TCONS_00024617-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00024617-protein
Unique NameTCONS_00024617-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length692

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00024617-protein ID=TCONS_00024617-protein|Name=TCONS_00024617-protein|organism=Clytia hemisphaerica|type=polypeptide|length=692bp
MASNGHTENTASMKRNKSFTELLGDNLTFDVKAEVFLDGHVKSMDQYNQM
HKQSVEDPESFWTKIANQFYWKEKWSGKFMEYNFDVRKGDIFIKFMEGGK
TNICYNVLDRVAQETPDKIAFYWEGNDPANCKTYTYKQLLDEVCKFSNVL
KSKGLKKGDRVALYMPMIIELVVAMLACARIGIIHSIVFAGFSADSLAER
LKDGDCSLLITADYSVRGDKSIDLKTVADNALKECGEDGVDIKMCIVVKN
SSAEGDGTHSPKQKKAKTSVSWNEDVDLWWHDLMTGASNDCQCEWMDAED
PLFILYTSGSTGKPKGVLHTTAGYMLYAATTFKYSFDYHEGEVYWCTADI
GWITGHSYIVYGPMANAATSVMFEGTPLYPDAGRMWAVVEKYKVSKFYTA
PTAIRMLMKFSDDFVKKYDRSSLKVLGTVGEPINPEAWLWYYKIVGEERC
SIVDTFWQTETGGHVIGGMPGATMMKPGSASFPFFGAVPVIMDEDGKEKE
GVEVDQGYLVFKQPWPGLMRTLYGNHSRYQAAYFERFPGYYCAGDGAYRD
KDGYYWITGRIDDLMNVSGHLLSTAQVESAIVEHSSISEAAVVGYPHPVK
GTGIYCFVTPKNGIRFCDALVSELKQKVRTRIGPIATPDVIHEAPGLPKT
RSGKIMRRILRKIAAGQTDIGDTTTLADSTVVDKLFTNRPQQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_013826XLOC_013826Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00024617TCONS_00024617Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR032387ACAS_N
IPR000873AMP-dep_Synth/Lig
IPR011904Ac_CoA_lig
IPR025110AMP-bd_C
IPR020845AMP-binding_CS
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0003987acetate-CoA ligase activity
GO:0016208AMP binding
Vocabulary: Biological Process
TermDefinition
GO:0008152metabolic process
GO:0019427acetyl-CoA biosynthetic process from acetate
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0019427 acetyl-CoA biosynthetic process from acetate
biological_process GO:0008152 metabolic process
molecular_function GO:0003987 acetate-CoA ligase activity
molecular_function GO:0016208 AMP binding
molecular_function GO:0003824 catalytic activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR032387Acetyl-coenzyme A synthetase, N-terminal domainPFAMPF16177ACAS_Ncoord: 47..107
e-value: 3.6E-19
score: 68.3
IPR000873AMP-dependent synthetase/ligasePFAMPF00501AMP-bindingcoord: 109..567
e-value: 4.9E-95
score: 318.5
NoneNo IPR availableGENE3D3.30.300.30coord: 563..687
e-value: 1.5E-20
score: 73.4
NoneNo IPR availableGENE3D3.40.50.980coord: 99..309
e-value: 1.4E-55
score: 187.0
NoneNo IPR availableGENE3D2.30.38.10coord: 474..560
e-value: 3.3E-9
score: 36.2
NoneNo IPR availableGENE3D3.40.50.980coord: 310..473
e-value: 3.2E-35
score: 120.7
NoneNo IPR availableSUPERFAMILY56801Acetyl-CoA synthetase-likecoord: 40..686
IPR011904Acetate-CoA ligaseTIGRFAMTIGR02188TIGR02188coord: 42..686
e-value: 4.9E-277
score: 918.3
IPR011904Acetate-CoA ligaseCDDcd05966ACScoord: 51..678
e-value: 0.0
score: 1097.59
IPR025110AMP-binding enzyme, C-terminal domainPFAMPF13193AMP-binding_Ccoord: 577..654
e-value: 3.5E-22
score: 79.1
IPR020845AMP-binding, conserved sitePROSITEPS00455AMP_BINDINGcoord: 304..315

