TCONS_00012956-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012956-protein
Unique NameTCONS_00012956-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length576

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012956-protein ID=TCONS_00012956-protein|Name=TCONS_00012956-protein|organism=Clytia hemisphaerica|type=polypeptide|length=576bp
MDGASILAKSLADQGVEYMFGIVGIPVMEVAIAAQQIGIKYIGMRNEQSA
SYAASAVGYLTGRPAVCLVVSGPGLIHALAGMANAKENCWPMMVVGGSSD
TNQEQMGAFQEIPQVEAARQYCKLSARPNAVEDIPFYVEKAVRHSIQGRP
GVVYLDLPGDLIRAVSQDEERIRWTLRSPEPLISVCPPSQIHIALDTLMS
AKRPLLVIGKGAAYGRSEDSLRRFIDQTGLPFLPTPMGKGVVSDNHPQCV
SAARSKALLRADVIFLVCARLNWILHFGLPPRFHQNVQFIQLDIAPEEIG
NNAPSTVGLFGNVNAIVNQMCQGFEEKFSGKKFERSQPWWKELESKVEDN
KQKTQMMIESSGIPMNFYHMYDEICKDLPGGCIIVNEGANTMDIGRTMIT
HNLPRKRLDAGSFGTMGVGSGFAIAAALVEMNQALKEDRPPCRVVCVQGD
SAFGFGGMELETAARYHLPIIFIIANNNGIYNGLDRESYDTVTTEAEQTS
LPLVLPPVSLNPNICYEKIMHAFGCRGVEVIQPSELHLSLKEALADTERP
SLLHVRIESTSGRKQQEFDWLTKSKL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007275XLOC_007275Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012956TCONS_00012956Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR029035DHS-like_NAD/FAD-binding_dom
IPR012001Thiamin_PyroP_enz_TPP-bd_dom
IPR011766TPP_enzyme-bd_C
IPR012000Thiamin_PyroP_enz_cen_dom
IPR029061THDP-binding
Vocabulary: Molecular Function
TermDefinition
GO:0030976thiamine pyrophosphate binding
GO:0003824catalytic activity
GO:0000287magnesium ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0003824 catalytic activity
molecular_function GO:0000287 magnesium ion binding
molecular_function GO:0030976 thiamine pyrophosphate binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR029035DHS-like NAD/FAD-binding domainGENE3D3.40.50.1220coord: 184..340
e-value: 1.9E-30
score: 105.2
IPR029035DHS-like NAD/FAD-binding domainSUPERFAMILY52467DHS-like NAD/FAD-binding domaincoord: 187..351
IPR012001Thiamine pyrophosphate enzyme, N-terminal TPP-binding domainPFAMPF02776TPP_enzyme_Ncoord: 1..164
e-value: 1.2E-44
score: 151.8
IPR011766Thiamine pyrophosphate enzyme, C-terminal TPP-bindingPFAMPF02775TPP_enzyme_Ccoord: 390..555
e-value: 8.5E-24
score: 84.0
NoneNo IPR availableGENE3D3.40.50.970coord: 1..183
e-value: 6.3E-46
score: 155.7
NoneNo IPR availableGENE3D3.40.50.970coord: 341..568
e-value: 1.3E-35
score: 122.4
NoneNo IPR availableCDDcd07035TPP_PYR_POX_likecoord: 6..158
e-value: 1.02483E-55
score: 185.428
NoneNo IPR availableCDDcd02004TPP_BZL_OCoD_HPCLcoord: 367..558
e-value: 5.66825E-63
score: 205.459
IPR012000Thiamine pyrophosphate enzyme, central domainPFAMPF00205TPP_enzyme_Mcoord: 194..319
e-value: 2.6E-29
score: 101.6
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 1..174
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 364..559

Blast
[Close]
BLAST of TCONS_00012956-protein vs. Swiss-Prot (Human)
Match: HACL1 (2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens GN=HACL1 PE=1 SV=2)

HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0
Identity = 313/577 (54.25%), Postives = 417/577 (72.27%), Query Frame = 0 
Query:    1 MDGASILAKSLADQGVEYMFGIVGIPVMEVAIAAQQIGIKYIGMRNEQSASYAASAVGYLTGRPAVCLVVSGPGLIHALAGMANAKENCWPMMVVGGSSDTNQEQMGAFQEIPQVEAARQYCKLSARPNAVEDIPFYVEKAVRHSIQGRPGVVYLDLPGDLIRAVSQDEERIRWTLRSPEPLISVCPPSQIHIALDTLMSAKRPLLVIGKGAAYGRSEDSLRRFIDQTGLPFLPTPMGKGVVSDNHPQCVSAARSKALLRADVIFLVCARLNWILHFGLPPRFHQNVQFIQLDIAPEEIGNNAPSTVGLFGNVNAIVNQMCQGFEEKFSGKKFERSQPWWKELESKVEDNKQKTQMMIESSGIPMNFYHMYDEICKDLPGGCIIVNEGANTMDIGRTMITHNLPRKRLDAGSFGTMGVGSGFAIAAALVEMNQALKEDRPPCR-VVCVQGDSAFGFGGMELETAARYHLPIIFIIANNNGIYNGLDRESYDTVTTEAEQTSLPLVLPPVSLNPNICYEKIMHAFGCRGVEVIQPSELHLSLKEALADTERPSLLHVRIESTSGRKQQEFDWLTKSKL 576
            + GA ++A++L  Q VEY+FGIVGIPV E+AIAAQQ+GIKYIGMRNEQ+A YAASA+GYLT RP VCLVVSGPGLIHAL GMANA  NCWP++V+GGSS+ NQE MGAFQE PQVEA R Y K SARP+++E IPF +EKAVR SI GRPG  Y+D+P D +  +  +   I++  R   P IS+   S +  A   + +AK+PLL+IGKGAAY  +E+S+++ ++Q  LPFLPTPMGKGVV DNHP CV AARS+AL  ADVI L  ARLNWILHFGLPPR+  +V+FIQ+DI  EE+GNN    V L GN++A+  Q+ +  ++  +  ++     WWK L  K++ N+  ++ +     +PMN+Y ++  + + LP  C +V+EGANTMDIGRT++ + LPR RLDAG+FGTMGVG GFAIAAA+V       +DR P + ++CV+GDSAFGF GME+ET  RY+LPII ++ NNNGIY G D +++  +    + T+   V+PP+ L PN  YE++M AFG +G  V  P EL  SL+++LADT +PSL+++ IE  + RK Q+F WLT+S +
Sbjct:   14 VSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN-LQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVV------AKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATA---VVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM 578
The following BLAST results are available for this feature:
BLAST of TCONS_00012956-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HACL10.000e+054.252-hydroxyacyl-CoA lyase 1 OS=Homo sapiens GN=HACL1... [more]
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