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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00061299-protein ID=TCONS_00061299-protein|Name=TCONS_00061299-protein|organism=Clytia hemisphaerica|type=polypeptide|length=511bp
MSGLKRGNNISSSDYVKLRRISDTNDILLSNSDATISMDTAAFGSSSLYP
TGGNCQICEDKATGKHYGAISCDGCKGFFRRSIRKNQNYSCRFSKDCKIS
KDNRNQCRYCRLRKCIRVGMKKEAVQNERDKITRKPAEEAERVLSPQTLV
SAEMLSRPSHSTNEMMMEGREATSNDIVESMKQQLLVLVEWAKYIPVFCE
LPLDDQVSLLRAHASEHLVLGVARRSIMYKDALLLGNDLVISRAHPEPEI
RRIAVKVVDEIVKPMVELDVDETEYACLKAIVFFNPDARGLSNTKKVKQL
RFEVQTSLEEYINERSFDCRGKFGEMLLLLPTLQSSAANMVEQLQFARLF
GVARVDNLLQEMLLGGSGVQDQLDALAMPQSPTEMEQQAAQAAVPGGSNA
SGVATTTSGTTGASTAGGGGPGCQQCMGLSQLSFAASQLTPATVQNSLNL
LENRNLSQTLSSFNAAGNVSSATGGQPVTIQDGALTGASSLGXGDGRPTC
YNPGWRVDWRQ Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0043565 | sequence-specific DNA binding |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding |
| GO:0008270 | zinc ion binding |
| GO:0003677 | DNA binding |
| GO:0003707 | steroid hormone receptor activity |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006355 | regulation of transcription, DNA-templated |
| GO:0043401 | steroid hormone mediated signaling pathway |
Vocabulary: Cellular Component
| Term | Definition |
|---|
| GO:0005634 | nucleus |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006355 |
regulation of transcription, DNA-templated |
| biological_process |
GO:0043401 |
steroid hormone mediated signaling pathway |
| cellular_component |
GO:0005634 |
nucleus |
| molecular_function |
GO:0003677 |
DNA binding |
| molecular_function |
GO:0043565 |
sequence-specific DNA binding |
| molecular_function |
GO:0003707 |
steroid hormone receptor activity |
| molecular_function |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
| molecular_function |
GO:0008270 |
zinc ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR001628 | Zinc finger, nuclear hormone receptor-type | PRINTS | PR00047 | STROIDFINGER | coord: 112..120
score: 59.56
coord: 71..86
score: 62.02
coord: 55..71
score: 51.07
coord: 104..112
score: 62.02 |
| IPR001628 | Zinc finger, nuclear hormone receptor-type | SMART | SM00399 | c4gold | coord: 52..123
e-value: 7.4E-40
score: 148.4 |
| IPR001628 | Zinc finger, nuclear hormone receptor-type | PFAM | PF00105 | zf-C4 | coord: 54..122
e-value: 1.3E-30
score: 105.5 |
| IPR001628 | Zinc finger, nuclear hormone receptor-type | PROSITE | PS00031 | NUCLEAR_REC_DBD_1 | coord: 55..81 |
| IPR001628 | Zinc finger, nuclear hormone receptor-type | PROSITE | PS51030 | NUCLEAR_REC_DBD_2 | coord: 52..127
score: 21.307 |
| IPR000003 | Retinoid X receptor/HNF4 | PRINTS | PR00545 | RETINOIDXR | coord: 297..316
score: 35.56
coord: 256..274
score: 35.66
coord: 123..136
score: 44.51 |
| IPR001723 | Nuclear hormone receptor | PRINTS | PR00398 | STRDHORMONER | coord: 180..201
score: 38.55
coord: 201..217
score: 46.01
coord: 325..342
score: 27.78
coord: 116..126
score: 51.52
coord: 268..283
score: 42.39 |
| IPR000536 | Nuclear hormone receptor, ligand-binding domain | SMART | SM00430 | holi | coord: 179..337
e-value: 1.6E-46
score: 170.5 |
| IPR000536 | Nuclear hormone receptor, ligand-binding domain | PFAM | PF00104 | Hormone_recep | coord: 164..350
e-value: 1.0E-39
score: 136.2 |
| IPR000536 | Nuclear hormone receptor, ligand-binding domain | SUPERFAMILY | 48508 | Nuclear receptor ligand-binding domain | coord: 121..363 |
| None | No IPR available | GENE3D | 1.10.565.10 | | coord: 115..365
e-value: 7.6E-74
score: 247.9 |
| None | No IPR available | CDD | cd06960 | NR_DBD_HNF4A | coord: 55..130
e-value: 2.28454E-46
score: 156.196 |
| None | No IPR available | CDD | cd06931 | NR_LBD_HNF4_like | coord: 145..362
e-value: 7.64232E-126
score: 368.626 |
| None | No IPR available | SUPERFAMILY | 57716 | Glucocorticoid receptor-like (DNA-binding domain) | coord: 54..136 |
| IPR013088 | Zinc finger, NHR/GATA-type | GENE3D | 3.30.50.10 | | coord: 50..114
e-value: 7.3E-33
score: 112.1 |
Blast
BLAST of TCONS_00061299-protein vs. Swiss-Prot (Human)
Match: HNF4G (Hepatocyte nuclear factor 4-gamma OS=Homo sapiens GN=HNF4G PE=1 SV=3) HSP 1 Score: 421.009 bits (1081), Expect = 1.637e-144 Identity = 204/320 (63.75%), Postives = 249/320 (77.81%), Query Frame = 0
Query: 55 CQICEDKATGKHYGAISCDGCKGFFRRSIRKNQNYSCRFSKDCKISKDNRNQCRYCRLRKCIRVGMKKEAVQNERDKI-TRKPAEEAERVLSPQTLVSAEMLSR------PSHSTNEMMMEGREATSNDIVESMKQQLLVLVEWAKYIPVFCELPLDDQVSLLRAHASEHLVLGVARRSIMYKDALLLGNDLVISRAHPEPEIRRIAVKVVDEIVKPMVELDVDETEYACLKAIVFFNPDARGLSNTKKVKQLRFEVQTSLEEYINERSFDCRGKFGEMLLLLPTLQSSAANMVEQLQFARLFGVARVDNLLQEMLLGGS 367
C IC D+ATGKHYGA SCDGCKGFFRRSIRK+ YSCRFS+ C + KD RNQCRYCRLRKC R GMKKEAVQNERD+I TR+ + + S TL AE+ SR P ST+ + + A+ D+ ESMKQQLLVLVEWAKYIP FCELPLDDQV+LLRAHA EHL+LG +RS+MYKD LLLGN+ VI R E EI R+A +V+DE+V+P E+ +D+ EYACLKAIVFF+PDA+GLS+ K+K +RF+VQ LE+YIN+R +D RG+FGE+LLLLPTLQS M+EQ+QF +LFG+ ++DNLLQEMLLGG+
Sbjct: 12 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTD--INVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGA 329
The following BLAST results are available for this feature:
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