TCONS_00011435-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00011435-protein
Unique NameTCONS_00011435-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length325

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00011435-protein ID=TCONS_00011435-protein|Name=TCONS_00011435-protein|organism=Clytia hemisphaerica|type=polypeptide|length=325bp
MSQFKRVFIGRPIIKEAVDIIKNAGFEVDMWEERLILPTEDEMCERSKGV
HGLYTLGPQKVTKKILDAAGDQLKVVSAMSVGVDAIDLVELKSRGIRLGH
TPGVLTDAVAELAVGLLLSTSRRIIEQAHVAKSGHWSTWDPFGDLGCGLR
NSTVGIVGLGRIGSAVARRLVPFGVSKIVYNSRSEKPEAKEFNAQYLSFD
ELLAVSDFVICCCSMNDSSKELFNESAFSKMKSSAILVNIGRGGMVDQNA
LVKALQNNQIRGAGLDVTTPEPLPKEHPLYQFPNVCILPHIGSAEIQTRT
DMATMAARNLVAALTGEKMPAEYPL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006416XLOC_006416Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00011435TCONS_00011435Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006140D-isomer_DH_NAD-bd
IPR006139D-isomer_2_OHA_DH_cat_dom
IPR016040NAD(P)-bd_dom
Vocabulary: Molecular Function
TermDefinition
GO:0051287NAD binding
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0008152metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008152 metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0051287 NAD binding
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domainPFAMPF028262-Hacid_dh_Ccoord: 114..292
e-value: 4.7E-57
score: 192.1
IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainPFAMPF003892-Hacid_dhcoord: 9..320
e-value: 2.2E-27
score: 95.2
NoneNo IPR availableGENE3D3.40.50.720coord: 115..294
e-value: 1.3E-54
score: 184.3
NoneNo IPR availableGENE3D3.40.50.720coord: 1..114
e-value: 2.2E-25
score: 88.5
NoneNo IPR availableCDDcd05301GDHcoord: 5..316
e-value: 6.06018E-156
score: 441.063
NoneNo IPR availableSUPERFAMILY52283Formate/glycerate dehydrogenase catalytic domain-likecoord: 5..142
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 108..292

Blast
BLAST of TCONS_00011435-protein vs. Swiss-Prot (Human)
Match: GRHPR (Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens GN=GRHPR PE=1 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 1.175e-103
Identity = 160/325 (49.23%), Postives = 212/325 (65.23%), Query Frame = 0
Query:    3 QFKRVFIGRPIIKEA-VDIIKNAGFEVDMWEERLILPTEDEMCERSKGVHGLYTLGPQKVTKKILDAAGDQLKVVSAMSVGVDAIDLVELKSRGIRLGHTPGVLTDAVAELAVGLLLSTSRRIIEQAHVAKSGHWSTWDPFGDLGCGLRNSTVGIVGLGRIGSAVARRLVPFGVSKIVYNSRSEKP-EAKEFNAQYLSFDELLAVSDFVICCCSMNDSSKELFNESAFSKMKSSAILVNIGRGGMVDQNALVKALQNNQIRGAGLDVTTPEPLPKEHPLYQFPNVCILPHIGSAEIQTRTDMATMAARNLVAALTGEKMPAEYPL 325
            +  +VF+ R I  E  V + + A  EV+ W+    +P + E+     G HGL  L    V K+ILDAAG  LKV+S MSVG+D + L E+K RGIR+G+TP VLTD  AELAV LLL+T RR+ E     K+G W++W P    G GL  STVGI+GLGRIG A+ARRL PFGV + +Y  R  +P EA EF A+++S  EL A SDF++  CS+  +++ L N+  F KMK +A+ +NI RG +V+Q+ L +AL + +I  AGLDVT+PEPLP  HPL    N  ILPHIGSA  +TR  M+ +AA NL+A L GE MP+E  L
Sbjct:    5 RLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAK-ELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL 328          
The following BLAST results are available for this feature:
BLAST of TCONS_00011435-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GRHPR1.175e-10349.23Glyoxylate reductase/hydroxypyruvate reductase OS=... [more]
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