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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00026429-protein ID=TCONS_00026429-protein|Name=TCONS_00026429-protein|organism=Clytia hemisphaerica|type=polypeptide|length=932bp
RMGCRSIELDLWDGQTDPIIYHGLTLTSKIKLVDVVQVIASNAFEVTPYP
LILSLENHCTIPQQIKMANMFKKYFGKSLVTQYLDANEKQLPSPESLKYK
VILKYKKIDQGQSDVFLSSLNSRDSAIWDDTLLSSSLKTGLVYMEDEEKK
WNKHLFVLTQTSIHYSFEQETTTQDDEDEDEIVETQEQNKDGNEDELHFS
EKWFHRNISRVEAEKLLREYQKGDGSFLVRPSNMFVGDFSLSFWRQNKVQ
HCRIKLRQTQDGSTKYFLVGQKSFDNLWSLINHYQLNPLRSDQFEMTLNE
PIPQPNAHIGKPWYHDNLTRQQAEDMLKRMRKDGYFLVRKRMGSNELDPD
SDSYAISFRTAGSIKHCVIKKEGRLFMIGSAPFESLVELISHYEKFALYR
QTKLKFPCNQEVVKELGINPDLEEEAPDSFYALPNATTHKPACLAKYDYI
GKDDELKFPKGAMITNVVKFDGGWWRGDYNGQVQKWFPVNFTEETVIKEK
APVSQQEIESKQGGVMLEEMQKGVIDLTGCQQQLLQSQPSRPYIFSIKSQ
SGVFNCSVESEHEMIEWVTAIQDASTKAQESSSQLKQLVEQRKIAKELSD
LIVYCVTVPFNEEGFENGKYYQMSSFPELKAERFVSRKTVDLRFLRLNHR
QLSRVYPKGTRFDSSNYDPVIFWNFGCQMVALNYQTPDRSMQIERGTFLD
NGGCGYVLQPDILRDPNFNPYDPTTFNKLVEPLNLRLTIIGARHLPKTGR
GLTSPFVEVEIVGLSYDCRSFQTKTKQDNGLCPTWFERLEFDVICPPLAK
IRFVVHDEDMFGDPNFVAQACFPVTTLRPGHRSIPLKNAYSEEIPLAALL
IELEIKNAQEDEEYASIAELRDKMQRLMETQDSTQRMEENEAQSQLMQFQ
DQLSRLTLDREARHQEADNIKKQKVSHKSSSG Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0035556 | intracellular signal transduction |
| GO:0007165 | signal transduction |
| GO:0006629 | lipid metabolic process |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005515 | protein binding |
| GO:0004435 | phosphatidylinositol phospholipase C activity |
| GO:0008081 | phosphoric diester hydrolase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0006629 |
lipid metabolic process |
| biological_process |
GO:0007165 |
signal transduction |
| molecular_function |
GO:0004435 |
phosphatidylinositol phospholipase C activity |
| molecular_function |
GO:0008081 |
phosphoric diester hydrolase activity |
| molecular_function |
GO:0005515 |
protein binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 867..887 |
| None | No IPR available | COILS | Coil | Coil | coord: 571..598 |
| None | No IPR available | COILS | Coil | Coil | coord: 889..909 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 169..195 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 903..932 |
| None | No IPR available | CDD | cd00275 | C2_PLC_like | coord: 732..856
e-value: 3.44402E-45
score: 158.474 |
| IPR000980 | SH2 domain | PRINTS | PR00401 | SH2DOMAIN | coord: 236..247
score: 32.2
coord: 382..396
score: 38.6
coord: 363..373
score: 29.91
coord: 203..217
score: 48.44
coord: 224..234
score: 54.26 |
| IPR000980 | SH2 domain | SMART | SM00252 | SH2_5 | coord: 311..399
e-value: 3.9E-25
score: 99.5
coord: 201..290
e-value: 1.3E-30
score: 117.7 |
| IPR000980 | SH2 domain | PFAM | PF00017 | SH2 | coord: 203..284
e-value: 7.2E-24
