TCONS_00019469-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00019469-protein
Unique NameTCONS_00019469-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1127

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00019469-protein ID=TCONS_00019469-protein|Name=TCONS_00019469-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1127bp
MNIYQRLFSRTSIQFFVLLLSCELICRCTHAKLYARSLNNANNLYSGNNK
NNNNNNSTVLNRTIVTLGVFVPWTGSWPVGKKLASAATVAIDDINNDTTL
MKNEHLQFIWKDDKCDGEQTVGKTAELYYTYENQGRKGVDAYIGPYCSEG
CVSGGLLAAFLEKPMISYSCSKDTLSNKTIYPTFARTKTFVRSYPKILSR
KLVALMKKHGWSLITLVVSTESGWHTFAQGVFTELMQHNIQVADKLTYNK
NKNDYEHVLNLAKDKARIFALLGYHPETAKLLVKAREMGMFNGENVFITM
DFEVESNWEKQDWLGGYTVDEAFNGFLDMSVESPESLGDGTYKKFQERVR
EKMAEDPFDYQMKPDEKVHIDAAFLYDAIYLYALAYNKTKAAGGDPYNAT
QLMKNVFSANFRGKTGQVVLKKGDRTPILEVRNFQSGKPVHICTFGLQEN
DECTNSKGKVDIVWPGGVKTAPLDRPKCGFNGELCKQDEDQENTLIQILA
IIFGILFILIGLIVVFVYKRRKYEKDLLGKGFIVNYDEIVNQGTYGGGGG
GHAQQNGKVMGGSISSKSPSFRHKYRSMSRLPDTYSVQSDTESMMERSQF
IVSYRGQHVMIKKLNKTTSNVNRENLLEFKQIREIHHVNVCQVVGVCVQC
PNVCILTQYCSKGSLQDVLQNSDIRLDWMFKMSFATDIASGAYELHRNGI
IHGRLHSNNCVIDNRWVCKITDYGMDKFKQTHHNNNQEDETEYQKYRKLL
WQAPELLKSTSSDDKDGKTKEGDIYSFGIILSEILTREDPYYDYEMEPKD
IIKNVRARHEPPFRPKVNEADCEDNRYCALMKSCWTDCPSQRPNFENVKG
RLKRMSGGRTGNLMDNMIEMMGRYTDNLEDLVEERTQQLAAEKAKTDELL
YKMLPKTIAEQLKMGEQVTAETFESVTIFFSDIVGFTSLAGASTPMQVVD
LLNDLYTCFDKCIDNYDVYKVETIGDAYMVVSGLPQRNGFKHAGEIATMS
LDLLHHTKTFRIRHLPEKFLQLRIGIHSGSCVAGVVGLKMPRYCLFGDTV
NYASRMESSGLALRVHISPECKELLDQLGGYQLIDRGPTNMKGKGTINTY
FLGGKQGFDKSLPDLTNAAGLDQHVFK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010942XLOC_010942Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00019469TCONS_00019469Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001170ANPR/GUC
IPR001054A/G_cyclase
IPR011645HNOB_dom_associated
IPR001828ANF_lig-bd_rcpt
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR018297A/G_cyclase_CS
IPR000719Prot_kinase_dom
IPR028082Peripla_BP_I
IPR011009Kinase-like_dom
IPR029787Nucleotide_cyclase
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0009190cyclic nucleotide biosynthetic process
GO:0035556intracellular signal transduction
GO:0006182cGMP biosynthetic process
GO:0006468protein phosphorylation
Vocabulary: Molecular Function
TermDefinition
GO:0016849phosphorus-oxygen lyase activity
GO:0004383guanylate cyclase activity
GO:0004672protein kinase activity
GO:0005524ATP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006182 cGMP biosynthetic process
biological_process GO:0009190 cyclic nucleotide biosynthetic process
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0006468 protein phosphorylation
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005524 ATP binding
molecular_function GO:0004383 guanylate cyclase activity
molecular_function GO:0016849 phosphorus-oxygen lyase activity
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 864..884
NoneNo IPR availableGENE3D3.40.50.2300coord: 62..416
e-value: 2.4E-46
score: 157.9
NoneNo IPR availableGENE3D1.10.510.10coord: 649..919
e-value: 3.3E-43
score: 147.4
NoneNo IPR availableGENE3D3.30.200.20coord: 417..648
e-value: 7.4E-8
score: 32.0
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..22
score: 5.0
NoneNo IPR availableCDDcd07302CHDcoord: 926..1102
e-value: 1.5993E-62
score: 210.128
NoneNo IPR availableCDDcd06352PBP1_NPR_GC_likecoord: 66..425
e-value: 1.60137E-66
score: 228.735
IPR001170Adenylyl cyclase class-4/guanylyl cyclasePRINTSPR00255NATPEPTIDERcoord: 498..520
score: 22.83
coord: 375..393
score: 44.41
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseSMARTSM00044cyc_6coord: 891..1085
e-value: 3.2E-99
score: 345.6
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseGENE3D3.30.70.1230coord: 920..1108
e-value: 1.0E-74
score: 249.8
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePFAMPF00211Guanylate_cyccoord: 919..1102
e-value: 2.9E-64
score: 215.9
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePROSITEPS50125GUANYLATE_CYCLASE_2coord: 927..1057
score: 50.834
IPR011645Haem NO binding associatedPFAMPF07701HNOBAcoord: 879..912
e-value: 5.7E-6
score: 25.8
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 84..436
e-value: 3.1E-51
score: 174.4
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 606..850
e-value: 5.7E-42
score: 143.7
IPR018297Adenylyl cyclase class-4/guanylyl cyclase, conserved sitePROSITEPS00452GUANYLATE_CYCLASE_1coord: 1034..1057
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 539..855
score: 24.796
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 65..480
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 605..891
IPR029787Nucleotide cyclaseSUPERFAMILY55073Nucleotide cyclasecoord: 913..1102

