dishevelled (polypeptide) - C. hemisphaerica

Overview
Namedishevelled
Unique NameTCONS_00027361-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length721

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00027361-protein ID=TCONS_00027361-protein|Name=dishevelled|organism=Clytia hemisphaerica|type=polypeptide|length=721bp
QFSSLPNAFSSTFRVVKEEIIDDDAPLPCFNGRVVSWVVPPEDGSCDGQS
QHSGDGIFVPVQSSNTNISRSSTMRSKERVQDSDAESIVSRRSSRSRSSR
KYESDADRRSRRSHREHRNYDQYDSASMMSSDLETTSFVDSEEESQMSSA
TESSRYVGGNKRRRRRRQRMPRVERCSSFSTITESTMSLNIITVTLNMDK
INFLGISIVGQASKKGDGGIYVGSVMKGGAVDADGRVEPGDMILAVGDVN
FENMSNDDAVRVLRECVHKPGPIQLTVAKCWDPNPKGYFTVPKDDVTRPI
DPAAWVQHSEAMRAGGGLMGRGSPSMSTMTSTSDSFSSSIPEADRYLEHD
LGLTLTIDTDMLTIVKVMNQENSGLTVRDRMWLKITIPNAFIGSDLVDWL
FANVEGFQDRREARKYASKLLKANLIRHTVNKVTFSEQCYYVFGDLSDRR
RGMHMQDIEGSEEDTLAPLASTSAQAQMGGYIQQPYGMAMIPGGVMMAGA
PPTYQQVVQPGMYAQYPYVAGSIAPSHLSGGSGGSGSQKSQKIHDDQATV
RSSGSSDRSHSSKGSRSRKPMLDDRSSLSSFHSDTISLRSEIIAPDNRSI
SSHHSIPPMMVMPPGVAYSAAPVGLTPEQQQHIQVQMHQQQQMHHQIQQQ
LQQLQLQSPAQTPQPPPAGSPQPPQDGTRTPAEQHRELGRLDTLPASLSA
SRQSFRMAMGNSSNEFFVDVM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_015396XLOC_015396Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00027361TCONS_00027361Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR008339Dishevelled_fam
IPR000591DEP_dom
IPR001478PDZ
IPR011991WHTH_DNA-bd_dom
IPR003351Dishevelled_protein_dom
IPR001158DIX
Vocabulary: Biological Process
TermDefinition
GO:0016055Wnt signaling pathway
GO:0035556intracellular signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0016055 Wnt signaling pathway
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 637..657
NoneNo IPR availableGENE3D2.30.42.10coord: 70..281
e-value: 1.9E-19
score: 69.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 639..696
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 528..582
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 44..174
NoneNo IPR availableCDDcd04438DEP_dishevelledcoord: 363..445
e-value: 2.57599E-50
score: 169.446
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 191..278
e-value: 2.41104E-18
score: 79.9182
IPR008339Dishevelled familyPRINTSPR01760DISHEVELLEDcoord: 428..439
score: 90.2
coord: 268..282
score: 80.39
coord: 302..314
score: 55.66
coord: 402..412
score: 63.1
IPR000591DEP domainSMARTSM00049DEP_3coord: 371..445
e-value: 5.6E-28
score: 108.9
IPR000591DEP domainPFAMPF00610DEPcoord: 374..443
e-value: 1.8E-17
score: 63.1
IPR000591DEP domainPROSITEPS50186DEPcoord: 371..445
score: 27.685
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 202..281
e-value: 3.3E-16
score: 69.8
IPR001478PDZ domainPFAMPF00595PDZcoord: 194..277
e-value: 5.4E-18
score: 65.0
IPR001478PDZ domainPROSITEPS50106PDZcoord: 193..265
score: 17.913
IPR001478PDZ domainSUPERFAMILY50156PDZ domain-likecoord: 174..284
IPR011991Winged helix-turn-helix DNA-binding domainGENE3D1.10.10.10coord: 356..664
e-value: 1.4E-26
score: 92.6
IPR011991Winged helix-turn-helix DNA-binding domainSUPERFAMILY46785"Winged helix" DNA-binding domaincoord: 360..459
IPR003351Dishevelled protein domainPFAMPF02377Dishevelledcoord: 70..189
e-value: 4.8E-24
score: 85.5
IPR001158DIX domainPFAMPF00778DIXcoord: 12..39
e-value: 3.1E-6
score: 26.8
IPR001158DIX domainPROSITEPS50841DIXcoord: 1..42
score: 13.734

Blast
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BLAST of dishevelled vs. Swiss-Prot (Human)
Match: DVL1 (Segment polarity protein dishevelled homolog DVL-1 OS=Homo sapiens GN=DVL1 PE=1 SV=2)

HSP 1 Score: 403.675 bits (1036), Expect = 4.792e-131
Identity = 243/483 (50.31%), Postives = 310/483 (64.18%), Query Frame = 0 
Query:   13 FRVVKEEIIDDDAPLPCFNGRVVSWVVPPEDGSCDGQSQHSGDGIFVPVQSSNT-------------NISRSSTMRSKERVQDSDAESIVSRRSSRSRSSRKYESDADRRSRRSHREHRNYDQYDSASMMSSDLETTS-FVDSEEESQMS-----SATESSRYVGGNKRRRRRRQRMPRVERCSSFSTITESTMSLNIITVTLNMDKINFLGISIVGQASKKGDGGIYVGSVMKGGAVDADGRVEPGDMILAVGDVNFENMSNDDAVRVLRECVHKPGPIQLTVAKCWDPNPKGYFTVPKDDVTRPIDPAAWVQHSEAMRAGGGLMGRGSPSMSTMTSTSDSFSSSIPEADRYLEHDLGLTLTIDTDMLTIVKVMNQENSGLTVRDRMWLKITIPNAFIGSDLVDWLFANVEGFQDRREARKYASKLLKANLIRHTVNKVTFSEQCYYVFGDLSDRRRGMHMQDIEG--SEEDTLAPLASTSA 474
            F VVKEEI DD+A LPCFNGRVVSW+V  E    D  SQ +     +P     T             N++ S      E    +  ES+VS R  R+R   + E+       R  R        DSAS   S    +S FVDS+E+   S     +   +S  +    +RRRR+QR+ + +R SSFS+IT+STMSLNI+TVTLNM++ +FLGISIVGQ++ +GDGGIY+GS+MKGGAV ADGR+EPGDM+L V DVNFENMSNDDAVRVLRE V + GPI LTVAKCWDP P+ YFTVP+ D  RPIDPAAW+ H+ A+       G    S +   ++S S +SS+P A +  E      LT+ +DM  +V+VM   +SGL +RDRMWLKITI NA IG+D+VDWL+ +VEGF++RREARKYAS LLK   +RHTVNK+TFSEQCYYVFGDL      +++       S++DTLAPL   +A
Sbjct:   56 FGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNE----TGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEE----APLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAA 530
The following BLAST results are available for this feature:
BLAST of dishevelled vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
DVL14.792e-13150.31Segment polarity protein dishevelled homolog DVL-1... [more]
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