|
|
Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00021941-protein ID=TCONS_00021941-protein|Name=TCONS_00021941-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1806bp
MFLKTNIVCAIWCTMRSVTGTLQILASFYLIINIVKTEDFDKVHMTNSWA
VHIENGNNEIADQVAEKHGFSNVGQIGSLPGYFHFVHKKTGKRSRRKRRD
VTENKTFTLLEDDKVKWVERQHVLERDKRGVVPEYIPTTHAEGYIIRDPL
FSEQWYLNNVGQSNGPSTLDINVLPVWSRGISGKNVVVAILDDGVDHTHP
DLKANYDPRASYDFVDYDNDPRPRDSDPNNCHGTKCAGEVAAEAGNDICG
VGVAFNSSIAGIRMLDGNVTDTIEGSALSYKKDYIDIYSCAWGPKDDGKR
FGRPGTLASKALELGVKEGRQGLGSIFVWATGNGGLTDDDCNCDGYTTSV
YTISIGAISDHGLSTYYTESCSSTLGVTFSGGSHREKKENKIITTTLHHE
CTDEFKGTSSAAPLAAGMIALMLEANSKLGWRDVQHIIVETALMTSPLDE
GWRRNGAGKWFNQKFGFGRLDASAMVDRANNWRNVGEQRACWGDTSVGPW
DIPDSGTLLTSSNATACEGSNSAVKTLEHVQVIITLRHRHRGHVSIELIS
PSGTRTRLLKTRRNDKSTKGLKDWIFMSVHFWGEDPHGIWTLAITDNSHN
NRQHHRYKSRFGDTEDATEILHDEMNGEAHGEDFNTAEQFEDSVFKDDSF
KKKRKDTPPKSMNILNALKQAKAKRIHERNSKKIHKEHHKIKIKGPSHAK
NVTNEGKSDATENDVEAKILEEILGSTQTRDSSNPSSGIMNSTLSMPSQK
PPNTTLSGSHSHNETLNSMVNATQETPPHEETSTSSQGQESTGGDSETKM
LESLLRNVISQVFSNFLNTNNEGSKSFEERISLLEKLLGKKPEEEDDPVI
SGLMNAFKKGKAIDRVNNVLNILQDSKNNTKFTNTSFERNADVVVDVLKV
LKDVLNTGKGDTHMKNYKERVSDLLEKQSGNTEKLTKKLLTDLKQSGTDS
SDVVNDALALISRIFQSEKMKSNKRNKHPKITKNAGKSPHKYRIMFEGPN
SEIELPYSSIKNMFAAANGNNQKEITKTKQTKEIQHDANDVEKITVERVK
VKDHPPSSSSGKRYPTYSTTVRNSMQNTDSSLEMPFPDEGREAPVKSSVP
DGFTLTIEKNGETVGEQKVNNEQAIRMLQSKDSTQSIADLETGDKKHSIK
NKAANNIDVEVIVDGREDPAKAKAKTKDKIDDKPKTIKLQLDNNLIPQSV
SYDAAKKKTHVTNSSKAKSKKSHSSGAKKKTLGKKGKHVTRNNATLAAVQ
ERKPEEEEPIFPFLTFNENEQNFPGNLGENFVPSFNANEFPSFEYPYLPI
PPAYSSNEKASFTQHHNNGNFEAPVRNPSFSIDKRSRLMSYGDYNRMPWP
YYPFVQPTRSSSVPLVRNYRSTRNDDEDLPNNNDNFDTFDEEWEENAKRM
KRHLDDNDEFDFFDSDNEKFKDRPVDNFSLNGKQKRHANDELFEVEGYRN
DINHVFSSRRSSTEEPAHNEPEHEDNKGLHSRKTRSHHGQLRHDKDILRQ
FNHKNENTRRQKRETLSDDDDDVSEVVKHDESELTQLLHDSTPTVESHHS
RRHRRSLDDEKADTNNDDKIDKSKVAQILHDFTRSVKSTDIKDEAGQSRQ
KRSLVNDDSNASLIRQKRNEIDDNDDYDNNDDDDDEGQGPHVVKRSAIFG
QTQPDYVMTTSEKRSAIRKALALEKSLKKKLFSMKKESSSALDIIKRVHT
DISNADAKDLRMLEKELSNMGASATDSNNEEMHDSSVASSERNAEDSSEP
INNFIKLVEQTENSSTRKTIPPTSDEGRKQSSEEYYKYGTSASGVLVSWT
IRFYGT Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006508 | proteolysis |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004252 | serine-type endopeptidase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006508 |
proteolysis |
| molecular_function |
GO:0004252 |
serine-type endopeptidase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR015500 | Peptidase S8, subtilisin-related | PRINTS | PR00723 | SUBTILISIN | coord: 228..241
score: 51.34
coord: 183..202
score: 47.66
coord: 406..422
score: 54.29 |
| IPR000209 | Peptidase S8/S53 domain | PFAM | PF00082 | Peptidase_S8 | coord: 183..468
e-value: 7.3E-47
score: 160.0 |
| IPR000209 | Peptidase S8/S53 domain | GENE3D | 3.40.50.200 | | coord: 137..480
e-value: 1.2E-69
score: 234.1 |
| IPR000209 | Peptidase S8/S53 domain | SUPERFAMILY | 52743 | Subtilisin-like | coord: 145..482 |
| IPR008979 | Galactose-binding domain-like | GENE3D | 2.60.120.260 | | coord: 481..611
e-value: 5.2E-39
score: 132.6 |
| IPR008979 | Galactose-binding domain-like | SUPERFAMILY | 49785 | Galactose-binding domain-like | coord: 477..602 |
