TCONS_00022957-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022957-protein
Unique NameTCONS_00022957-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length848

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022957-protein ID=TCONS_00022957-protein|Name=TCONS_00022957-protein|organism=Clytia hemisphaerica|type=polypeptide|length=848bp
MGKSLGKSYEVDEARLEKGENKADNTQNVIELANRFMDIVHETRPSFPMQ
LQSLCHCLHKAVQQKFPSHSYGAVSSAFFLRFINPVIMSPHSHGIVNQQV
AASVRRGLTLLSKILQNLANHLHFTKEAHMEVFNGFLENNFHRIHAFFRE
ISTEPRREPQYEETDIDAVDEDEDEDEEIFTTDGDILSLHKLLWHAQEKI
GKYLSVQSDSVTFGRGPYEKLVTLLAHLGPPENQPNQFKSMVGIPRDRLG
SIGWRLEDFMAKYAGRNQEELEQIKNMQLFYVDGKSKAGRPVFYYIARKY
INDQVSDEMLLYHMLLTLQSKRNQIWELVVDFTHSSEQNWFKIETLARAF
VILPESQVTSPQTIYFYNVNSSVKQYAIRCDRIMRPLKNHPRVIIIDKLP
KLYEHIHQDELRLPSSTISLEKDNKVYSASKPSVKGSFLVKIGPQSIQLQ
ACERVKVLTFSCLLNDVFYASEIEKASHQDDVLDLEFTSRRTGLKFVTPQ
AEEIVNSILHVQARWRLSQQDKTKHMASKKMRPKDVPGTLLNMSLINLGN
RDPSLRLAAYNLLCALTTNFSLQINERLWEAKGVCIPANCTLFIKSISEQ
LALREPNMTLEFLDECISCFAKSNDESRNLCLNYMAPWFPNLARYCGLSR
NDPNKLQMMEIVKKLIDLTISNRQNYPFIQASVWANIGKIPDLLDVVLDL
FMKTSTAGGFNSEKAEVLADTSVTLASANVAHVSKKILDKFHTVIDRTRI
SHVESLERHLMWDDIAILARYLLMLSFNDSLDVLQHLPDIFHIVTLLVSS
GPVSLRASIHGLVINSLQSLLTCEMKLSDKTQLLIRKKLEDLSLQKFY
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012907XLOC_012907Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022957TCONS_00022957Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001936RasGAP_dom
IPR001251CRAL-TRIO_dom
IPR023152RasGAP_CS
IPR008936Rho_GTPase_activation_prot
Vocabulary: Biological Process
TermDefinition
GO:0043087regulation of GTPase activity
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0043087 regulation of GTPase activity
biological_process GO:0007165 signal transduction
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001936Ras GTPase-activating proteinSMARTSM00323RasGAP_2coord: 1..239
e-value: 1.8E-7
score: 12.6
IPR001936Ras GTPase-activating proteinPFAMPF00616RasGAPcoord: 21..120
e-value: 3.4E-20
score: 72.5
IPR001936Ras GTPase-activating proteinPROSITEPS50018RAS_GTPASE_ACTIV_2coord: 1..120
score: 30.274
NoneNo IPR availableGENE3D1.10.506.10coord: 140..231
e-value: 3.3E-8
score: 33.5
NoneNo IPR availableGENE3D1.10.506.10coord: 3..139
e-value: 1.5E-34
score: 118.9
IPR001251CRAL-TRIO lipid binding domainPFAMPF13716CRAL_TRIO_2coord: 289..421
e-value: 1.9E-11
score: 44.1
IPR001251CRAL-TRIO lipid binding domainGENE3D3.40.525.10coord: 268..413
e-value: 3.1E-12
score: 46.4
IPR001251CRAL-TRIO lipid binding domainCDDcd00170SEC14coord: 275..411
e-value: 4.86986E-6
score: 45.0686
IPR001251CRAL-TRIO lipid binding domainSUPERFAMILY52087CRAL/TRIO domaincoord: 269..411
IPR023152Ras GTPase-activating protein, conserved sitePROSITEPS00509RAS_GTPASE_ACTIV_1coord: 76..90
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 7..231

