TCONS_00016035-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00016035-protein
Unique NameTCONS_00016035-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1574

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00016035-protein ID=TCONS_00016035-protein|Name=TCONS_00016035-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1574bp
MAQFLWQVAVMVTVLQLFTPVVGKPSFAQTGYELVYPERIHKHRSKRDLS
TKQKEGNHDEFVSYRIPSIDKYIVLDLKKRKSHLTSGNVKIITHDEKGAQ
QVEELSPEDCHYVGQIRDVEDSHAFISTCHGLTGTLDDGENRYDIVPYDD
EGQHRFTRVNDHLDEIYKSLQMSSFTESRVDDAPKIRKRRSTFNGNVPGL
RTFDLINVEPQYIPYLKTNKTRYVELLVSVGKGVTETYGNNYSLILERML
NALGQVDLSYQAINIRLVLTALEIQTKDRFQRSSNGGGELSNYATYVINT
IKKLDFYKDISFDHGMFMSKTGWNDGVVGMAYVGGVCSSSIQYSVNLWSA
NAISGPTVILGHELGHNLNFPHDSDQCKCLTPRGCFMGGSKSSRPGFSNC
SLSRLAQKEFACIDNAPKATMLRRCGNGIKDPGEECDCGTEENCKKSNDH
CCEPKSCKLKAHVQCSHFNYPGCCSETCYYRKEGTLCRNADGNCDVEEYC
TGDSPACPANRYMRNGIKCEESIKMLFGTKSRYGETINQLSHQVIGRYFK
IETKKWGAGNWACLRMEMYGCHANRANVPTPISTVDLYYHKRMCVTPKID
TDAECANIPDGTNLIYKEMPNFDCDHKRMLFDYNADGSLIHHCSGKRICL
DQNGFLQVSSQCGIEESKFERTEALSVKQNGKCWLAERKWPFPNKRITLS
DMCEDKTNSITVHQFYETDCKMPQGFMNGKLPDSAFSASSFAVGDEPFKA
RIGNAGKWCPHKAGIGGWLKIDLGKQVKITAIGISSGSYWNWVTGYHLYS
SDDGKHWTPFKDLSDQNSNVNNSMCFNGVCQKTLNHQCQSLWNVDTKSAP
NECWDKLNTEAKGFGTCSPTANTSCTTENVKCGQIQCQSPDDRPYYIDYG
TQYKKIDSSSHTCSAASITDSEQVGLGMVQDGTKCGENKFCMNQQCKTAK
DHGIKECFIVDGKECNGKGVCRNGGVCQCEGLLNPLTGCKTVYSPIDGGF
SQWNEWTTCTKGCGGGTQSRYRHCDQPTPKHGGKSCGGDLLESRNCNTDA
CPLGRSCLAIQLILQKEERPLYDGIYQIKPIESQHSFPVYCDMTSDGGGW
TLLVSSHMNNWTEANVVLRNPQTPSLSHDYSILKRGDAIKRNYLISEPNF
EYKIEAHTRGHWGGIWRAPNSYSISSSNSYQTDVTLLKKFNDWQYQSRGL
QERLPYLNKQRLTTSFGEWGSITDNEHAVLPANYISGDHMMAMPEHVWYW
MREGKYAYPESCLQIMHRGFQEKQTFKSGLYKIKVKEEIVQTYCDFDRHG
GGWTLVTKVSSSNGWTKENSILRNKDDASKDDFSIFKYIDELKFKDPAEA
TFDYMVEADGTDTNGGIFSLSADFTLLNCAPKDKKPILRKKFGNWDEGVE
NFAKNPITAGSKNGIFLSASRSDDSSDVLGTIVSSGNGKYLSTLVKPNVV
KVWVREGGSRSSCNDIKIRGYHKEKTDYKDGFYMLKDNLNVYCDMETTPK
EGWTLLVSSNNNGWSGDQVLERNINHPGLHIDYSILGRANQMKSLSKNNT
FKYMLDAKRRGHWGGIWSAPIGYS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_008961XLOC_008961Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00016035TCONS_00016035Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001762Disintegrin_dom
IPR000884TSP1_rpt
IPR006586ADAM_Cys-rich
IPR008979Galactose-bd-like
IPR001590Peptidase_M12B
IPR002181Fibrinogen_a/b/g_C_dom
IPR014716Fibrinogen_a/b/g_C_1
IPR000421FA58C
IPR024079MetalloPept_cat_dom
IPR002870Peptidase_M12B_N
IPR034027Reprolysin_adamalysin
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001762Disintegrin domainSMARTSM00050DISIN_2coord: 431..513
e-value: 7.8E-28
score: 108.5
IPR001762Disintegrin domainGENE3D4.10.70.10coord: 436..509
e-value: 6.2E-18
score: 64.8
IPR001762Disintegrin domainPFAMPF00200Disintegrincoord: 431..509
e-value: 1.3E-17
score: 64.2
IPR001762Disintegrin domainPROSITEPS50214DISINTEGRIN_2coord: 422..515
score: 16.288
IPR001762Disintegrin domainSUPERFAMILY57552Blood coagulation inhibitor (disintegrin)coord: 431..513
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 1000..1052
e-value: 2.5E-14
score: 63.6
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 1001..1051
e-value: 9.8E-10
score: 38.4
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 996..1051
e-value: 1.0E-15
score: 57.2
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 997..1052
score: 13.557
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 995..1051
IPR006586ADAM, cysteine-richSMARTSM00608acrcoord: 816..949
e-value: 4.6E-23
score: 92.6
IPR006586ADAM, cysteine-richPFAMPF08516ADAM_CRcoord: 821..919
e-value: 1.8E-16
score: 60.5
IPR008979Galactose-binding domain-likeGENE3D2.60.120.260coord: 717..837
e-value: 7.8E-22
score: 77.3
IPR008979Galactose-binding domain-likeGENE3D2.60.120.260coord: 510..583
e-value: 0.012
score: 15.0
IPR008979Galactose-binding domain-likeSUPERFAMILY49785Galactose-binding domain-likecoord: 717..822