| IPR002884 | Proprotein convertase, P | PFAM | PF01483 | P_proprotein | coord: 527..601
e-value: 6.7E-25
score: 86.9 |
| None | No IPR available | GENE3D | 3.30.70.850 | | coord: 35..129
e-value: 7.5E-26
score: 90.0 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1590..1641 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1200..1254 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1051..1101 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 676..797 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1458..1572 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1720..1782 |
| IPR032815 | Peptidase S8, pro-domain | PFAM | PF16470 | S8_pro-domain | coord: 48..129
e-value: 3.2E-24
score: 85.4 |
| IPR023827 | Peptidase S8, subtilisin, Asp-active site | PROSITE | PS00136 | SUBTILASE_ASP | coord: 188..199 |
| IPR023828 | Peptidase S8, subtilisin, Ser-active site | PROSITE | PS00138 | SUBTILASE_SER | coord: 407..417 |
| IPR022398 | Peptidase S8, subtilisin, His-active site | PROSITE | PS00137 | SUBTILASE_HIS | coord: 232..242 |
| IPR034182 | Kexin/furin catalytic domain | CDD | cd04059 | Peptidases_S8_Protein_convertases_Kexins_Furin-like | coord: 148..442
e-value: 2.15065E-155
score: 478.978 |
| IPR009020 | Protease propeptides/proteinase inhibitor I9 | SUPERFAMILY | 54897 | Protease propeptides/inhibitors | coord: 46..121 |
Blast
BLAST of TCONS_00021941-protein vs. Swiss-Prot (Human)
Match: NEC1 (Neuroendocrine convertase 1 OS=Homo sapiens GN=PCSK1 PE=1 SV=2) HSP 1 Score: 533.102 bits (1372), Expect = 2.137e-169 Identity = 275/588 (46.77%), Postives = 372/588 (63.27%), Query Frame = 0
Query: 17 SVTGTLQILASFYLIINIVKTEDFDKVHMTNSWAVHIENGNNEIADQVAEKHGFSNVGQIGSLPGYFHFVHKKTGKRSRRKRRDVTENKTFTLLEDDKVKWVERQHVLERDKRGVVPEYIPTTHAEGYIIRDPLFSEQWYLNNVGQSNGPSTLDINVLPVWSRGISGKNVVVAILDDGVDHTHPDLKANYDPRASYDFVDYDNDPRPR-DSDPNNCHGTKCAGEVAAEAGNDICGVGVAFNSSIAGIRMLDGNVTDTIEGSALSYKKDYIDIYSCAWGPKDDGKRFGRPGTLASKALELGVKEGRQGLGSIFVWATGNGGLTDDDCNCDGYTTSVYTISIGAISDHGLSTYYTESCSSTLGVTFSGGSHREKKENKIITTTLHHECTDEFKGTSSAAPLAAGMIALMLEANSKLGWRDVQHIIVETALMTSPL--DEGWRRNGAGKWFNQKFGFGRLDASAMVDRAN--NWRNVGEQRAC-WGDTSVGPWDIPDSGTLLTSSNATACEGSNSAVKTLEHVQVIITLRHRHRGHVSIELISPSGTRTRLLKTRRNDKSTKGLKDWIFMSVHFWGEDPHGIWTLAITDNS 598
S+ T +L + +N K K N WA I G E A +AE+ G+ +GQIGSL ++ F HK +RSRR +T+ L +DD+V W E+Q+ ER KR + + + + DP++++QWYL + + LD++V+PVW +GI+GK VV+ +LDDG++ H D+ ANYDP ASYDF D D+DP PR D N HGT+CAGE+A +A N CGVGVA+NS + GIRMLDG VTD IE S++ + ++DIYS +WGP DDGK PG LA KA E GVK+GRQG GSIFVWA+GNGG D+C+CDGYT S+YTISI + S GLS +Y E CSSTL ++S G + ++ +I + LH++CT+ GTS++APLAAG+ AL LEAN L WRD+QH++V T+ PL + GW++NGAG N +FGFG L+A A+VD A+ WR+V E++ C D P + +G ++ ACEG +A+K+LEHVQ T+ + RG + + L S +GT T LL R D S G K+W FMSVH WGE+P G WTL ITD S
Sbjct: 7 SLQCTAFVLFCAWCALNSAKA----KRQFVNEWAAEIPGGP-EAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKR----LSDDDRVIWAEQQYEKERSKRSALRD------SALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQ---RITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTS-EYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMS 575
The following BLAST results are available for this feature:
|