score: 83.6
coord: 313..393
e-value: 1.7E-16
score: 60.0 |
| IPR000980 | SH2 domain | PROSITE | PS50001 | SH2 | coord: 313..408
score: 19.332 |
| IPR000980 | SH2 domain | PROSITE | PS50001 | SH2 | coord: 203..302
score: 21.497 |
| IPR000980 | SH2 domain | SUPERFAMILY | 55550 | SH2 domain | coord: 198..305 |
| IPR000980 | SH2 domain | SUPERFAMILY | 55550 | SH2 domain | coord: 290..409 |
| IPR001192 | Phosphoinositide phospholipase C family | PRINTS | PR00390 | PHPHLIPASEC | coord: 90..107
score: 50.21
coord: 652..673
score: 66.55
coord: 822..832
score: 42.54
coord: 673..691
score: 60.77 |
| IPR000008 | C2 domain | SMART | SM00239 | C2_3c | coord: 734..836
e-value: 1.1E-17
score: 74.8 |
| IPR000008 | C2 domain | GENE3D | 2.60.40.150 | | coord: 728..857
e-value: 3.8E-21
score: 74.9 |
| IPR000008 | C2 domain | PFAM | PF00168 | C2 | coord: 734..831
e-value: 2.2E-14
score: 53.5 |
| IPR000008 | C2 domain | PROSITE | PS50004 | C2 | coord: 734..821
score: 15.044 |
| IPR000008 | C2 domain | SUPERFAMILY | 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | coord: 735..855 |
| IPR001452 | SH3 domain | SMART | SM00326 | SH3_2 | coord: 441..496
e-value: 1.7E-9
score: 47.6 |
| IPR001452 | SH3 domain | PFAM | PF14604 | SH3_9 | coord: 445..493
e-value: 2.2E-8
score: 33.7 |
| IPR001452 | SH3 domain | PROSITE | PS50002 | SH3 | coord: 444..497
score: 9.388 |
| IPR001452 | SH3 domain | SUPERFAMILY | 50044 | SH3-domain | coord: 439..499 |
| IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | SMART | SM00148 | plcx_3 | coord: 1..106
e-value: 1.8E-26
score: 103.9 |
| IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | PFAM | PF00388 | PI-PLC-X | coord: 2..107
e-value: 2.4E-35
score: 121.1 |
| IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | PROSITE | PS50007 | PIPLC_X_DOMAIN | coord: 1..106
score: 35.966 |
| IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | SMART | SM00149 | plcy_3 | coord: 598..714
e-value: 7.8E-59
score: 211.4 |
| IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | PFAM | PF00387 | PI-PLC-Y | coord: 598..711
e-value: 2.2E-40
score: 137.5 |
| IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | PROSITE | PS50008 | PIPLC_Y_DOMAIN | coord: 598..714
score: 49.338 |
| IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain | GENE3D | 3.20.20.190 | | coord: 1..723
e-value: 6.3E-101
score: 337.2 |
| IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain | SUPERFAMILY | 51695 | PLC-like phosphodiesterases | coord: 2..220 |
| IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain | SUPERFAMILY | 51695 | PLC-like phosphodiesterases | coord: 562..725 |
| IPR035024 | PLC-gamma, N-terminal SH2 domain | CDD | cd10341 | SH2_N-SH2_PLC_gamma_like | coord: 198..294
e-value: 4.29055E-42
score: 149.038 |
