TCONS_00021757-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00021757-protein
Unique Name	TCONS_00021757-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1349

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00021757-protein ID=TCONS_00021757-protein|Name=TCONS_00021757-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1349bp
MESVEVFLTRLKLEQYIENLHVNGIFHVNEITEQVLSKCGIEKIGHQKRI
LTELAKLNFSDSPEMNHSTIAETNDAPALPPKRSATATSRTIHKTPPTPP
RRSVSTRPVRPPPRTSASVARGGSLPKGAKLNNENYFVINAAPAPPINTN
INNTEVTNPTLPPQIPPRIDIGEAQQIENNNNGLSPKRRAPPPPTPNHRN
EKGEPTTGILIEVDPPESPIASPPLSPPVPAPRTRAKVLPTVQFEEVVAK
TEPDTTHSEDEASDDDIFPPEDDDDSPSESESKVLTISMRENTKTFERLL
SENTIPRTESEKRDNRKSRFLTSGKKGYLHKKGGQDGKKPPQKRWVEFDG
IELKYFKEKGDDPRQIIPVSRMMDVQAQPDAKKPTFHLLTPNRKFTFFDN
NGDLNETSVWMQCLMEAILNKPDVPCLVGGQMSDPDMEGWLLKQGHGVLV
QDFKRRYVAIKDDKLCYYNSFSHFEEDLPIFKLQMSLASLKEDVSRRRLL
LSYHTQRTYVFEVPPKDSYEQWKDAIEGSIEKALGDDSVLQILMKDESNL
RCADCGTTKNVNWASIKCLVIICKRCCGRHRGYSQKFFLPRSILMDVKIW
TNELIEIFKLMGNKNANMLWAAKLPPDEQISPDCSTEERITFLKDKYIHK
KYFKLSEHFGLEHELGEALRKAVVTEDLIQTFRLIQSGASVMYIPEESED
KRTPYQLAEDAGQSLQVALLEIYKGNLSIEEWEKEQQEEAARIEEQLRRL
PQIQDDNTVYYEKAGELMMKMHEKENWRDARMFQLKEKIIHRSIRTEEGK
PRTEEVIDLRQMEEIKALDDQVTFFLQTSSNHSARTYYFKAFTPEDCRSW
FTAIKNKQVFEVALDKQEVSADKIPYLVDKCIKYMETNALTDMKTLTQEG
IYRKNGSQAQIRDLTKLFNQDAANVRLDISEYYDVHVICGLLKKYLRDLP
EPLVTNILYESFLQNTYEGEIEHNERLYRYRDLIKGLPAINLLCLRALIL
HLHLVVELSSFNLMTMENVSLLFGPIICSCGRTLNQDKLRLEYKVLQDLL
TYYKWLFDVDENETKSQEAILKFTKSAAESTVTPTINEGGMQITIYLKNI
EDRMLVDSSTRPSDVCAFFIKTHDLDRATNWALFESINDGTFERPLSSKE
SVYDLALSLSDNGKLIVKENYLLEKLAPHQSASFNSGGVIHFLRDKSSWK
KVYLEIKQGMLRVASSKDSSKDIDKFGIVDAQVLLYSGIDPKKKGPANNK
FGFMIKVNGSISNTQPRYFCSDQEEIINMFMAVILNLRYPVGIWTDRCSK
DFRETEAESNRNSQFWGRQSMVIQQEGAAHRFTEQLQSKRSTLRRLFRT

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_012211	XLOC_012211	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00021757	TCONS_00021757	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001849	PH_domain
IPR000198	RhoGAP_dom
IPR001660	SAM
IPR001164	ArfGAP
IPR011993	PH_dom-like
IPR008936	Rho_GTPase_activation_prot
IPR029071	Ubiquitin-rel_dom
IPR013761	SAM/pointed

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding
GO:0005096	GTPase activator activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0005096	GTPase activator activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 729..749
None	No IPR available	GENE3D	1.10.555.10		coord: 872..1071 e-value: 1.2E-46 score: 158.0
None	No IPR available	GENE3D	3.10.20.90		coord: 1090..1172 e-value: 4.4E-8 score: 33.1
None	No IPR available	GENE3D	1.10.150.50		coord: 1..57 e-value: 2.0E-10 score: 40.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 178..342
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 65..129
None	No IPR available	CDD	cd00821	PH	coord: 763..854 e-value: 2.22669E-5 score: 43.3002
None	No IPR available	SUPERFAMILY	57863	ArfGap/RecO-like zinc finger	coord: 538..653
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 435..533 e-value: 1.8E-10 score: 50.8 coord: 1166..1291 e-value: 6.9 score: 14.3 coord: 761..861 e-value: 0.0098 score: 25.1 coord: 323..421 e-value: 1.6E-8 score: 44.3
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 434..531 score: 10.759
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 322..419 score: 9.897
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 760..859 score: 9.125
IPR000198	Rho GTPase-activating protein domain	SMART	SM00324	RhoGAP_3	coord: 872..1079 e-value: 3.4E-42 score: 156.2
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 875..1030 e-value: 6.4E-37 score: 126.6
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 862..1057 score: 39.69
IPR001660	Sterile alpha motif domain	SMART	SM00454	SAM_4	coord: 1..60 e-value: 3.8E-4 score: 29.8
IPR001660	Sterile alpha motif domain	PFAM	PF00536	SAM_1	coord: 2..57 e-value: 2.0E-7 score: 31.3
IPR001164	Arf GTPase activating protein	SMART	SM00105	arf_gap_3	coord: 537..659 e-value: 7.1E-20 score: 82.0
IPR001164	Arf GTPase activating protein	PFAM	PF01412	ArfGap	coord: 539..653 e-value: 7.4E-26 score: 90.4
IPR001164	Arf GTPase activating protein	PROSITE	PS50115	ARFGAP	coord: 537..652 score: 18.524
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 247..423 e-value: 5.6E-12 score: 45.1
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 1185..1287 e-value: 0.0084 score: 15.7
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 752..871 e-value: 4.7E-8 score: 32.0
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 430..751 e-value: 1.8E-13 score: 49.6
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 1188..1288
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 431..535
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 760..856
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 325..424
IPR008936	Rho GTPase activation protein	SUPERFAMILY	48350	GTPase activation domain, GAP	coord: 872..1061
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 1104..1171
IPR013761	Sterile alpha motif/pointed domain	SUPERFAMILY	47769	SAM/Pointed domain	coord: 2..58

