TCONS_00021482-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00021482-protein
Unique NameTCONS_00021482-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length756

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00021482-protein ID=TCONS_00021482-protein|Name=TCONS_00021482-protein|organism=Clytia hemisphaerica|type=polypeptide|length=756bp
MGNGASASGVESSQTTISLDGGEKIETARLKLLYPEIRAELKQKDELVQK
QNKQIKTYEDEIKNLKREINQLKSVLEATTTKSIQEETILEESDSADQGK
SKNRFLDVVNNVRNKRIAISAETSDKKTDVDLANVTKTPKSAEARKLIMK
AFQGNQFLKHLEDGQVKEIVMYMHLINYKEGDYLIKEGDSGNALFVINKG
KLQVHQGDKVLGSPMQPGILFGELAILYDCTRTASVKALEDVEVWSIERQ
VFQSVMKRTGNLRRDEHYQFLKSAPIFSGLDTEKLYKITEVCEEESFQEG
EYIIREGERGDSFFILKEGMVKVLKLLEGHTEPQEIRTLNKGDYFGEKAL
LSEDLRTASIIALAGGVNCLVIERENFLSFIGDLDSIKEKDYGDLERKAA
AQLSKKTSSESTVSQKSTSSQPPKEKHRTSTEIIRAEFETKRLSAFKLLS
TLGMGGFGRVELIQDKENKSKTYALKCLIKQHVVETKQQEHVFNEKKILM
SLDSPFIINLYKTFKDKRFVYFLMEVCLGGELWTILRDKDYFDEPTSRFY
TACVVEAFEYLHARGIVFRDLKPENLLLDNRGYVKLVDFGFAKKIKSGTK
TWTFCGTPEYVAPEIILNKGHDCSADYWSLGVLIYELMTGNPPFTSSDPM
NTYNIILRGIDALEFSSLISRNAQLLIKRLCKENPMERLGNQKDGVMDIR
KHKWFTGFHWSGLQARTLQAPIMPKIKDASDHSNFDYFSPNKDIPPEENS
GWDSEF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012048XLOC_012048Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00021482TCONS_00021482Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002374cGMP_dep_kinase
IPR000595cNMP-bd_dom
IPR000719Prot_kinase_dom
IPR000961AGC-kinase_C
IPR014710RmlC-like_jellyroll
IPR017441Protein_kinase_ATP_BS
IPR018488cNMP-bd_CS
IPR035014STKc_cGK
IPR018490cNMP-bd-like
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005524ATP binding
GO:0004692cGMP-dependent protein kinase activity
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004692 cGMP-dependent protein kinase activity
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 41..82
NoneNo IPR availableGENE3D1.10.510.10coord: 544..751
e-value: 1.7E-55
score: 187.3
NoneNo IPR availableGENE3D3.30.200.20coord: 396..543
e-value: 6.5E-24
score: 83.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 737..756
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 406..430
NoneNo IPR availableCDDcd00038CAP_EDcoord: 157..264
e-value: 1.0299E-25
score: 102.019
NoneNo IPR availableCDDcd00038CAP_EDcoord: 276..390
e-value: 4.85075E-28
score: 108.953
IPR002374cGMP-dependent kinasePRINTSPR00104CGMPKINASEcoord: 335..342
score: 62.5
coord: 282..296
score: 41.21
coord: 353..362
score: 71.82
coord: 367..376
score: 60.91
coord: 377..391
score: 43.64
IPR002374cGMP-dependent kinasePIRSFPIRSF000559cGMP-dep_kinasecoord: 10..756
e-value: 0.0
score: 1029.2
IPR000595Cyclic nucleotide-binding domainSMARTSM00100cnmp_10coord: 157..271
e-value: 1.5E-20
score: 84.3
coord: 276..399
e-value: 5.3E-26
score: 102.4
IPR000595Cyclic nucleotide-binding domainPFAMPF00027cNMP_bindingcoord: 177..258
e-value: 1.9E-19
score: 69.4
coord: 295..381
e-value: 2.4E-19
score: 69.1
IPR000595Cyclic nucleotide-binding domainPROSITEPS50042CNMP_BINDING_3coord: 157..273
score: 32.369
IPR000595Cyclic nucleotide-binding domainPROSITEPS50042CNMP_BINDING_3coord: 276..398
score: 33.553
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 446..705
e-value: 1.5E-89
score: 313.5
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 447..705
e-value: 5.5E-70
score: 235.6
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 446..705
score: 47.368
IPR000961AGC-kinase, C-terminalSMARTSM00133pkinase_C_6coord: 706..756
e-value: 9.3E-5
score: 31.8
IPR000961AGC-kinase, C-terminalPROSITEPS51285AGC_KINASE_CTERcoord: 706..756
score: 10.835
IPR014710RmlC-like jelly roll foldGENE3D2.60.120.10coord: 37..261
e-value: 1.0E-32
score: 112.4
IPR014710RmlC-like jelly roll foldGENE3D2.60.120.10coord: 262..392
e-value: 9.5E-31
score: 105.6
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 452..476
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00888CNMP_BINDING_1coord: 184..200
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00889CNMP_BINDING_2coord: 345..362
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00888CNMP_BINDING_1coord: 303..319
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00889CNMP_BINDING_2coord: 221..238
IPR035014cGMP-dependent protein kinase, catalytic domainCDDcd05572STKc_cGKcoord: 452..712
e-value: 1.10169E-172
score: 498.289
IPR018490Cyclic nucleotide-binding-likeSUPERFAMILY51206cAMP-binding domain-likecoord: 122..258
IPR018490Cyclic nucleotide-binding-likeSUPERFAMILY51206cAMP-binding domain-likecoord: 262..389
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 424..746