Blast
[Close]
BLAST of TCONS_00019469-protein vs. Swiss-Prot (Human)
Match: ANPRB (Atrial natriuretic peptide receptor 2 OS=Homo sapiens GN=NPR2 PE=1 SV=1)

HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0
Identity = 374/995 (37.59%), Postives = 535/995 (53.77%), Query Frame = 0 
Query:  140 DAYIGPYCSEGCVSGGLLAAFLEKPMISYSCSKDTLSNKT-IYPTFARTKTFVRSYPKILSRKLVALMKKHGW----SLITLVVSTESGWHTFA-QGVFTELMQHNIQVADKLTYNKNKNDYEHVLNLAKDKARIFALLGYHPETAKLLVKAREMGMFNGENVFITMDFEVES------NWEKQDWLGGYT------VDEAFNGFLDMSVESPESLGDGTYKKFQERVREKMAEDPFDYQMKPDEKVHIDAAFLYDAIYLYALAYNKTKAAGGDPYNATQLMKNVFSANFRGKTGQVVL-KKGDRTP---ILEVRNFQSGKPVHICTFGLQENDECTNSKGKVDIVWPGGVKTAPLDRPKCGFNGELCKQDEDQENTLIQILAIIFGILFILIGLIVVFVYKRRKYEKDLLGKGFIVNYDEIV--NQGTYGGGGGGHAQQNGKVMGGSISSKSPSFRHKYRSMSRLPDTYSVQSDTESMMERSQFIVSYRGQHVMIKKLNKTTSNVNRENLLEFKQIREIHHVNVCQVVGVCVQCPNVCILTQYCSKGSLQDVLQNSDIRLDWMFKMSFATDIASGAYELHRNGII--HGRLHSNNCVIDNRWVCKITDYGMDKFKQTHHNNNQEDETEYQKYRKLLWQAPELLKSTSSDDKDGKTKEGDIYSFGIILSEILTREDPYY--DYEMEPKDIIKNVRARHEPPFRPKVNEADCEDNRYCALMKSCWTDCPSQRPNFENVKGRLKRMSGGRTGNLMDNMIEMMGRYTDNLEDLVEERTQQLAAEKAKTDELLYKMLPKTIAEQLKMGEQVTAETFESVTIFFSDIVGFTSLAGASTPMQVVDLLNDLYTCFDKCIDNYDVYKVETIGDAYMVVSGLPQRNGFKHAGEIATMSLDLLHHTKTFRIRHLPEKFLQLRIGIHSGSCVAGVVGLKMPRYCLFGDTVNYASRMESSGLALRVHISPECKELLDQLGGYQLIDRGPTNMKGKGTINTYFLGGKQ 1106
            D  +GP C     S    A+    P+++        S K   Y T  RT     S PK L   +V L     W    +L+ L   T+   H F  +GVF  L   N+ V  ++ Y +     E   +  +   RI  + G      ++L++A+   + NG+ VF  +D   ES          + W    T      + EAF   L ++   P    +  Y++FQ R+  +  ED F  ++ P   +++ A   YD I LYA   N+T   GG   +  ++++ +    + G TG VV+ K  DR     +  + +  SG       +   E       +    I W  G    P D P C F+ +    D+   +TL  I+A+  GI FI+ G+    ++++   EK+L    + + ++E+   N   Y  G G            ++S +  S    Y S+      Y + ++T            ++G  V IK +NK    + R+ L E K +R++   ++ + +G C+  PN+CI+T+YC +GSLQD+L+N  I LDWMF+ S   D+  G   LH N II  HG L S+NCV+D+R+V KITDYG+  F+ T      E +  +  Y K LW APELL            ++ D+YSFGIIL EI  R  P+Y    ++ PK+I++ VR    P FRP ++     +     LM+ CW   P++RP+F  +KG ++R +     +++DN++  M +Y +NLE LVEERTQ    EK K + LLY++LP ++AEQLK GE V AE F+SVTI+FSDIVGFT+L+  STPMQVV LLNDLYTCFD  IDN+DVYKVETIGDAYMVVSGLP RNG +HA EIA M+L LL    +FRIRH P   L+LRIG+H+G   AGVVGLKMPRYCLFGDTVN ASRMES+G AL++H+S   K+ LD+LG +QL  RG   MKGKG + TY+L G++
Sbjct:   94 DLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGP---SAPK-LGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQV-YAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYREPP---NPEYQEFQNRLLIRARED-FGVELGPS-LMNLIAGCFYDGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGR---PIPWVKG--APPSDNPPCAFDLDDPSCDKTPLSTL-AIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRL---------TLSLRGSS----YGSLMTAHGKYQIFANTGH----------FKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLH-NSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRST-----AEPDDSHALYAKKLWTAPELLSGNPLPTTG--MQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEE-LVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGER 1040
The following BLAST results are available for this feature:
BLAST of TCONS_00019469-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ANPRB0.000e+037.59Atrial natriuretic peptide receptor 2 OS=Homo sapi... [more]
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