TCONS_00060248-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00060248-protein
Unique NameTCONS_00060248-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length455

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00060248-protein ID=TCONS_00060248-protein|Name=TCONS_00060248-protein|organism=Clytia hemisphaerica|type=polypeptide|length=455bp
MFTIIPLTSQLFFNWKSMKLQALCWSFLLSWLQFAVGLKMSNTPREESIH
TELFTNYNANVKPDGLINNTVQVHLDVTVLKLSFLDIRSQVLSIQTFTTL
RWFDKRLMWDPKAHHDITQISVPNSLLWTPDIVLYNDADNDYTTHNEIYR
TNVQIHHKGMLTWTSNIEWKANCEVDITWFPLDKQVCNLLYGSLSYTSEQ
LSLVLREKVRNIDGFVKRGDRNFVQSGEWDVKDINIKSVEQKFPCCRDNF
SALSYTVALSRFPQFYFLYMFFPIFSQFFLFLMVFHIRPESGERLGFGIT
ILLNITMFMTFISEKLPEKSNNRPLIGLLFSVLFFIYSLGLALASMTTFF
SSRLGPVPHWLRKFAAPAATEEAFIVENQTSENIEDEEINTTKDGPKIQT
ISRGSNSEVTWAMVMRSLDKYLFYIFLVISVLLPIIIGLSLDQNFFAGWK
NIFNV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037898XLOC_037898Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00060248TCONS_00060248Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 126..137
score: 47.4
coord: 93..109
score: 28.83
coord: 173..187
score: 46.33
coord: 257..269
score: 26.14
NoneNo IPR availableGENE3D1.20.58.390coord: 267..442
e-value: 4.6E-22
score: 77.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 47..261
e-value: 1.6E-46
score: 158.4
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 41..266
e-value: 5.4E-52
score: 175.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 45..261
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 279..387
e-value: 3.6E-14
score: 53.3
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 263..438
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 173..187

Blast
BLAST of TCONS_00060248-protein vs. Swiss-Prot (Human)
Match: ACHA9 (Neuronal acetylcholine receptor subunit alpha-9 OS=Homo sapiens GN=CHRNA9 PE=1 SV=2)

HSP 1 Score: 178.333 bits (451), Expect = 1.517e-50
Identity = 104/347 (29.97%), Postives = 177/347 (51.01%), Query Frame = 0
Query:   24 CWSFLLSWLQFAV----GLKMSNTPREESIHTELFTNYNANVKPDGLINNTVQVHLDVTVLKLSFLDIRSQVLSIQTFTTLRWFDKRLMWDPKAHHDITQISVPNSLLWTPDIVLYNDADNDYTTHNEIYRTNVQIHHKGMLTWTSNIEWKANCEVDITWFPLDKQVCNLLYGSLSYTSEQLSLVLREKVRNIDGFVKRGD-RNFVQSGEWDVKDINIKSVEQKFPCCRDNFSALSYTVALSRFPQFYFLYMFFPIFSQFFLFLMVFHIRPESGERLGFGITILLNITMFMTFISEKLPEKSNNRPLIGLLFSVLFFIYSLGLALASMTT---FFSSRLGPVPHWLR 362
            C SF   W+ FA       + ++    + +  +LF +Y+  ++P    +  + V L +T+ ++  +D R+Q+L+   +    W D  L WD   +  +  I +P+ L+W PDIVLYN AD++    +E   TNV + + G++TW +    K++C VD+T+FP D Q CNL +GS +Y   Q+         +I   +  GD  +F++  EW+V  +        + CC + +  +++T+ L R   FY + +  P     FL  + F++   SGE++  G+TILL +T+F   ++E +P  S N PLIG  +     + +   AL  M     F  +   PVPHW R
Sbjct:    7 CISF--CWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE---SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV---------DIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAR 338          
The following BLAST results are available for this feature:
BLAST of TCONS_00060248-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA91.517e-5029.97Neuronal acetylcholine receptor subunit alpha-9 OS... [more]
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