNSDKENETSSCNVGTFDIGALDVMSQVGIFRYFLGLKNNERTKLP
ADDLELWRRLDPEKATKMEEDLMITAEEHLI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007911XLOC_007911Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00014138TCONS_00014138Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000008C2_dom
IPR000198RhoGAP_dom
IPR000219DH-domain
IPR011993PH_dom-like
IPR008936Rho_GTPase_activation_prot
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
biological_process GO:0007165 signal transduction
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainSMARTSM00239C2_3ccoord: 1059..1153
e-value: 8.0E-9
score: 45.3
IPR000008C2 domainPFAMPF00168C2coord: 1072..1153
e-value: 6.0E-9
score: 36.0
IPR000008C2 domainGENE3D2.60.40.150coord: 1016..1178
e-value: 1.7E-10
score: 40.6
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 1056..1158
IPR000198Rho GTPase-activating protein domainSMARTSM00324RhoGAP_3coord: 1203..1394
e-value: 3.6E-55
score: 199.3
IPR000198Rho GTPase-activating protein domainPFAMPF00620RhoGAPcoord: 1206..1356
e-value: 2.4E-45
score: 154.0
IPR000198Rho GTPase-activating protein domainPROSITEPS50238RHOGAPcoord: 1192..1380
score: 42.586
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 622..805
e-value: 4.8E-39
score: 145.7
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 623..804
e-value: 1.2E-31
score: 110.2
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 618..806
score: 26.539
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 610..804
IPR011993PH domain-likeGENE3D2.30.29.30coord: 814..998
e-value: 7.0E-12
score: 44.9
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 960..990
coord: 814..879
NoneNo IPR availableGENE3D1.20.900.10coord: 616..813
e-value: 7.1E-43
score: 146.1
NoneNo IPR availableGENE3D4.10.280.30coord: 6..69
e-value: 1.2E-5
score: 24.6
NoneNo IPR availableGENE3D1.10.555.10coord: 1179..1384
e-value: 2.5E-59
score: 199.6
NoneNo IPR availableCDDcd00160RhoGEFcoord: 619..804
e-value: 3.25187E-33
score: 127.414
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 1188..1356

Blast
[Close]
BLAST of TCONS_00014138-protein vs. Swiss-Prot (Human)
Match: ABR (Active breakpoint cluster region-related protein OS=Homo sapiens GN=ABR PE=2 SV=2)

HSP 1 Score: 503.442 bits (1295), Expect = 1.438e-159
Identity = 294/815 (36.07%), Postives = 461/815 (56.56%), Query Frame = 0 
Query:  603 PEELEEEHQHLKASRMRKLLVNNLLDSEKAYMDCLEMLTKFMKPLKISTESSQPILSTADFKHIFHKAEELLELHSDFYNQLEPRIASWNDAQLIGDLFTLIMHSFDLYLGYIGNYKVAMETILKCRQANQQFSSIMDQDIKIISLKDP------LKLDGLLYKPVDRMTQYSLILNDLLKYTSPDHPDHVLIVEVSGALFDLFEQVNVD-------SSKKKRRQRQLLKELAVVEIDDGERRPRSLILFNDVIICAKLKPSGDA----YVGKWYASLSDINLQPYPNSESTPIVPVSSKTECDKIRANIANMRQELRREHMPLQQVVSSSDASPPFMKRRNGPGVRASSRGLEKIKKKIGEQEKLLHLISPSIPLNIYHKNGKCYTLLLAVEAERQAWFEALKPRLKRIHARSPPSIILSSLELQQAFETVLKCQRLGQRFGSQMPSPFLGPTRPMSMDFSMFDDDKESLTGFLFVSLHYGKGFAKNSDTYVILEMDSYGHFFKKAKTKPCR-GSDPSWEEAFEFEIEACNTLKLTCFNKL----------RLMGDDISGKCTINLTREKLTDNRNHTLSVSLDRGQSILNISLCFSTSIDGIKKSPSFSDTGVFGVPIQVVCKREKFDIPVIVLSCIKEIEKRGMDEIGIYRLSGVASEIQQLKKLFNEQTQNALLVLADTDIHAVAGLLKLYLRELPQSLFTSKLYRKFVQGLSITDSEEKELYMVEVLHQLPKPNKITTLYLFDHLRRVTLLEETNKMGTNNLATVFGPTVLRPPSSNSDKENETSSCNVGTFDIGALDVMSQVGIFRYFL 1389
            PE L    +  K   MRKL+++  L SE+ Y++ LE L   MKPLK +  +SQP+L+    + IF+K +++ E+H +FY+ L P++  W+    +G LF  +     +Y  ++ NYKVA+ET  KC Q+N QF  I  +++K+   KD       + ++ LLYKP+DR+T+ +L+L+DLLK+T  DHPD+ L+ +      +    +N D        +  K   RQL+K+  +VE+ +  R+ R + LF DV++CAKLK +       Y  KWY  L+D+       SE++P V      E + ++  I+ ++ E+++E                          +  SR +E++KKK+ E E LL L SP+IP  I+++NGK Y  LL+ + ER  W EA++    ++  +   + +LSS+ELQ    +  K                L     + +  +  DD+   L GFL V +H  KGF ++++ Y  LE+DS+G+F  KAKT+  R  ++P W+E FE E+E   +L++ C+ K             + D I GK  I L  + +     HT  + ++  +  +  S+ F++    +K++PS   TGVFGV I VV KRE+  +P IV  C++E+EKRG++E+GIYR+SGVA++IQ LK +F+   ++ LL+L+D DI+A+AG LKLY RELP+ L T +LY  F++G++++D   KE  M+ +L  LP PN IT L+L +HL+RV   E  NKM  +NLATVFGPT+LRP    S K + TS+      DI + DVM+QV +  Y+L
Sbjct:   76 PEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKI-SEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-----------------------ANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQ----KLQKKDLQAFVLSSVELQVLTGSCFK----------------LRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIK--VEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVES-KAHLTSAA-----DIWSHDVMAQVQVLLYYL 838
The following BLAST results are available for this feature:
BLAST of TCONS_00014138-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ABR1.438e-15936.07Active breakpoint cluster region-related protein O... [more]
back to top