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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00017114-protein ID=TCONS_00017114-protein|Name=TCONS_00017114-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1499bp
MSEKLSVDLFSDDEIPLTPPSKNTNKNFSSSSPRKISVKSCEPPLSDDDD
DDDDIELKSPKPHNVSEKIDREQNQQRPRSVSTSKQKDYSRFVIVSWKIR
QYSTLSKSVKSNTLLHQYRSDATLDSIIVDVRNLLQGNKVLSVAFICHGS
SGAMTLCRDRTVTHENVDSDEMIRKFFFELVDTTMNLDNPNSHLDFLASS
LPTTNVGQQVIKSLQDFLRIPIFASKDILGVELSRQQDSAMGNIGELYFN
ANLLRSWSGSSSQSISNYEKIRTLGRGAYGTAVLYRKKDDDSLVVLKEIT
ILDLSATERQASMNEVRVLGMLSHPNIISYYDSFDEDGTLWIEMEYADGG
TLSDYLAKQDTELEEREILIIFSQMVSAIRYCHDRNILHRDLKTQNIFLT
QDLKVKLGDFGIAKVMNTHNAGNFTVVGTPYYISPEMCEGKPYDSKSDIW
ALGCILYEMAQLTKTFDGTNLPALITKIVKGTFAPVKETYSPDFRALVRD
LLQKDPIARPTAEEILFQRLPELLQQYNELDDTIESQQNFVVTGRTRSLL
YYCDVTTMNLYPILELPQKIQVAEVSVGLAHIVIVSVERGVFSWGDNSYG
QLGHGDFEAREHPTEIVLLRGKSIVKACCGDYFTTFLSDNGLVLTCGQGE
YGSLGHGDWNSIARPKLLDALLTLDIASLETGAYHIAITTAEGHAFTWGR
GDDGRLGHGNESHLCVPTRVKFDSDHVFIRGVQCSMDGTMFIADTGTTFA
CGKNDGNKLGINPRQGFLLQFRSRSNKVITSTSIPTLNKDMCKYQVSAIK
FGGQHCCLINENGQAFSSGNNTEAQLGCGNTKTRDVLTPTKLFEGARISL
IACGSTFTFAGVQESSRDGKSNINSVYFWGTKPRSRRSRTISSSDSSAYS
AARSARGRRISTVDEDGFLQQDELYNSINSDSRASSSGGFESSRKSSRLD
SGRLSTESYGESEVDDSRRTFLRNILKGSNTQTLNMVPKESTPVTVPQIV
FKFQSIGGIEGWDEEEEFPVDLHDIKCFQDHVIIHLETTAPPPKCKKLEA
QKSLDSSLSLSGSRSVVTNRGESSGTNSEMDMSGEVPTWIRNELEDGIPV
FEEEISPAPPPEAPLYIDSGNASDDEENPASPAGSPAKRPFPFNRTKSYD
TLSRRGSMTLLGRDPNFNIIPKLKKQNPMLKRVEETDDLGKTETRIIDGV
AVTVSTTEISEDISTSPNLNAKRVGSAKKASPKPVIGNVSPEVKRKMKSM
SADAKKREKQKKPADGDITARSSSAVEYTPVEDIYSEELAAKLHQEKKSE
QPQRSKSSKLPLSKARAKRVSKQKEQKSDFPQPRPSKNVPKHRKAKQMTS
PDANNNNEIDQNLFDEFQRQAKISEEKLRKEIEKIQEDKEKREELLREAY
EKELKAKEEWTLKKDEEAKQREEALKDEIKDLKTDLSSQNNKLQDNHNIL
LSVQEQLMLLQKGQLRQSTTETPHQASTQSSSNDSLKDKQMKSSICSVM Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0005524 | ATP binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 1407..1446 |
| None | No IPR available | COILS | Coil | Coil | coord: 1364..1405 |
| None | No IPR available | GENE3D | 2.130.10.30 | | coord: 730..886
e-value: 1.5E-23
score: 82.6
coord: 546..729
e-value: 1.4E-47
score: 161.7 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 235..363
e-value: 6.9E-27
score: 93.3 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 364..545
e-value: 2.6E-57
score: 193.2 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1..84 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1216..1366 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 929..965 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1462..1499 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1103..1149 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 886..906 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1051..1083 |
| None | No IPR available | CDD | cd08215 | STKc_Nek | coord: 267..516
e-value: 2.60402E-138
score: 426.879 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PRINTS | PR00633 | RCCNDNSATION | coord: 591..607
score: 38.24
coord: 679..695
score: 31.37
coord: 802..820
score: 27.19
coord: 572..585
score: 25.0
coord: 695..709
score: 40.0 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PFAM | PF00415 | RCC1 | coord: 812..860
e-value: 6.4E-8
score: 33.0
coord: 591..637
e-value: 2.5E-13
