TCONS_00026153-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00026153-protein
Unique NameTCONS_00026153-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length2080

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00026153-protein ID=TCONS_00026153-protein|Name=TCONS_00026153-protein|organism=Clytia hemisphaerica|type=polypeptide|length=2080bp
MGAHPFKFDKEAWRWNLLYFTLWLLFQGASTLPVSGGHIQMDLPQDLTIS
NQWISLSHWDSSIYKKGLFMSDFEMPSNTTFFVKRSGVYFASLYVHLEQA
TSKDFAIRIHTNQNESYTSIGKSKSKLKVLHLNQILLLNEKQTFTVDVNC
SHLNTISQKTVISIHFISNFAYTLGFIANPNEIQTVKSQDYEQVLVNWNV
MFETSYGFSAATGQYTALESAYYVITVQLTLRNVYGKVMLSLRNDDVRDV
IKEEYFEDLSEIVTMTYSGIHRINIKRNILLSVKTFDCKAIIDKRSVYSV
MRTETIYGYQASYSSHDDKSQKAIIEKNNQIESESEQTLKHWRTFHNHTA
FLKNRAMFQLRKSSLYFVYVQVKMKSIDSPTDLIDVELCIDERTNKYLLS
RQNEGSLWATLAGVFYIQDSQDISIIIHNKSPNPIEIAGDQTSIYISELS
FQTYSSTYAVVPISDEEIHNGSLYPVALTMEATSNFNMVTKAVRNIITIQ
HEGTYHVSLNLYLRNIKEDIEFVVMSRLDGNRMKWDTLSKCITGQTDQCF
VASIMRLKEGQQFMVGASTPLNDVIVKESFFQIIFLRSQDETTKTLQTRM
AKDKNTLAEINPVFKFNDGDNFYLLTLNLILANVSDSHVRVKFDFKLGRL
WKPIKKFQRQLNENQTRVSFTLTEGFYARKGSEIKMEIINLKGGSYIIES
LQTARLMLPKNEEGKARFKHLRVDTRAGVQSVLNFVAPKRKHSNGKYFTV
VNYLKAEKSSTALLMVTLEGHLKCQNHQRHRLKAKILLRKTETTIQGYRE
NLKCNEFVSLHMTGVVVAHVEDSIKVLIETDRSSSFTATRQTTITLLVLK
ENPLKMSPTSDLFLSKSLVTDDTDYDKDIQDTEAGGLYEYLVALERSQNK
RIHFEFSVEKNHQNSRIITKRDTSTSPKLFIFSYQEKKNIRIKILVNLQK
GQQIKYSPQVDDVEIQRRKLYELNLKQLNTIRIDKVHEICHNSNKVSILS
GWRCSDGKHCDHSLHTANNSQTVVINANIFVKARNLKKLEELYIAVAGNV
IKKFSMTSPQPTGANIYLLQASYRIFMKRGERLQLHVRCQNKTNFIQPNS
MVQIYIEAIHKSIVDDSFPVFLVHPSPNYVNRSFIFNYTCEAQVTGQQQH
DVKYSWNKVGYYSHVLHSHLSNGDFHTVSGQPAESGHYFCSAEYQGFSSQ
SQTATLHIYDEDECLILSNTTHRELYNITLQPCHTHAQCINTIGSYMCQC
FDGYQGDGFQCQDLNECDEVDNICGEDSDCFNTVGSYKCQCHKGYEGIDG
KQCKDIDECVRHGPELCQQQTRSNNTFCINTDGGFFCNCTEGFYKKKGLC
IDIDECGRDPYPCHAEATCLNSPPGSYSCECDQGWLGNGTHCEDIDECKQ
PEKYKCAVNATCHNFLGSYRCICDHGFKGEGSDNCEPLGCFPPPGCSGQF
LAKWWRRIPYIEQDEAHEKAEGLFKDILNLIITDICQNCSQILFDMPPAN
NSKEVEDQVEANQTDFGCPMYGSKEQESFRDFPFIPIVESPGVAFFVKDI
KQTSSPLLGSLTGSWPILVMTLLLASVSGIIIWFLDTIQNPDEFPQSFLQ
GSWEGFWWAFITMTTVGYGDKAPRSFSARLFGVFWILVGLVIISTFTATI
TTVLTTTTLTSETKMYGTRVGALNNSEEFRLGVKRNADIQEYNSIREIIQ
ALQRDEIQGALLDTYIAGEYQSDLKEYKLQEILEHVFVYGVVLARDAIQL
ENRMRTFTEQKQSTIYNTISKVIKPLKEIKHGSNTVTESVGLFDSSSSFF
TKTMIFGCILLAFLVIVGLLWDWLWRQQMAKQKAMDSDNRKDSNGGNWSS
TDIIEYQQHAFKSEVTNLREQIASFANTWVNRLNEIENHHEDQLTKVQSW
LSKTNLNKSSGNKRKMSKNSQNDDSLPVLLHFEFPDIMKVELGTPLEILA
GATVREEFPSSFRVQHIMERRLLGKWWPLPCIGAQGNGTKCFVDMPCENF
IKMGFEGSCPIQPGEYKQKIFIPVPKFHVPILLTAGLYRSRVYGWSQDMK
KLWFCGHLTQYIEQKKSVHDKSHKKLISQN
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_014702XLOC_014702Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00026153TCONS_00026153Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000742EGF-like_dom
IPR001881EGF-like_Ca-bd_dom
IPR008983Tumour_necrosis_fac-like_dom
IPR013783Ig-like_fold
IPR013099K_chnl_dom
IPR024731EGF_dom
IPR001320Iontro_rcpt
IPR018097EGF_Ca-bd_CS
IPR000152EGF-type_Asp/Asn_hydroxyl_site
IPR013032EGF-like_CS
IPR007110Ig-like_dom
IPR009030Growth_fac_rcpt_
IPR028996GM2-AP
Vocabulary: Molecular Function
TermDefinition
GO:0005509calcium ion binding
GO:0005515protein binding
GO:0004970ionotropic glutamate receptor activity
GO:0008047enzyme activator activity
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Biological Process
TermDefinition
GO:0006689ganglioside catabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006689 ganglioside catabolic process
