TCONS_00012430-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012430-protein
Unique NameTCONS_00012430-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length461

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012430-protein ID=TCONS_00012430-protein|Name=TCONS_00012430-protein|organism=Clytia hemisphaerica|type=polypeptide|length=461bp
MEHPSVTLKNLAKENNIYDITSKDLATLLDKQDELSKYRKQFAYPRMKTL
PKVDLSIVNGEEDCVYLCGHSLGLCPKKTEDVMMEEIKKWKEMGVEGHMN
GKYPWAFIEEYIFKQMARLVGCKEIEVWIMNTLSVNLNVMMVPFYRPNPN
RHKILIETGAFPSDHIAVEAQIRYHGYDPATSLLIAKPRTGEESIKMDDL
IELIEKEGDEIALILFAGVQYYTGQFFDLKRITDAGHKKGCIVGFDLAHA
VGNVELKLHDWNVDFACWCTYKYMNSGPGATGGVYLHEKYANENYNLKRH
AGWWGVDFENRFKMDNSDLPFVPGPAGFAHSNPPLFSTMGLFASLEQFDD
VGIQKLVKKQRLLTGYLELLINTHFNKPNEKQHVSYITPLSIEERGCMLS
FAFSFPIENIFAGLVKRGVVCDVRKPKVLRIAPAPFYNSFDDVHRFVQIL
LDVIEQNKNEN
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006979XLOC_006979Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012430TCONS_00012430Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000192Aminotrans_V_dom
IPR015422PyrdxlP-dep_Trfase_sub2
IPR010111Kynureninase
IPR015421PyrdxlP-dep_Trfase_major_sub1
IPR015424PyrdxlP-dep_Trfase
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0030429kynureninase activity
GO:0030170pyridoxal phosphate binding
Vocabulary: Biological Process
TermDefinition
GO:0006569tryptophan catabolic process
GO:0009435NAD biosynthetic process
Vocabulary: Cellular Component
TermDefinition
GO:0005737cytoplasm
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0009435 NAD biosynthetic process
biological_process GO:0006569 tryptophan catabolic process
cellular_component GO:0005737 cytoplasm
molecular_function GO:0003824 catalytic activity
molecular_function GO:0030429 kynureninase activity
molecular_function GO:0030170 pyridoxal phosphate binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000192Aminotransferase class V domainPFAMPF00266Aminotran_5coord: 191..371
e-value: 1.6E-10
score: 40.4
IPR015422Pyridoxal phosphate-dependent transferase, subdomain 2GENE3D3.90.1150.10coord: 343..461
e-value: 1.2E-18
score: 66.6
IPR010111KynureninaseTIGRFAMTIGR01814TIGR01814coord: 28..454
e-value: 1.3E-127
score: 424.0
IPR010111KynureninasePIRSFPIRSF038800KYNUcoord: 19..461
e-value: 3.8E-147
score: 488.2
IPR010111KynureninaseHAMAPMF_01970Kynureninasecoord: 5..454
score: 43.109
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1GENE3D3.40.640.10coord: 76..342
e-value: 5.6E-29
score: 100.6
IPR015424Pyridoxal phosphate-dependent transferaseSUPERFAMILY53383PLP-dependent transferasescoord: 24..456

Blast
BLAST of TCONS_00012430-protein vs. Swiss-Prot (Human)
Match: KYNU (Kynureninase OS=Homo sapiens GN=KYNU PE=1 SV=1)

HSP 1 Score: 438.343 bits (1126), Expect = 2.354e-151
Identity = 220/465 (47.31%), Postives = 312/465 (67.10%), Query Frame = 0
Query:    1 MEHPSVTLKNLAKENNIYDITSKDLATLLDKQDELSKYRKQFAYPRMKTLPKVDLSIVNGEEDCVYLCGHSLGLCPKKTEDVMMEEIKKWKEMGVEGHMNGKYPWAFIEEYIFKQMARLVGCKEIEVWIMNTLSVNLNVMMVPFYRPNPNRHKILIETGAFPSDHIAVEAQIRYHGYDPATSLLIAKPRTGEESIKMDDLIELIEKEGDEIALILFAGVQYYTGQFFDLKRITDAGHKKGCIVGFDLAHAVGNVELKLHDWNVDFACWCTYKYMNSGPGATGGVYLHEKYANENYNLKRH-AGWWGVDFENRFKMDNSDLPFVPGPAGFAHSNPPLFSTMGLFASLEQFDDVGIQKLVKKQRLLTGYLELLINTHFNK---PNEKQHVSYITPLSIEERGCMLSFAFSFPIENIFAGLVKRGVVCDVRKPKVLRIAPAPFYNSFDDVHRFVQILLDVIEQNKNEN 461
            +E P+ T++ +A E   +  T + +A  LD++D+L  +R+ F  P+++ LP VDLS+VN +E+ +Y  G+SLGL PK  +  + EE+ KW ++   GH  GK PW   +E I   M  +VG  E E+ +MN L+VNL+++M+ F++P P R+KIL+E  AFPSDH A+E+Q++ HG +   S+ + KPR GEE+++++D++E+IEKEGD IA+ILF+GV +YTGQ F++  IT AG  KGC VGFDLAHAVGNVEL LHDW VDFACWC+YKY+N+G G   G ++HEK+A   + +K    GW+G +   RFKMDN  L  +PG  GF  SNPP+     L ASLE F    ++ L KK  LLTGYLE LI  ++ K     +K  V+ ITP  +EERGC L+  FS P +++F  L KRGVVCD R P  +R+AP P YNSF DV++F  +L  +++  + +N
Sbjct:    6 LELPADTVQRIAAELKCHP-TDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHA---HTIKPALVGWFGHELSTRFKMDNK-LQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465          
The following BLAST results are available for this feature:
BLAST of TCONS_00012430-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
KYNU2.354e-15147.31Kynureninase OS=Homo sapiens GN=KYNU PE=1 SV=1[more]
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