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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00011884-protein ID=TCONS_00011884-protein|Name=TCONS_00011884-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1086bp
MTDVDSTLVGNDTEIEEFVENERLLQSSELDEHTRIGEETKDALTEKIIE
LFHFCDVENKGYVVKEDLYRLRDELGLEFSDIDHAFEQLDTNKDSFLSMD
EFTTGFGLFIGVERPNHTADLPAEGAENDEGIQIDFSFQVFNLIDKDDKG
HITKNDLIESADTLEIDSSQIDYVYQRLRGVSSDKIYFEDFVNNIGSIVA
LSPALQEIKESNEQQQKGNDRIAIIERVFKMDLSSYEEDDVERLLHEQAT
ILFKRCDYGNKNYVTREDLLTLASELDLSTDQVTEAFDKLNINNRDYLTL
REFINGFGVFLGLENEQMDLRNGGVDGVDEVILENAELEKAAELFNACDI
NNRGYVSLYDLKQLTNKLDLSETQISDIFRQLDDDDNGFITLNEFVNGFS
HFMDATSENNNHAKESPRLLKEKSMDEIYFTDSTTHAPVSGKPRLQSSGI
PHDYLERSDSQTSRGSRGSERSFITRQMSIRYETGSTEIDDMLDSIENEF
GSAVSKDQLQDIWNTVSFSGDPNTTKVFESFLGKVYNELRTARQETKHLE
NVLERKSQVHQEEMKKIYDEVEIQMQTEKLKQTQQLAEKETVLREDMLRE
LKEKEGQIEKMIQRENTLANRLSNVKEQEQSLKHQNSKLMKENMQLEDQL
NDSMSNLSYLKTNLQHMEEQTTAEKKETLKAAVQATQGIQSEHESLIKQL
DLLRSMNQKLRDERDSLELSIRSKTSRLDDIDGIEDSIPAKKPISRHGSN
IGKYIQERSSSTPTHSPLSKQGSIMSNYFEPLGDHRHSSFSENLDAQLSR
IGEGEVDTSVFDSVIEMDEPSSNEALIIDTHQQSVNNEPDLGSQTSSSPA
PSSPRQEPVGMNNDEEHFSDNISSVSHSTAPVETPSRVYKCVFVGDSGVG
KSSFIHRFCFDEFQKNFSATIGVDMHVKTIKVKRQWVALQLWDTAGQERF
RSITKNYFRRADGVIVMFDVTSETSFLNVKGWMLNIEEGAEPDCQIMLLG
NKKDLCDNHPKKRKITPEMAQTLADSFGATYYEVSALSGTGVLESIDHLA
TRMALNEDGLMQKSVIDIHKYCNAEGANGEKKKCCR Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005509 | calcium ion binding |
| GO:0005525 | GTP binding |
| GO:0003924 | GTPase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| molecular_function |
GO:0005509 |
calcium ion binding |
| molecular_function |
GO:0003924 |
GTPase activity |
| molecular_function |
GO:0005525 |
GTP binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 693..727 |
| None | No IPR available | COILS | Coil | Coil | coord: 361..381 |
| None | No IPR available | COILS | Coil | Coil | coord: 594..656 |
| None | No IPR available | PRINTS | PR00449 | RASTRNSFRMNG | coord: 912..928
score: 28.64
coord: 992..1005
score: 47.0
coord: 1031..1053
score: 26.85
coord: 889..910
score: 45.5
coord: 930..952
score: 46.65 |
| None | No IPR available | SMART | SM00176 | ran_sub_2 | coord: 894..1084
e-value: 8.3E-10
score: 48.6 |
| None | No IPR available | SMART | SM00173 | ras_sub_4 | coord: 886..1056
e-value: 2.6E-15
score: 66.9 |
| None | No IPR available | SMART | SM00174 | rho_sub_3 | coord: 891..1057
e-value: 5.0E-14
score: 59.3 |
| None | No IPR available | SMART | SM00175 | rab_sub_5 | coord: 889..1056
e-value: 1.1E-60
score: 217.6 |
| None | No IPR available | GENE3D | 3.30.70.1390 | | coord: 887..952
e-value: 7.0E-27
score: 92.7 |
| None | No IPR available | GENE3D | 1.10.238.10 | | coord: 213..322
e-value: 3.7E-8
score: 32.4
coord: 328..428
e-value: 4.1E-15
score: 54.9 |
| None | No IPR available | GENE3D | 1.10.238.10 | | coord: 150..212
e-value: 8.1E-4
score: 18.9 |
| None | No IPR available | GENE3D | 1.10.238.10 | | coord: 29..93
e-value: 3.9E-8
score: 32.6 |
| None | No IPR available | GENE3D | 1.10.238.10 | | coord: 94..149
e-value: 6.4E-6
score: 25.4 |
| None | No IPR available | GENE3D | 3.40.50.300 | | coord: 953..1054
e-value: 3.5E-28
score: 97.0 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 757..777 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 835..879 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 433..473 |
| None | No IPR available | PROSITE | PS51419 | RAB | coord: 884..1085
score: 29.302 |
| None | No IPR available | CDD | cd00154 | Rab | coord: 889..1051
