TCONS_00027288-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00027288-protein vs. Swiss-Prot (Human)
Match: LYST (Lysosomal-trafficking regulator OS=Homo sapiens GN=LYST PE=1 SV=3)

HSP 1 Score: 877.085 bits (2265), Expect = 0.000e+0
Identity = 554/1533 (36.14%), Postives = 838/1533 (54.66%), Query Frame = 0

Query: 2027 TPDVLYHLRLGLMQLLKNTLMLLPDYLVTRVFGTILKVEHLLVLVNQTSDKLREVALENLIVYLQRGGRDCLANFNRFKGCHLLANQLHQHPITMRIVESCIQLLISKPVSLNSSLTKSLEMNEENVCYQ--AIVPCLTLLEGSIQRPVIFGHLVKFLLKVFDWVENLPLIAFDHGLAEIVSNIVCGLANEESGGVMTSWKKESFGHLLLLLDWLVDKACRTCQTLYFQMYKDLQLSLEHVDGREKEKKGHTSSSLLSKTCRFLKYYL--IQSALNVFQKNDLYRMNTKGDPQFLIANDVYETGNKAG------TAARSLIKRLRGGA----QILPQ-------PTIATPTEVQERLQDILSEAVKLATLFAKHEQTTDVFMFGCKLKCLGSGSEHKMTC--TDADQE------------FCKDLFEWFCINLQMILSSKSENTS---WCSLLKSIKEEVIAQASHLFINFVSPLRSQDLRLHFVRQYMKYKENKHMVPIFLLTHLLSKRREKFLACLNSILSIPHSQLSE---GDVDMLKKFKKSIGKINLVKMNDQKL-LTEMTEIKHKRKEEEMIKRRESYKRILERNSQ-LCRSIADNGMEVSKVIVE-------EQDRQRQKLLRVVRGKVSKDVEIRKTWRNLIHHVTQERALWYHKESYPCSWQLDPTEGPSRMRKRLQRCHLEIAPKFFMEDAPAKKLSHQKGLLSYLFTEHMDGEQPCFYSF----KTNDTIRFLYHCKRVTPATKNSGEVLIGETHMYFVGDEILADNNVTQAFFGDKDVISISWRYEEIHEILKRRYSLQDNALEIFLTSGRTFLLAFENTKSRDEVYEQLYSRELPNLATATMDLATLTTRWKEGHITNFEYLTELNKKAGRSFNDLMQYPVLPFIIADYESPILDLTNPTSFRNLIKPIACQDKGKEERYIENYEYLKADY-EHRKLDDPENATPPYHYSSHYSNSGTVLHFLVRLPPFTSMFLKYQDNQFDIPDRTFHSMGTTWKLSSFISNTDVKELIPEFFFLQEFLQNGERYDMGLRQNKKRVDNVHIPVWAKNNPRLFTLIHMQALESSIISGNIHHWIDLVFGFKQTGPAAIKATNVFHPATYFGVDVTSIKDAIHRRALETMIETYGQTPLQLFVNPHPKRFSKAAPSIMEILPQSMESMILSLPKEKETPSPKNEQMLLPEVFKSPLDSVVGIQWGDYCGSKSHLAPVVQWVQTLNFPAQRIISASSSLAAYLC--QENTCVL--------TRTALTNVVKPIGILSWGAKDSLLQVQS-SSTPMKSFFNPMRPDHVTCCEFIPELDVLFVGGLSGILNVWPVRFFLSKPSLDVVGAKQNLLGHSDCITSICICQPYSVAVTTSKDKTAIIWDLNRLCYIRSIEGHESTVQCAAVSEASGDIATACNQDLHGI-LYLWTINAKPVGRLKTDSHIRCLAFSTLPDGIAINVVAAGLQNGHIKMWDTWTLNPVRTMML-NSCEPVTAMSFSKWNPLHFFSADQRGNVYLWTSKDITLNKPPNFH 3491
            T D L  +  GL +LL   L++LPD L+  V   +++ + LLVLVN  S  +++  ++ L  Y  R  ++    F + +G  LLANQL+ H  T  ++E  I++   + + L+      LE       +Q  +++P L L+E S+   ++  + +  LL++ +    +  +  D+GL  ++ N V  L   E    M+ +K  +     L +   +  AC +  + YF++ +DL + L ++   +  K   T +  ++   R L+  +  I++  N   +N    + +   P   +   V +  + AG          SL+ ++R  A     ++ Q       P+ AT TE+ +RLQ +   AV        +    D+      L+   + ++ K +   T+  +E            F K++F +     ++ + S   + S   W  +L S KE    Q   L ++ +SP  +   R       + ++ N   +    L+  L +   K +  L+ ++     +L+E   G  ++L    K  G   +      K  L +M + + K+ E E    + ++++ +  N Q L + +     ++SK+  +        Q  +R+K+++ +RG    D+   + W+ LI  +T +RA+WY    YP