IPR008979Galactose-binding domain-likeSUPERFAMILY49785Galactose-binding domain-likecoord: 521..572
IPR001590Peptidase M12B, ADAM/reprolysinPFAMPF01421Reprolysincoord: 222..417
e-value: 1.4E-26
score: 93.5
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 222..407
score: 26.036
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainPFAMPF00147Fibrinogen_Ccoord: 1074..1104
e-value: 1.8E-5
score: 24.5
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainPROSITEPS51406FIBRINOGEN_C_2coord: 1253..1306
score: 11.699
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainPROSITEPS51406FIBRINOGEN_C_2coord: 1048..1107
score: 11.706
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainSUPERFAMILY56496Fibrinogen C-terminal domain-likecoord: 1256..1311
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainSUPERFAMILY56496Fibrinogen C-terminal domain-likecoord: 1053..1110
IPR014716Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1GENE3D3.90.215.10coord: 1456..1533
e-value: 0.0011
score: 18.4
coord: 1052..1197
e-value: 4.2E-9
score: 35.9
IPR014716Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1GENE3D3.90.215.10coord: 1255..1343
e-value: 1.2E-8
score: 34.5
IPR000421Coagulation factor 5/8 C-terminal domainPFAMPF00754F5_F8_type_Ccoord: 737..820
e-value: 1.6E-10
score: 41.1
IPR000421Coagulation factor 5/8 C-terminal domainPROSITEPS50022FA58C_3coord: 720..812
score: 18.66
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 217..435
e-value: 4.8E-34
score: 117.5
IPR002870Peptidase M12B, propeptidePFAMPF01562Pep_M12B_propepcoord: 36..152
e-value: 6.5E-19
score: 68.5
IPR034027Reprolysin domain, adamalysin-typeCDDcd04269ZnMc_adamalysin_II_likecoord: 222..415
e-value: 1.93881E-32
score: 125.806
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 221..417

Blast
[Close]
BLAST of TCONS_00016035-protein vs. Swiss-Prot (Human)
Match: ADAM8 (Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens GN=ADAM8 PE=1 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 7.041e-52
Identity = 165/533 (30.96%), Postives = 240/533 (45.03%), Query Frame = 0 
Query:    5 LWQVAVMVTVLQLFTPVVGKPSFAQTGYELVYPERIHKHRSKRDLSTKQKEGNHDEFVSYRIPSIDKYIVLDLKKRKSHLTSGNVKIITHDEKGAQQVEELSPED-CHYVGQIRDVEDSHAFISTCHGLTGTLDDGENRYDIVPYDD--EGQHRFTRVNDHLDEIYKSLQMSSFTESRVDDAPKIRKRRSTFNGNVPGLRTFDLINVEPQYIPYLKTNKTRYVELLVSVGKGVTETYGNNYSLILERMLNALGQVDLSYQAINIRLVLTALEI-QTKDRFQRSSNGGGELSNYATYVINTIKKLDFYKDISFDHGMFMSKTGWNDGVVGMAYVGGVCSSSIQYSVNLWSANAISGPTVILGHELGHNLNFPHDSD--QCKC---LTPRGCFMGGS-KSSRPG-FSNCSL----SRLAQKEFACIDNAPKATML---RRCGNGIKDPGEECDCGTEENCKKSNDHCCEPKSCKLKAHVQCSHFNYPGCCSETCYYRKEGTLCRNADGNCDVEEYCTGDSPACPANRYMRNGIKC 519
            LW +  M+  L    P   +P      YE+V P R+   R +R L +    G H E VSY + +      L L+K +  L SG  +  T    G++  E+   +D C Y G +    DS A +STC GL G    G + + I P D+  EG        +HL +   +  +S       DD+           G++ G RT  +    P     L + +TRYVEL V V     +  G+  + +  R+L  +  VD  YQ +N R+VL  LEI  ++DRF  S +    L N  T+      +   + ++    G+  + T      VG A V  +CS S   +VN   +    G    + HE+GHNL   HD +   C+C        C M GS  SS P  FS+CS     S L + +  C+ NAP  + L     CGN   + GE+CDCG  E+C+   + CC   +C+L    QC+H    G C + C  +  G LCR     CD+EE+C G  P CP + +  NG  C
Sbjct:    6 LWLLGAMM--LPAIAP--SRPWALMEQYEVVLPWRLPGPRVRRALPSHL--GLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYT-AANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVS-------DDS----------LGSLLGPRTAAVFRPRPGD--SLPSRETRYVELYVVVDNAEFQMLGSE-AAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGT-----TVGFARVSAMCSHS-SGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCR---NRCCNSTTCQLAEGAQCAH----GTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPC 498
The following BLAST results are available for this feature:
BLAST of TCONS_00016035-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ADAM87.041e-5230.96Disintegrin and metalloproteinase domain-containin... [more]
back to top