| IPR035023 | PLC-gamma, C-terminal SH2 domain | CDD | cd09932 | SH2_C-SH2_PLC_gamma_like | coord: 308..417
e-value: 9.06123E-51
score: 173.22 |
| IPR011993 | PH domain-like | SUPERFAMILY | 50729 | PH domain-like | coord: 519..584 |
Blast
BLAST of TCONS_00026429-protein vs. Swiss-Prot (Human)
Match: PLCG1 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens GN=PLCG1 PE=1 SV=1) HSP 1 Score: 747.273 bits (1928), Expect = 0.000e+0 Identity = 409/886 (46.16%), Postives = 567/886 (64.00%), Query Frame = 0
Query: 1 RMGCRSIELDLWDGQTD-PIIYHGLTLTSKIKLVDVVQVIASNAFEVTPYPLILSLENHCTIPQQIKMANMFKKYFGKSLVTQYLDANEKQLPSPESLKYKVILKYKKIDQGQSDVFLSSLNSRDSAIWDDTLLSSSLKTGLVYMEDE-EKKWNKHLFVLTQTSIHYSFEQETTTQDDEDEDEIVETQEQNKDGNEDELHFSEKWFHRNIS-----RVEAEKLLREY--QKG--DGSFLVRPSNMFVGDFSLSFWRQNKVQHCRIKLRQTQDGSTKYFLVGQKSFDNLWSLINHYQLNPLRSDQFEMTLNEPIPQPNAHIGKPWYHDNLTRQQAEDMLKRMRKDGYFLVRKRMGSNELDPDSDSYAISFRTAGSIKHCVIKKEGRLFMIGSAPFESLVELISHYEKFALYRQTKLKFPCNQEVVKELGI-NPD---LEEEAPDSFYALPNAT-THKPACLAKYDYIG-KDDELKFPKGAMITNVVKFDGGWWRGDYNGQVQKWFPVNFTEETVIKEKAPVS-QQEIESKQGGVMLEEMQKGVIDLTGCQQQLL-QSQPSRPYIFSIKSQSGV---FNCSVESEHEMIEWVTAIQDASTKAQESSSQLKQLVEQRKIAKELSDLIVYCVTVPFNEE--GFENGKYYQMSSFPELKAERFVSRKTVDLRFLRLNHRQLSRVYPKGTRFDSSNYDPVIFWNFGCQMVALNYQTPDRSMQIERGTFLDNGGCGYVLQPDILRDPNFNPYDPTTFNKLVEPLNLRLTIIGARHLPKTGRGLTSPFVEVEIVGLSYDCRSFQTKTKQDNGLCPTWFER-LEFDVICPPLAKIRFVVHDEDMFGDPNFVAQACFPVTTLRPGHRSIPLKNAYSEEIPLAALLIELEIKNAQED 861
RMGCR IELD WDG P+IYHG TLT+KIK DV+ I +AF + YP+ILS+E+HC+I QQ MA FKK G +L+T+ ++ + LPSP LK K+++K+KK+ +G + + + S ++ + +S+S+K G++Y+ED +W H FVLT + I+YS E+ ++ Q +EDE+E E ELH +EKWFH + R AE+LL EY + G DGSFLVR S FVGD++LSFWR KVQHCRI RQ G+ K+FL FD+L+ LI HYQ PLR ++FEM L+EP+PQ NAH K WYH +LTR QAE ML R+ +DG FLVRKR N SYAISFR G IKHC +++EG+ M+G++ F+SLV+LIS+YEK LYR+ KL++P N+E ++++G PD L E FY N T K A A +DY ++DEL F K A+I NV K +GGWWRGDY G+ Q WFP N+ EE V PV+ + E E L ++ +GV+D+ CQ + + + +R ++FSI S + + +S+ E+ +WV I++ + A ++ K + ++KIA ELS+L+VYC VPF+EE G E Y MSSFPE KAE++V+ K +FL+ N QLSR+YPKG R DSSNYDP+ W G Q+VALN+QTPD+ MQ+ + F+ CGYVLQP +RD F+P+D ++ L EP + + ++GARHLPK GRG+ PFVE+E+ G YD +T+ DNGL P W + F + P A +RFVV++EDMF D NF+AQA FPV L+ G+R++PLKN YSE++ LA+LLI+++I A+E+
Sbjct: 358 RMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPT-----SMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYS-EETSSDQGNEDEEEPKEVSSST------ELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDA-GTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPN-------SYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMV----NPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVN-KAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGL-EPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKEN 1217
The following BLAST results are available for this feature:
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