score: 50.3
coord: 692..742
e-value: 3.0E-8
score: 34.1 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PROSITE | PS50012 | RCC1_3 | coord: 693..745
score: 10.966 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PROSITE | PS50012 | RCC1_3 | coord: 641..692
score: 10.625 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PROSITE | PS50012 | RCC1_3 | coord: 589..640
score: 13.559 |
| IPR000408 | Regulator of chromosome condensation, RCC1 | PROSITE | PS50012 | RCC1_3 | coord: 813..864
score: 10.424 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 268..520
e-value: 4.3E-82
score: 288.7 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 268..516
e-value: 1.8E-63
score: 214.2 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 268..523
score: 48.188 |
| IPR025592 | Domain of unknown function DUF4347 | PFAM | PF14252 | DUF4347 | coord: 93..258
e-value: 6.9E-9
score: 35.7 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 274..297 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 387..399 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 265..518 |
| IPR009091 | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | SUPERFAMILY | 50985 | RCC1/BLIP-II | coord: 558..882 |
Blast
BLAST of TCONS_00017114-protein vs. Swiss-Prot (Human)
Match: NEK8 (Serine/threonine-protein kinase Nek8 OS=Homo sapiens GN=NEK8 PE=1 SV=1) HSP 1 Score: 398.282 bits (1022), Expect = 3.323e-122 Identity = 246/672 (36.61%), Postives = 354/672 (52.68%), Query Frame = 0
Query: 265 ISNYEKIRTLGRGAYGTAVLYRKKDDDSLVVLKEITILDLSATERQASMNEVRVLGMLSHPNIISYYDSFDEDGTLWIEMEYADGGTLSDYLAKQ-DTELEEREILIIFSQMVSAIRYCHDRNILHRDLKTQNIFLTQD-LKVKLGDFGIAKVMNTHNAGNFTVVGTPYYISPEMCEGKPYDSKSDIWALGCILYEMAQLTKTFDGTNLPALITKIVKGTFAPVKETYSPDFRALVRDLLQKDPIARPTAEEILFQRLP--ELLQQYNELDDT-IESQQNFVVTGRTRSLLYYCDVTTMNLYPI---------------------LELPQ-KIQVAEVSVGLAHIVIVSVERGVFSWGDNSYGQLGHGDF--EAREHPTEIVLLR------GKSIVKACCGDYFTTFLSDNGLVLTCGQGEYGSLGHGDWNSIARPKLLDALLTLDIASLETGAYHIAITTAEGHAFTWGRGDDGRLGHGN-ESHLCVPTRVKFDSDHVFIRGVQCSMDGTMFIADTGTTFACGKNDGNKLGIN---------PRQGFLLQFRSRSNKVITSTSIPTLNKDMCKYQVSAIKFGGQHCCLINENGQAFSSGNNTEAQLGCGNTKTRDVLTPTKL--FEGARISLIACGSTFTFAGVQESSRDGKSNINSVYFWGTKPRSRRSR 889
+ YE+IR +GRGA+G L +K D LV++K+I + ++ ERQA+ NE +VL +L+HPN+I YY++F ED L I MEYA GGTL++++ K+ ++ LEE IL F Q++ A+ + H ILHRDLKTQNI L + + VK+GDFGI+K++++ + +TVVGTP YISPE+CEGKPY+ KSDIWALGC+LYE+A L + F+ NLPAL+ KI+ GTFAP+ + YSP+ R LV LL +P RP I+ Q L LL + ++ + + V T S + P+ L LP +V +V+ G V+ + W G G G A E P + R G +I CGD+FT L+D G+++T G G G LGHG I++P +++ALL ++ + GA H+ + E F WGRGD GRLG G ESH C P +V R V C +D +M + G ACG N NKLG++ P Q + + ++ T + + D + + +I G H + +G ++ G+N QLG NT+ R P K+ EG +++++ACG FT A ES VY WG R R R
Sbjct: 1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKA-YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGA-GGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSC-PQQVPMPPGQEAQR-VVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQ--------QVEEALSFTLLGSAPLD--QEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGT-NTR-RGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAES---------EVYSWGKGARGRLGR 647
The following BLAST results are available for this feature:
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