Blast
[Close]
BLAST of TCONS_00024617-protein vs. Swiss-Prot (Human)
Match: ACSA (Acetyl-coenzyme A synthetase, cytoplasmic OS=Homo sapiens GN=ACSS2 PE=1 SV=1)

HSP 1 Score: 902.894 bits (2332), Expect = 0.000e+0
Identity = 423/675 (62.67%), Postives = 526/675 (77.93%), Query Frame = 0 
Query:   24 GDNLTFDVKAEVFLDGHVKSMDQYNQMHKQSVEDPESFWTKIANQFYWKEKWSGKFMEYNFDVRKGDIFIKFMEGGKTNICYNVLDRVAQETP--DKIAFYWEGNDPANCKTYTYKQLLDEVCKFSNVLKSKGLKKGDRVALYMPMIIELVVAMLACARIGIIHSIVFAGFSADSLAERLKDGDCSLLITADYSVRGDKSIDLKTVADNALKECGEDGVDIKMCIVVKN-SSAE---GDGT-HSPKQKKA--KTSVSWNEDVDLWWHDLMTGASNDCQCEWMDAEDPLFILYTSGSTGKPKGVLHTTAGYMLYAATTFKYSFDYHEGEVYWCTADIGWITGHSYIVYGPMANAATSVMFEGTPLYPDAGRMWAVVEKYKVSKFYTAPTAIRMLMKFSDDFVKKYDRSSLKVLGTVGEPINPEAWLWYYKIVGEERCSIVDTFWQTETGGHVIGGMPGATMMKPGSASFPFFGAVPVIMDEDGKEKEGVEVDQGYLVFKQPWPGLMRTLYGNHSRYQAAYFERFPGYYCAGDGAYRDKDGYYWITGRIDDLMNVSGHLLSTAQVESAIVEHSSISEAAVVGYPHPVKGTGIYCFVTPKNGIRFCDALVSELKQKVRTRIGPIATPDVIHEAPGLPKTRSGKIMRRILRKIAAGQTDIGDTTTLADSTVVDKLFTNR 689
            G   ++    EV    HV S+ +Y ++H++SVE+P  FW  IA +FYWK    G F+ YNFDV KG IFI++M+G  TNICYNVLDR   E    DK+AFYWEGN+P      TY QLL +VC+FSNVL+ +G++KGDRVA+YMPMI ELVVAMLACARIG +HSIVFAGFS++SL ER+ D  CSLLIT D   RG+K ++LK +AD AL++C E G  ++ CIVVK+   AE   GD T  SP  K++     +SWN+ +DLWWH+LM  A ++C+ EW DAEDPLFILYTSGSTGKPKGV+HT  GYMLY ATTFKY FD+H  +V+WCTADIGWITGHSY+ YGP+AN ATSV+FEG P YPD  R+W++V+KYKV+KFYTAPTAIR+LMKF D+ V K+ R+SL+VLGTVGEPINPEAWLWY+++VG +RC IVDTFWQTETGGH++  +PGAT MKPGSA+FPFFG  P I++E    +E     +GYLVFKQPWPG+MRT+YGNH R++  YF++FPGYY  GDG  RD+DGYYWITGRIDD++NVSGHLLSTA+VESA+VEH +++EAAVVG+PHPVKG  +YCFVT  +G  F   L  ELK+++R +IGPIATPD I  APGLPKTRSGKIMRR+LRKIA    D+GD +T+AD +V+  LF++R
Sbjct:   24 GRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNE--SGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHR 696
The following BLAST results are available for this feature:
BLAST of TCONS_00024617-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACSA0.000e+062.67Acetyl-coenzyme A synthetase, cytoplasmic OS=Homo ... [more]
back to top