Blast
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BLAST of TCONS_00021482-protein vs. Swiss-Prot (Human)
Match: KGP2 (cGMP-dependent protein kinase 2 OS=Homo sapiens GN=PRKG2 PE=1 SV=1)

HSP 1 Score: 695.271 bits (1793), Expect = 0.000e+0
Identity = 346/731 (47.33%), Postives = 498/731 (68.13%), Query Frame = 0 
Query:   41 LKQKDELVQKQNKQIKTYEDEIKNLKREINQLKSVLEATTTKSIQEETILEESDSADQGKSKNRFLDVVNNVRNKRIAISAETSDKKTDVDLA-----NVTKTPKSAEARKLIMKAFQGNQFLKHLEDGQVKEIVMYMHLINYKEGDYLIKEGDSGNALFVINKGKLQVHQGDKVLGS-PMQPGILFGELAILYDCTRTASVKALEDVEVWSIERQVFQSVMKRTGNLRRDEHYQFLKSAPIFSGLDTEKLYKITEVCEEESFQEGEYIIREGERGDSFFILKEGMVKVLKLLEGHTEPQEIRTLNKGDYFGEKALLSEDLRTASIIALAGGVNCLVIERENFLSFIGDLDSIK---EKDYGDLERKAAAQLSKKTSSESTVSQKSTSSQPPKEKHRTSTEIIRAEFETKRLSA------FKLLSTLGMGGFGRVELIQDKENKSKTYALKCLIKQHVVETKQQEHVFNEKKILMSLDSPFIINLYKTFKDKRFVYFLMEVCLGGELWTILRDKDYFDEPTSRFYTACVVEAFEYLHARGIVFRDLKPENLLLDNRGYVKLVDFGFAKKIKSGTKTWTFCGTPEYVAPEIILNKGHDCSADYWSLGVLIYELMTGNPPFTSSDPMNTYNIILRGIDALEFSSLISRNAQLLIKRLCKENPMERLGNQKDGVMDIRKHKWFTGFHWSGLQARTLQAPIMPKIKDASDHSNFDYFSPNKDIPPEENSGWDSEF 756
            LK+  E + KQ   I    +E++N   ++N+L+ V+       +Q            +   K   L  +++ R  +  +SAE + +  D++          +  K +  +KLI  A   NQFLK L+  Q+K++V  M+  NY++G Y+IK+G+ GN +FV+ +G+L+V QG+K+L S PM     FGELAILY+CTRTASVKA+ +V+ W+++R+VFQ++M+RT   R +++  FL+S  +   L  +KL KI +  E E + +G+YIIREGE G +FFIL +G VKV +  EGH +PQ I+TL KG+YFGEKAL+S+D+R+A+IIA    V CLVI+RE F   +G  + ++   E    +L R    + +K++ S   +S+              S E+I+ + +  R S+       ++++TLG+GGFGRVEL++ K N++  +A+KC+ K+H+V+TKQQEHV++EK+IL  L SPFI+ LY+TFKD ++VY L+E CLGGELW+ILRD+  FDEPTS+F  ACV EAF+YLH  GI++RDLKPENL+LD  GY+KLVDFGFAKKI SG KTWTFCGTPEYVAPE+ILNKGHD S D+WSLG+L+YEL+TGNPPF+  D M TYN+IL+GI+ ++F   I+R  + LI+RLC++NP ERLGN K+G+ DI+KH+W  GF+W GL+AR+L +P+  ++K   DHS FD + P K +PP+E SGWD +F
Sbjct:   51 LKELREQLSKQTVAIAELTEELQNKCIQLNKLQDVVHMQGGSPLQASP----DKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMW--TTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKA------------LSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVK-NENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF 762
The following BLAST results are available for this feature:
BLAST of TCONS_00021482-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
KGP20.000e+047.33cGMP-dependent protein kinase 2 OS=Homo sapiens GN... [more]
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