Blast
[Close]
BLAST of TCONS_00022957-protein vs. Swiss-Prot (Human)
Match: NF1 (Neurofibromin OS=Homo sapiens GN=NF1 PE=1 SV=2)

HSP 1 Score: 771.926 bits (1992), Expect = 0.000e+0
Identity = 396/866 (45.73%), Postives = 568/866 (65.59%), Query Frame = 0 
Query:    8 SYEVDEARLEKGENKADNTQNVIELANRFMDIVHETRPSFPMQLQSLCHCLHKA---------------------VQQKFPSHSYGAVSSAFFLRFINPVIMSPHSHGIVNQQVAASVRRGLTLLSKILQNLANHLHFTKEAHMEVFNGFLENNFHRIHAFFREISTEPRREPQYEETDIDAVDEDEDEDEEIFTTDGDILSLHKLLWHAQEKIGKYLSVQSDSVTFGRGPYEKLVTLLAHLGPPENQPNQFKSMVGIPRDRLGSIGWRLEDFMAKYAGRNQEELEQIKNMQLFYVDGKSKAGRPVFYYIARKYINDQVSDEMLLYHMLLTLQSKRNQIWELVVDFTHSSEQNWFKIETLARAFVILPESQVTSPQTIYFYNVNSSVKQYAIRCDRIMRPLKNHPRVIIIDKLPKLYEHIHQDELRLPSSTISLEKDNKVY-SASKPSVKGSFL-VKIGPQSIQLQACERVKVLTFSCLLNDVFYASEIEKASHQDD-VLDLEFTSRRTGLKFVTPQAEEIVNSILHVQARWRLSQQDKTKHMASKKMRPKDVPGTLLNMSLINLGNRDPSLRLAAYNLLCALTTNFSLQINERLWEAKGVCIPANCTLFIKSISEQLALREPNMTLEFLDECISCFAKSNDESRNLCLNYMAPWFPNLARYCGLSRNDPNKLQMMEIVKKLIDLTISNRQNYPFIQASVWANIGKIPDLLDVVLDLFMKTSTAGGFNSEKAEVLADTSVTLASANVAHVSKKILDKFHTVIDRTRISHVESLERHLMWDDIAILARYLLMLSFNDSLDVLQHLPDIFHIVTLLVSSGPVSLRASIHGLVINSLQSLLTC-EMKLSDKTQLLIRKKLEDLSLQKFY 848
            S+EVD  RLE  E+  +N +N++++  +F   +  +   FP QL+S+CHCL++A                     V Q+FP +S GAV SA FLRFINP I+SP+  GI++++    + RGL L+SKILQ++ANH+ FTKE HM  FN F+++NF     FF +I++             D    D       F +DG++L+LH+LLW+ QEKIG+YLS   D    GR P++K+ TLLA+LGPPE++P     +       L     + E+FM ++    +EE + +K + +FY  G SKAG P+FYY+AR++   Q++ ++L+YH+LLTL+    + +E+VVD TH+   N FK + L++ FV+ P     +   +Y YN NS V++Y    +R++  LK   R++ ID   KL EHI  ++ +LP++T++LE+D KV+ +A K + K + + +K+G  ++Q+ + ER KVL  S  LND++YASEIE+    D+    L   ++ T L F+  + E IV SI+H++ RW LSQ D        K+RPKDVPGTLLN++L+NLG+ DPSLR AAYNLLCALT  F+L+I  +L E  G+CIPAN TLFI SIS+ LA  EP++TLEFL+ECIS F+KS+ E ++LCL YM PW  NL R+C    +D  + ++  I+ KLI +TI+ +Q YP IQA +W ++G+I DLLDVVLD F+KTS  GG  S KAEV+ADT+V LAS NV  VS K++ +   +ID+T +S   +LE+HLMWDDIAILARY+LMLSFN+SLDV  HLP +FH+VT LV++GP+SLRAS HGLVIN + SL TC ++  S++T+ ++R  L + SL KFY
Sbjct: 1318 SFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIAS-------------DCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKP-----VADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHT--KIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCK-HNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFY 2162
The following BLAST results are available for this feature:
BLAST of TCONS_00022957-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NF10.000e+045.73Neurofibromin OS=Homo sapiens GN=NF1 PE=1 SV=2[more]
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