TCONS_00017900-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00017900-protein
Unique Name	TCONS_00017900-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	681

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00017900-protein ID=TCONS_00017900-protein|Name=TCONS_00017900-protein|organism=Clytia hemisphaerica|type=polypeptide|length=681bp
MATEVDGESVDESNVLKILLATDCHIGYAEKDPIRQNDSFVSFEEILQLA
QKEKVDMILLGGDLFHENKPSRHTIHRTLSLLRKYCLGDKDCLLEFMSDA
EVNFAHCDFKHANYLDPNLNVAYPLFSVHGNHDDPTGEGSLSAIDILSAA
GVLNHFGKAENCDKIDMTPVLLKKGDTKLALYGLGSMRDERLYKTFCLKN
VHMLRPREEPDSWFNIFVIHQNRAKHGPKNHIPESFLDEFLDLVVWGHEH
ECLITPVASESGKNFFVTQPGSSIATSLSEGESEQKKVGLLEISGKQFRI
KEIELKTVRQFYIEHVVLSDTSLNSHEDEKVYNYLTEKIEQLITRAGNNR
SGHEKQPELPLIRIKVEYSGGYEIINPHRFGQQFVGRVANSKDLLLFYKK
KTYSATSRTKDETDGVGRGQEMTYSQASGIKMEDLINEYLTSDSNIGNLS
ILSERKLSKALNEFVLKDEKDAIPELVKYQLRKTQTELKRRNLVEEEKID
AEISVIKENEENMDEEQENEEIEKVLRESSMNKTNRVSNKDAFDEFDLDE
EDDDIPSTKTTRGRGRGRGRGKTTSTRGTRGGRGRGSRGGRGGAKGSRKA
DKEELDITQKTIQSSFMSTATGRSKKNVVDLSMYDDDDIPSTKSFRSQRS
KKVDYTYLDDDEDDQENPFDQINQPSKRARR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010036	XLOC_010036	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00017900	TCONS_00017900	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR007281	Mre11_DNA-bd
IPR029052	Metallo-depent_PP-like
IPR003701	Mre11
IPR004843	Calcineurin-like_PHP_ApaH

Vocabulary: **Molecular Function**
Term	Definition
GO:0030145	manganese ion binding
GO:0004519	endonuclease activity
GO:0008408	3'-5' exonuclease activity
GO:0016787	hydrolase activity

Vocabulary: **Cellular Component**
Term	Definition
GO:0005634	nucleus
GO:0030870	Mre11 complex

Vocabulary: **Biological Process**
Term	Definition
GO:0006302	double-strand break repair

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006302	double-strand break repair
cellular_component	GO:0030870	Mre11 complex
cellular_component	GO:0005634	nucleus
molecular_function	GO:0008408	3'-5' exonuclease activity
molecular_function	GO:0004519	endonuclease activity
molecular_function	GO:0016787	hydrolase activity
molecular_function	GO:0030145	manganese ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 499..532
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 547..607
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 632..681
None	No IPR available	CDD	cd00840	MPP_Mre11_N	coord: 17..279 e-value: 8.1135E-58 score: 193.639
IPR007281	Mre11, DNA-binding	SMART	SM01347	Mre11_DNA_bind_2	coord: 298..464 e-value: 1.8E-67 score: 240.1
IPR007281	Mre11, DNA-binding	PFAM	PF04152	Mre11_DNA_bind	coord: 298..464 e-value: 2.3E-47 score: 161.3
IPR029052	Metallo-dependent phosphatase-like	GENE3D	3.60.21.10		coord: 4..309 e-value: 4.6E-76 score: 255.4
IPR029052	Metallo-dependent phosphatase-like	SUPERFAMILY	56300	Metallo-dependent phosphatases	coord: 120..345 coord: 16..86
IPR003701	DNA double-strand break repair protein Mre11	PIRSF	PIRSF000882	DSB_repair_MRE11	coord: 2..675 e-value: 9.2E-221 score: 732.7
IPR003701	DNA double-strand break repair protein Mre11	TIGRFAM	TIGR00583	TIGR00583	coord: 14..401 e-value: 5.9E-155 score: 514.1
IPR004843	Calcineurin-like phosphoesterase domain, ApaH type	PFAM	PF00149	Metallophos	coord: 16..252 e-value: 1.6E-13 score: 51.5