cellular_component GO:0016020 membrane
molecular_function GO:0005509 calcium ion binding
molecular_function GO:0008047 enzyme activator activity
molecular_function GO:0004970 ionotropic glutamate receptor activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000742EGF-like domainSMARTSM00181egf_5coord: 1308..1351
e-value: 3.0
score: 16.8
coord: 1397..1436
e-value: 1.1E-4
score: 31.6
coord: 1266..1304
e-value: 0.003
score: 26.8
coord: 1213..1262
e-value: 1.6E-4
score: 31.0
coord: 1355..1393
e-value: 1.7E-4
score: 31.0
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1305..1351
score: 6.714
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1352..1393
score: 18.148
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1263..1304
score: 14.894
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1394..1436
score: 15.129
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1225..1260
score: 11.978
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 1352..1393
e-value: 1.3E-10
score: 51.2
coord: 1305..1351
e-value: 3.4E-4
score: 29.8
coord: 1263..1304
e-value: 3.5E-8
score: 43.2
coord: 1210..1262
e-value: 8.3E-10
score: 48.6
coord: 1394..1436
e-value: 4.8E-10
score: 49.4
IPR001881EGF-like calcium-binding domainPFAMPF07645EGF_CAcoord: 1263..1303
e-value: 5.4E-9
score: 36.0
coord: 1352..1392
e-value: 3.1E-7
score: 30.4
coord: 1305..1345
e-value: 9.4E-6
score: 25.6
coord: 1394..1435
e-value: 1.4E-9
score: 37.8
IPR008983Tumour necrosis factor-like domainGENE3D2.60.120.40coord: 476..592
e-value: 4.3E-4
score: 19.5
IPR008983Tumour necrosis factor-like domainGENE3D2.60.120.40coord: 172..301
e-value: 4.3E-5
score: 22.9
coord: 48..171
e-value: 5.2E-4
score: 19.4
IPR008983Tumour necrosis factor-like domainGENE3D2.60.120.40coord: 326..446
e-value: 0.0036
score: 16.7
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 1117..1206
e-value: 1.2E-4
score: 21.5
NoneNo IPR availableGENE3D2.10.25.10coord: 1266..1288
e-value: 7.9E-9
score: 35.0
NoneNo IPR availableGENE3D2.70.220.10coord: 1921..2065
e-value: 1.2E-10
score: 41.0
NoneNo IPR availableGENE3D1.10.287.70coord: 1551..1780
e-value: 1.2E-25
score: 89.3
NoneNo IPR availableGENE3D2.10.25.10coord: 1313..1333
e-value: 2.1E-7
score: 30.4
coord: 1397..1423
e-value: 1.6E-10
score: 40.4
NoneNo IPR availableGENE3D2.10.25.10coord: 1207..1244
e-value: 4.3E-9
score: 35.6
coord: 1354..1376
e-value: 1.6E-8
score: 33.8
NoneNo IPR availableGENE3D2.10.25.10coord: 1377..1396
e-value: 2.5E-9
score: 36.3
coord: 1424..1495
e-value: 3.4E-5
score: 23.1
NoneNo IPR availableGENE3D2.40.155.10coord: 1289..1312
e-value: 4.2E-13
score: 48.9
coord: 1334..1353
e-value: 3.5E-7
score: 29.4
coord: 1245..1265
e-value: 4.1E-14
score: 52.1
NoneNo IPR availableCDDcd00054EGF_CAcoord: 1210..1262
e-value: 3.38491E-8
score: 51.4834
NoneNo IPR availableCDDcd00054EGF_CAcoord: 1394..1436
e-value: 1.91566E-9
score: 54.9502
NoneNo IPR availableCDDcd00054EGF_CAcoord: 1305..1344
e-value: 4.41969E-7
score: 48.0166
NoneNo IPR availableCDDcd00054EGF_CAcoord: 1352..1393
e-value: 5.50979E-9
score: 53.7946
NoneNo IPR availableCDDcd00054EGF_CAcoord: 1263..1297
e-value: 4.51196E-9
score: 53.7946
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 1564..1654
NoneNo IPR availableSUPERFAMILY53850Periplasmic binding protein-like IIcoord: 1664..1744
coord: 1459..1557