SWQLDPTEGP+R R+RLQRC+L I  K+ + D   K     K  LSYLF    D     F S       +++IR    C  V P+ + +GE+L+G+  MYFV D   +D   + +  G+ +  S SW YEEI E+ KR + L+DNA+EIFLT+GRT LLAF+NTK RD+VY  + +  LPNL     ++  LT  W  G ITNFEYLT LNK AGRSFNDLMQYPV PFI+ADY S  LDL +   +RNL KPIA Q K KE+RY++ Y+YL+ +Y +  + DDP     PYHY SHYSNSGTVLHFLVR+PPFT MFL YQD  FDIPDRTFHS  TTW+LSSF S TDVKELIPEFF+L EFL N E +D G+RQN +RV++V++P WA+N+PRLF LIH QALES  +S NI  WIDLVFG+KQ G A+++A NVFHPATYFG+DV++++D + RRALETMI+TYGQTP QLF   H  R   A  +I   LP ++  ++    +E         + +    + SPL  + G++WG+Y GS S   PVV + Q      +R  S  +     +C    N C+L         R+  +  ++   ILSWG  D++L+++S  S P  +F    +   VT C ++P+   LF G   G++  +  RF  S PS   +  + +L GH++ ITS+ +C+PYS+ ++ S+D T IIWDLNRLCY++S+ GH+S V   + SE SGDIAT C+    G  L LWT+N   VG +     I  +AFS  P+G++INV+A GL+NG +++W TW L PVR +    S +P+ +++FS  +  H ++A+  G V  W  KD    K P F+
Sbjct: 2296 TEDCLVPICCGLYELLSGVLLILPDVLLEDVMDKLIQADTLLVLVNHPSPAIQQGVIKLLDAYFARASKEQKDKFLKNRGFSLLANQLYLHRGTQELLECFIEMFFGRHIGLDEEF--DLEDVRNMGLFQKWSVIPILGLIETSLYDNILLHNALLLLLQILNSCSKVADMLLDNGLLYVLCNTVAALNGLEKNIPMSEYKLLACDIQQLFIAVTI-HACSSSGSQYFRVIEDLIVMLGYL---QNSKNKRTQNMAVALQLRVLQAAMEFIRTTANHDSENLTDSLQSPSAPHHAV---VQKRKSIAGPRKFPLAQTESLLMKMRSVANDELHVMMQRRMSQENPSQATETELAQRLQRLTVLAVNRIIYQEFNSDIIDI------LRTPENVTQSKTSVFQTEISEENIHHEQSSVFNPFQKEIFTYLVEGFKVSIGSSKASGSKQQWTKILWSCKETFRMQLGRLLVHILSPAHAAQERKQIFE--IVHEPNHQEILRDCLSPSL-QHGAKLVLYLSELIHNHQGELTEEELGTAELLMNALKLCGHKCIPPSASTKADLIKMIKEEQKKYETEEGVNKAAWQKTVNNNQQSLFQRLDSKSKDISKIAADITQAVSLSQGNERKKVIQHIRGMYKVDLSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYLLRDR-QKSEDVVKPPLSYLFE---DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNA-SDTVESSSLQGELEPASFSWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRDDVYHNILTNNLPNLLEYG-NITALTNLWYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYFGMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSR-PGAKLNIEGELPAAVGLLVQFAFRE-------TREQVKEITYPSPLSWIKGLKWGEYVGSPSAPVPVVCFSQP---HGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQSEPPVNFIQSSQQYQVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHCREIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFS-CDGHHLYTANSDGTVIAWCRKDQQRLKQPMFY 3792          

HSP 2 Score: 171.014 bits (432), Expect = 8.308e-42
Identity = 215/916 (23.47%), Postives = 378/916 (41.27%), Query Frame = 0

