TCONS_00018776-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00018776-protein
Unique NameTCONS_00018776-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length402

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00018776-protein ID=TCONS_00018776-protein|Name=TCONS_00018776-protein|organism=Clytia hemisphaerica|type=polypeptide|length=402bp
MGMEKYDRETKKLVGRGAFGHVYLYQSLSDRKEIIIKQITIDDLTTDQRK
GVMNEINLSSMFDHPNIIKYMEYFLEDNVFNIVMEYAAGGNLYDYLHQRQ
KEDRFLEEEEVTKFFVQIVRALHHIHRYYILHRDMKTHNILLDRRKKVIK
ICDFGISKFLTQTSAETTVGTAHYMSPEVVEGKSYNYKSDIWSLGCILHE
LITLKRTFDAEFLSAIISKILRCDYSPMPMNYSDELRQLVKDILQIDPAK
RPDVNAILAAPVLINAYFDLETDVGRIPCYHWNSGNNAQRRKPKKGDKSD
RSGTNQSAGSDSGGSGNTPTSGGRTIGAVDDSVYRTQSFTSWGDEATRAN
HEQTSIVYMWGSVSDTPTLLTLPFHDQLVTSVYTGKTKKLGLTSYGRVVS
WE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010514XLOC_010514Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00018776TCONS_00018776Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 124..142
score: 30.39
coord: 84..97
score: 41.41
coord: 232..254
score: 24.62
coord: 189..211
score: 35.54
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 8..263
e-value: 1.2E-81
score: 287.2
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 9..262
e-value: 2.2E-66
score: 223.8
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 8..263
score: 48.499
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 3..269
e-value: 9.6E-34
score: 114.7
NoneNo IPR availableGENE3D1.10.510.10coord: 241..271
e-value: 0.074
score: 11.9
NoneNo IPR availableGENE3D1.10.510.10coord: 76..240
e-value: 5.9E-59
score: 199.1
NoneNo IPR availableGENE3D3.30.200.20coord: 2..75
e-value: 1.2E-18
score: 66.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 285..327
NoneNo IPR availableCDDcd08215STKc_Nekcoord: 5..263
e-value: 4.26617E-124
score: 361.395
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 14..37
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 130..142
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 10..273

Blast
[Close]
BLAST of TCONS_00018776-protein vs. Swiss-Prot (Human)
Match: NEK8 (Serine/threonine-protein kinase Nek8 OS=Homo sapiens GN=NEK8 PE=1 SV=1)

HSP 1 Score: 311.612 bits (797), Expect = 7.126e-100
Identity = 168/401 (41.90%), Postives = 238/401 (59.35%), Query Frame = 0 
Query:    3 MEKYDRETKKLVGRGAFGHVYLYQSLSDRKEIIIKQITIDDLTTDQRKGVMNEINLSSMFDHPNIIKYMEYFLEDNVFNIVMEYAAGGNLYDYLHQRQKEDRFLEEEEVTKFFVQIVRALHHIHRYYILHRDMKTHNILLDRRKKVIKICDFGISKFLTQTS-AETTVGTAHYMSPEVVEGKSYNYKSDIWSLGCILHELITLKRTFDAEFLSAIISKILRCDYSPMPMNYSDELRQLVKDILQIDPAKRPDVNAILAAPVLINAYFDLETDVGRIPCYHWNSGNNAQRRKPKKGDKSDRSGTNQSAGSDSGGSGNTPTSGGRTIGAVDDSVYRTQSFTSWGDEATRANHEQTSIVYMWGSVSDTPTLLTLPFHDQLVTSVYTGKTKKLGLTSYGRVVSWE 402
            MEKY+R   ++VGRGAFG V+L    +D+K +IIKQI ++ +T ++R+   NE  +  + +HPN+I+Y E FLED    I MEYA GG L +++ +R   +  LEEE +  FFVQI+ ALHH+H + ILHRD+KT NILLD+ + V+KI DFGISK L+  S A T VGT  Y+SPE+ EGK YN KSDIW+LGC+L+EL +LKR F+A  L A++ KI+   ++P+   YS ELRQLV  +L ++PA+RP ++ I+A P+ I A  +L TDVG +              + ++ +KS        A S++G    +    G   G V  ++                     S VY WG    TP  L LP  +  V  V  G+T+K G+T  GR++ WE
Sbjct:    1 MEKYER--IRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC--NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSV--------------RMRRAEKS-------VAPSNTGSRTTSVRCRGIPRGPVRPAI-----------------PPPLSSVYAWGGGLGTP--LRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWE 357
The following BLAST results are available for this feature:
BLAST of TCONS_00018776-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NEK87.126e-10041.90Serine/threonine-protein kinase Nek8 OS=Homo sapie... [more]
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