e-value: 5.85053E-67
score: 221.561 |
| IPR002048 | EF-hand domain | SMART | SM00054 | efh_1 | coord: 47..75
e-value: 110.0
score: 1.4
coord: 340..368
e-value: 4.3
score: 12.7
coord: 81..109
e-value: 0.78
score: 18.6
coord: 374..402
e-value: 0.023
score: 23.9
coord: 282..310
e-value: 61.0
score: 3.4
coord: 136..164
e-value: 51.0
score: 4.0 |
| IPR002048 | EF-hand domain | PFAM | PF13202 | EF-hand_5 | coord: 83..104
e-value: 0.046
score: 13.2 |
| IPR002048 | EF-hand domain | PFAM | PF13499 | EF-hand_7 | coord: 339..398
e-value: 3.5E-8
score: 33.7 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 336..364
score: 5.531 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 132..167
score: 9.911 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 77..112
score: 9.939 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 278..313
score: 7.121 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 370..405
score: 12.7 |
| IPR002048 | EF-hand domain | CDD | cd00051 | EFh | coord: 340..400
e-value: 2.05098E-6
score: 45.6165 |
| IPR005225 | Small GTP-binding protein domain | TIGRFAM | TIGR00231 | TIGR00231 | coord: 889..1047
e-value: 1.1E-22
score: 78.5 |
| IPR001806 | Small GTPase superfamily | PFAM | PF00071 | Ras | coord: 890..1053
e-value: 7.7E-50
score: 168.6 |
| IPR018247 | EF-Hand 1, calcium-binding site | PROSITE | PS00018 | EF_HAND_1 | coord: 383..395 |
| IPR011992 | EF-hand domain pair | SUPERFAMILY | 47473 | EF-hand | coord: 252..399 |
| IPR011992 | EF-hand domain pair | SUPERFAMILY | 47473 | EF-hand | coord: 45..197 |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | SUPERFAMILY | 52540 | P-loop containing nucleoside triphosphate hydrolases | coord: 884..1062 |
Blast
BLAST of TCONS_00011884-protein vs. Swiss-Prot (Human)
Match: RASEF (Ras and EF-hand domain-containing protein OS=Homo sapiens GN=RASEF PE=1 SV=1) HSP 1 Score: 206.068 bits (523), Expect = 2.077e-55 Identity = 172/614 (28.01%), Postives = 293/614 (47.72%), Query Frame = 0
Query: 521 DPNTTKVFESFLGKVYNELRTARQETKHLENVLERKSQVHQEEMKKIYDEVEIQMQTEKLKQTQQLAEKETVLREDMLRELKEKEGQIEKMIQRENTLANRLSNVKEQE--QSLKHQNSKLMKENMQLEDQLNDSMSNLSYLKTNLQHMEEQTTAEKKETLKAAVQATQGIQSEHESLIKQLDLLRSMNQKLRDERDSLELSIRSKTSRLDDIDGIEDSIPAKKPISRHGSNI--GKYIQERSSSTPTHSPLSKQGSIMSNYFEPLGDHRHSSFS---ENLDA-----QLSRIGEGEVDT---SVFDSVIE-MDEPSSNEALIIDTHQQSVNN----EPDLGSQTSSSPAPSSPRQEPVGMNN-------DEEHFSDNISSVSHSTAPVETPS----------------RVYKCVFVGDSGVGKSSFIHRFCFDEFQKNFSATIGVDMHVKTIKVKRQWVALQLWDTAGQERFRSITKNYFRRADGVIVMFDVTSETSFLNVKGWMLNIEEGAEPDCQIMLLGNKKDLCDNHPKK-RKITP-EMAQTLADSFGATYYEVSALSGTGVLESIDHLATRMALNEDGLMQKSVIDIHKYCNAEGANGEK----KKCC 1085
+P + +E + E+R E ++L ++R ++ ++ +E++ ++Q + K + K D+ R+ + + G ++ I++ L + V ++E +LK Q L EN +++ L ++ +N+++L++ L ++ A++ + ++ + + SL +Q+++L++ N+KL D D L ++ + S+ + S H +NI G I S HSP +PLG R S S E+ D+ L R EVD+ S FDS + + +P+ ++ + HQ+ + G S + P +E G+ + + S VS S P+ S + YK V GD+ VGKSSF+ R C +EF++N SAT+GVD +KT+ V + LQLWDTAGQERFRSI K+YFR+ADGV++++DVT E SFLN++ W+ IE+ A IML+GNK D+ D + +K P + LA ++GA + E SA G+ ++E++ HLA + D +S+ N G N +K K CC
Sbjct: 159 EPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDY-ADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSALENSYSKFNR--------------SLHINNISPGNTISRSSPKFIGHSP------------QPLGYDRSSRSSYVDEDCDSLALCDPLQRTN-CEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT------NLTGTNSKKSPQMKNCC 738
The following BLAST results are available for this feature:
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