Query:  945 EEQGYEADQDS---DDSTENQGS--QQSAPLFVMEKANTSVVGKTTQTFHKIKHPWLILVLLSELYNHIKDEKCVEFMRVVKLFLKKVFENQLLNVTNNTTLQQEGLLSILLDFYGVIFSQPDNNETIEIQDLLGKMIVHLSINSISPTDLKKLFSIFKLEDMNKVQLSKIVLEIAKEAKKKDGPQYHLSFP---APLLKDSQSGTQSKLLHRTQTFMIPKQEPAFRQSQLRSHSLSSMYEVRGDTLKPISYSNQPSSWESSAIHLPLASHFDWP--DKEFSICLWYMLEDNAIKTFHKETSFGEKARHNSIKLI-------SQQSHESYGCEEL-----------YHLVSFGAQHAMFEVWIGARTGYFQFRWITSCYGTPSDEQLMTFDQAFVQHHSQKN-----KWNQLILSLVLPSEPHTAEIVSFLNGIQISSVQMKYPSKFVQSQTKLSLLVGHGIKDDENVS----SNPSLKDKSNNTLKTGVIMVFQGKDSFMNKTGHHAATTKKWN-------NKPLIDQMKAVYLCQLGSNSTTINTEYQEYFSNQTASHMDSSLDWDSIVFKELSFCMGIINEQLVADKFPMQLLESPMEVLGDIKTKLQSSLMLTYNPRNIKEFSQYTPQLKTSGNIQHTILSELNPSEVLTKEGTVLPTTLFCNIATQEVESFKNTIHTCGGMSILLYLHAMVSEQQYSEEAQCSILKTIFSVQETCPYLLREMNDMAGYILIKRAIEQSPCDLNASLMKTLLEATCDGDLFLPSDDEDDLESAITINQNTRAVVKNVCILQMLLKDWTLIRKADFEVQEILWQGLETLVRPTHPHFKFNVAQFQRARVVENLLIGCQEVQQEKYFQL---PQSICKLFIGVITNLLGQPVDLPVLKAVCSFLIAIHPTLDTLTLHSASNFYL 1813
            EE+GYEAD +S   D  T++ G   +     F    +   ++   TQ   +I +P + ++ L+ L       K      V + FLK + + +     N   L Q+G +  LL  +  I +Q D+++    Q +L  ++V L  +     +L  L  IF LE     ++  + +    E+     P  +L+FP   AP L +  S  +   +  ++   + ++    R S+ +  +    +  R             SSW  + +HLPL     WP   + FS+ LW+ +E   I      T  G+K +  +  LI         +S    G E +            H++S G++  M +VW         FR    C  +  D + +   Q      SQ+N     KW  L+L+                         ++ P    +   K+S+ V    K D  +        SL   SN T    +      ++ F+   G       KW+       N   +   +A YL   G N T++              +     D+   + KE+  C  I    +      + LL   +E L  + T        TY P    +++ Y P ++  G ++ T LS+  P      +  +L      N+   E ++ +  +H  GG  I ++L A V E    EE Q   L+ I S+ +     + E+ +  G  +I + + +  C +   ++KTLLE  C  D+   +++ +       ++ ++ A++++V +L+ LL DW +  KA+  V E L   LE L+R  H    FN+ Q  +A+VV + L+ CQ +Q+ K  QL   P+ +C+ F+ +I  +LG P DL +L  + +FL+A+HP  +T   H+ +NFY 
Sbjct: 1217 EEEGYEADSESNPEDGETQDDGVDLKSETEGFSASSSPNDLLENLTQG--EIIYPEICMLELNLL--SASKAKLDVLAHVFESFLKIIRQKE----KNVFLLMQQGTVKNLLGGFLSILTQ-DDSDFQACQRVLVDLLVSLMSSRTCSEELTLLLRIF-LEKSPCTKILLLGILKIIESDTTMSPSQYLTFPLLHAPNLSNGVSSQKYPGILNSKAMGLLRRA---RVSRSKKEADRESFPHR-----------LLSSWHIAPVHLPLLGQNCWPHLSEGFSVSLWFNVE--CIHEAESTTEKGKKIKKRNKSLILPDSSFDGTESDRPEGAEYINPGERLIEEGCIHIISLGSKALMIQVWADPHNATLIFR---VCMDSNDDMKAVLLAQV----ESQENIFLPSKWQHLVLTY------------------------LQQPQGKRRIHGKISIWVSGQRKPDVTLDFMLPRKTSLSSDSNKTF-CMIGHCLSSQEEFLQLAG-------KWDLGNLLLFNGAKVGSQEAFYLYACGPNHTSV----------MPCKYGKPVNDYSKYINKEILRCEQIRELFMTKKDVDIGLL---IESLSVVYT--------TYCP---AQYTIYEPVIRLKGQMK-TQLSQ-RPFSSKEVQSILLEPHHLKNLQPTEYKTIQGILHEIGGTGIFVFLFARVVELSSCEETQALALRVILSLIKYNQQRVHELENCNGLSMIHQVLIKQKCIVGFYILKTLLEGCCGEDIIYMNENGE-----FKLDVDSNAIIQDVKLLEELLLDWKIWSKAEQGVWETLLAALEVLIRADHHQQMFNIKQLLKAQVVHHFLLTCQVLQEYKEGQLTPMPREVCRSFVKIIAEVLGSPPDLELLTIIFNFLLAVHPPTNTYVCHNPTNFYF 2036