Blast

[Close]

BLAST of TCONS_00017900-protein vs. Swiss-Prot (Human)
Match: MRE11 (Double-strand break repair protein MRE11 OS=Homo sapiens GN=MRE11 PE=1 SV=3)

HSP 1 Score: 543.888 bits (1400), Expect = 0.000e+0
Identity = 294/665 (44.21%), Postives = 421/665 (63.31%), Query Frame = 0

Query:    7 GESVDESNVLKILLATDCHIGYAEKDPIRQNDSFVSFEEILQLAQKEKVDMILLGGDLFHENKPSRHTIHRTLSLLRKYCLGDKDCLLEFMSDAEVNFAHCDFKHANYLDPNLNVAYPLFSVHGNHDDPTGEGSLSAIDILSAAGVLNHFGKAENCDKIDMTPVLLKKGDTKLALYGLGSMRDERLYKTFCLKNVHMLRPREEPDSWFNIFVIHQNRAKHGPKNHIPESFLDEFLDLVVWGHEHECLITPVASESGKNFFVTQPGSSIATSLSEGESEQKKVGLLEISGKQFRIKEIELKTVRQFYIEHVVLSD-----TSLNSHEDEKVYNYLTEKIEQLITRAGNNRSGHEKQPELPLIRIKVEYSGGYEIINPHRFGQQFVGRVANSKDLLLFYKKKTYSATSRTKDETDGVGRGQEMTY-SQASGIKMEDLINEYL-TSDSNIGNLSILSERKLSKALNEFVLKDEKDAIPELVKYQLRKTQTELKRRNL-VEEEKIDAEISVIKENEENMDEEQENEEIEKVLRESSMNKTNRVS----NKDAFDEFDLDEE-----DDDIPSTKTTRGRGRGRGRGKTTSTRGTRGGRGRG-----------SRGGRGGAKGSRKADKEELDITQKTIQSSFMSTATGRSKKNV-VDLSMYDDDDIPST 642
             +++D+ N  KIL+ATD H+G+ EKD +R ND+FV+ +EIL+LAQ+ +VD ILLGGDLFHENKPSR T+H  L LLRKYC+GD+    E +SD  VNF    F   NY D NLN++ P+FS+HGNHDDPTG  +L A+DILS AG +NHFG++ + +KID++PVLL+KG TK+ALYGLGS+ DERLY+ F  K V MLRP+E+ +SWFN+FVIHQNR+KHG  N IPE FLD+F+DLV+WGHEHEC I P  +E  + F+++QPGSS+ TSLS GE+ +K VGLL I G++  + +I L TVRQF++E +VL++        N    + + ++  EKIE+++  A   R G+  QPE PL+R++V+YSGG+E  +  RF Q+FV RVAN KD++ F++ +      +T +E   +  G+ +T  S+ + +++EDL+ +Y  T++ N+  LS+L+ER + +A+ EFV K+EKDAI ELVKYQL KTQ  LK R++   E+KID E+   +E  +    E+++E  E + R  ++   +  S    + D     DL E+     DD I +            RG       +RGG  RG           SR  +     SR      +D  + T Q    +  T    + + VD S  ++D  P+T
Sbjct:    4 ADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQ-QLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFRHR--EQKEKTGEE---INFGKLITKPSEGTTLRVEDLVKQYFQTAEKNV-QLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAEQMANDSDDSISAATNKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLETSTRSRNSKTAVSASRNMSI--IDAFKSTRQQPSRNVTTKNYSEVIEVDESDVEEDIFPTT 659

The following BLAST results are available for this feature:

BLAST of TCONS_00017900-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00017900-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
MRE11	0.000e+0	44.21	Double-strand break repair protein MRE11 OS=Homo s...	[more]

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TCONS_00017900-protein (polypeptide) - C. hemisphaerica