IPR013099Potassium channel domainPFAMPF07885Ion_trans_2coord: 1580..1655
e-value: 6.2E-12
score: 45.2
IPR024731EGF domainPFAMPF12947EGF_3coord: 1232..1261
e-value: 1.2E-8
score: 34.9
IPR001320Ionotropic glutamate receptorPFAMPF00060Lig_chancoord: 1567..1662
e-value: 1.2E-11
score: 44.5
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 1394..1421
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 1263..1289
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 1280..1291
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 1328..1339
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 1412..1423
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 1239..1250
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 1421..1435
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 1289..1303
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 1337..1350
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 1379..1392
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 1119..1207
score: 8.375
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 1317..1444
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 1230..1352
IPR028996Ganglioside GM2 activatorSUPERFAMILY63707Ganglioside M2 (gm2) activatorcoord: 1948..2059

Blast
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BLAST of TCONS_00026153-protein vs. Swiss-Prot (Human)
Match: FBLN4 (EGF-containing fibulin-like extracellular matrix protein 2 OS=Homo sapiens GN=EFEMP2 PE=1 SV=3)

HSP 1 Score: 137.117 bits (344), Expect = 6.154e-34
Identity = 77/217 (35.48%), Postives = 109/217 (50.23%), Query Frame = 0 
Query: 1210 DEDECLILSNTTHRELYNITLQPCHTHAQCINTIGSYMCQCFDGYQGDGFQCQDLNECDEVDNICGEDSDCFNTVGSYKCQCHKGYE-GIDGKQCKDIDECVRHGPELCQQQTRSNNTFCINTDGGFFCNCTEGF--YKKKGLCIDIDECGRDPYPCHAEATCLNSPPGSYSCECDQGWLGNGTH-CEDIDECKQPEKYKCAVNATCHNFLGSYRCI 1422
            D+D C+ +            L  C     C N  GSY C C DGY+  G +C D++EC      C     C N  GS++CQC  G++ G + + C D++EC    P  C+Q+       C N+ G F C C +G+  ++    C DIDEC    Y C  +  C+N  PG +SC C QG+    T  C+DIDEC +   ++C+   TC NF G YRC+
Sbjct:  117 DQDSCVDVDECAQ------ALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYC--QHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP--CEQR-------CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC--QYRCINE-PGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQCSEAQTCVNFHGGYRCV 310

HSP 2 Score: 94.3597 bits (233), Expect = 8.234e-20
Identity = 64/211 (30.33%), Postives = 88/211 (41.71%), Query Frame = 0 
Query: 1249 QCFDGYQ--GDGFQCQDLNECDEVDNICGEDSDCFNTVGSYKC---------------------------QCHKGYEGIDGKQCKDIDECVRHGPELCQQQTRSNNTFCINTDGGFFCNCTEGFYKKKGLCIDIDECGRDPYPCHAEATCLNSPPGSYSCECDQGW-LG-NGTHCEDIDECKQPEKYKCAVNATCHNFLGSYRCICDHGFK 1428
            +C DGY+   D   C+D+NEC  +   C  +  C N  G Y C                            C  GYE  D   C D+DEC +   +    Q       C N  G + C C +G+ K    C+DIDEC R  Y  H    C+N  PGS+ C+C+ G+ LG N   C D++EC             C N  G++ C C  G++
Sbjct:   38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQD------CHNLPGSYQCTCPDGYRKIGPECVDIDEC-RYRYCQH---RCVNL-PGSFRCQCEPGFQLGPNNRSCVDVNECDM----GAPCEQRCFNSYGTFLCRCHQGYE 233
The following BLAST results are available for this feature:
BLAST of TCONS_00026153-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FBLN46.154e-3435.48EGF-containing fibulin-like extracellular matrix p... [more]
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