Blast

[Close]

BLAST of TCONS_00021757-protein vs. Swiss-Prot (Human)
Match: ARAP1 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens GN=ARAP1 PE=1 SV=3)

HSP 1 Score: 200.675 bits (509), Expect = 7.683e-52
Identity = 146/404 (36.14%), Postives = 200/404 (49.50%), Query Frame = 0

Query:  325 KKGYLHKKGGQDGKKPPQKRWVEFDGIELKYFKEKGDD-PRQIIPVSRMMDVQAQPDAKKPTFHLLTPNRKFTFFDNNGDLNETSVWMQCLMEAILN-----KPDVPCLVGGQMSD-PDMEGWLLKQGHGVLVQDFKRR-YVAIKDDKLCYYNSFSHFEEDLPIFKLQMSLASLKEDVSRRRLLLSYHTQRTYVFEVPPKDSYEQWKDAIEGSIEKALGDDSVLQILMKDESNLRCADCGTTKNVNWASIKCLVIICKRCCGRHRGYSQKFFLPRSILMDVKIWTNELIEIFKLMGNKNANMLWAAKLPPDEQISPDCSTEERITFLKDKYIHKKYFKLSEHFGLEHELGEALRKAVVTEDLIQTFRLIQSGASVMYIPEESEDKRTPYQLAEDAGQSLQVALL 720
            K G+L K   Q G    QKRWV  D   L+YF    D   ++ I V+ +  V A  D K   F ++T NR F F     D+ E   WMQ L +A+       +     L+G   S+ PD  G L  +G       FK + YVA+  DK+  Y +   +   + I  + MS+ ++KE V RR   L+    R + F    +   EQW +A++G+I +AL    V + +     N  CADCG  +  +WASI   V+ICKRC G HRG        RS+ MD K+WT  LIE+F  +GN   N  WAA +PP E + P  S   R   L+ KY   KY +    FG + EL +AL  AV T DL +T  L+  GA +     + E   TP  LAE AGQ+LQ+  L
Sbjct:  330 KAGWLDKNPPQ-GSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQK---FEVITNNRTFAF-RAESDV-ERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRG-------FKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKE-VDRRSFDLTT-PYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQP-DWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAP-TPLALAEQAGQTLQMEFL 716

HSP 2 Score: 138.658 bits (348), Expect = 9.084e-33
Identity = 140/538 (26.02%), Postives = 236/538 (43.87%), Query Frame = 0

Query:  804 EEVIDLRQMEEIKALDD---QVTFFLQTSSNHSARTYYFKAFTPEDCRSWFTAI-KNKQVFEVALDKQEVSADKIPYLVDKCIKYMETNALTDMKTLTQEGIYRKNGSQAQIRDLTKLFNQDAANVRLDISEYYDVHVICGLLKKYLRDLPEPLVTNILYESFLQNTYEGEIEHNERLYRYRDLIKGLPAINLLCLRALILHLHLVVELSSFNLMTMENVSLLFGPIICSCGRTLNQDKLRLEYK---VLQDLLTYYKWLFDVDENETKSQ-EAILKFTKSAAESTVTPTINEGGMQITIYLKNIEDRMLVDSSTR-PSDVCAFFIKTHDLDRAT-------NWALFESINDGTFERPLSSKESVYDLALSLSDNGKLIVKENYLLEKLAPHQSASFNSG--GVIHFLRDK--------------------SSWKKVYLEIKQGMLRVASSKDSSKDIDKFGIVDAQVLLYSGIDPKKKGPANNKFGFMIKVNGSISNTQPRYFCSDQEEIINMFMAVILNLRYPVGIWTDRCSKDFR 1303
            EE + LR+++E+    D   QV   ++       RT Y +     D   W  AI K        L +Q++    IP +V +C+ Y+    LT       EGIYRK G  ++ + L +   QDA +V L   E + V  +   LK++LRDLP+ L T     ++L+ +     +  E++ RYR+L+  LP +N   ++ALI HL+ V   S  N M + N++++FGP +    +T  QD     YK   V++DL+ +Y  +F VDE E + Q E I    K     T + T + G    T+YL+  E +   +   + P+ + A  +    LDR          W  FE       ERPL   E V  +   L  +  L+VK++  +E +  + ++       G++ F  D+                    SS  ++Y E++       + + S +   ++ I   +V  Y G+  K + P    +GF +         Q  Y C D +  +  + A  L +++   +W    S+  R
Sbjct:  901 EEPLQLRKLQELSIQGDSENQVLVLVERR-----RTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTS------EGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQH-VDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEI--EDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLF---QTDGQD-----YKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLE--EKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPIKSLKV--YLGVKKKLRPPTC--WGFTVVHETEKHEKQQWYLCCDTQMELREWFATFLFVQHDGLVWPSEPSRVSR 1410

The following BLAST results are available for this feature:

BLAST of TCONS_00021757-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00021757-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ARAP1	7.683e-52	36.14	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]

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TCONS_00021757-protein (polypeptide) - C. hemisphaerica