TCONS_00027468-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00027468-protein
Unique NameTCONS_00027468-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length958

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00027468-protein ID=TCONS_00027468-protein|Name=TCONS_00027468-protein|organism=Clytia hemisphaerica|type=polypeptide|length=958bp
MSTNEIREEKYLHTGYLSKDGTFDKQNNDAISGYYILTRGLLECYKSLKL
QKLKRSYNLATITDIATINKNTFKICLLGSKTLIFQTKDQNDCVAWVSHL
EQGFQLWNSCSLSDKVETDVEQEVFCHRITFPSILLPNQIRKDEDGQTKG
EFHMIKYARNGKTIPHERVFKMDDNNLHVMWKKTRQSSSYRWKSCLNIQD
ISEVRCGQQTRNFNLFPYVEVDKQSFSLIFERDREEWCGLCSLDVICDSV
LAFQDWKKTLDHLIYEKNGKKPSRDSQKLNDPIKTFLKRHWSLLAVDNKV
ISLDTTANFLSQCDQKFKKRSLRNFLRRITKNNFSRDEIPWDGFLFTFNV
INDQPKLLHIYSKYALTFPDLGLTVQEFQKFLQFEQNDGDVTASVVRQLI
DYHDRDHWIFKRVSAGGDPNAYHNSAKLLSFHGFVSYLRSADNDVINHKV
KQDMTKPLSHYFINSSHNTYLTTHQLKGLSSCEAYIYALQKGCKCLEIDC
WDGPDGPIVTHGMTFTSKIPLKDVLTIIKVYGFDYSPYPVILSLENHCSA
EQQAMMAQMFTEIFGDTIATDNLCNLNNLPSPEQLKYKIILKGNLKSKKK
MRQRKISKQTTKKRSASISSATSANFSPKYLEKTDEVSQTPGLKTQRSIS
VNSMTSFNSPSQHSPQMNEASNEEKTGDSEQVQIPFEASMARLIVYCISV
PYKHGETNPNCCEMHSFSENQISTLVEKCPLEMIYLTQRKFIRTYPKASR
VDSSNYNPMLSWRHGIQMAAINVQKPDNGFYINDGLFIKSNGTGYVLKPS
QMTTKGSTYHPQMTKPATGDYSQRMKIEIFCGQFVESEHFTDLPVAIEME
IIGAVEKDCQSFYTEPSNNLFNPVWERSTFTFDLSLPSMCLLLVKVVSVS
RVNRLVYQTCLPVDLLKTGVRYIPMKSPTGVLRPENGIFVHLSSTIGSVL
KAQNFATR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_015478XLOC_015478Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00027468TCONS_00027468Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001192PI-PLC_fam
IPR001711PLipase_C_Pinositol-sp_Y
IPR001849PH_domain
IPR000909PLipase_C_PInositol-sp_X_dom
IPR015359PLC_EF-hand-like
IPR011993PH_dom-like
IPR017946PLC-like_Pdiesterase_TIM-brl
IPR011992EF-hand-dom_pair
IPR000008C2_dom
Vocabulary: Biological Process
TermDefinition
GO:0035556intracellular signal transduction
GO:0007165signal transduction
GO:0006629lipid metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0004435phosphatidylinositol phospholipase C activity
GO:0008081phosphoric diester hydrolase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0006629 lipid metabolic process
biological_process GO:0007165 signal transduction
molecular_function GO:0004435 phosphatidylinositol phospholipase C activity
molecular_function GO:0008081 phosphoric diester hydrolase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 952..958
NoneNo IPR availableGENE3D1.10.238.10coord: 348..449
e-value: 2.6E-12
score: 46.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 596..680
NoneNo IPR availableCDDcd00275C2_PLC_likecoord: 823..943
e-value: 6.97218E-20
score: 86.4412
NoneNo IPR availableCDDcd08558PI-PLCc_eukaryotacoord: 452..787
e-value: 8.58301E-102
score: 318.626
IPR001192Phosphoinositide phospholipase C familyPRINTSPR00390PHPHLIPASECcoord: 911..921
score: 43.91
coord: 483..503
score: 52.38
coord: 578..595
score: 47.69
coord: 762..780
score: 41.11
coord: 741..762
score: 54.55
coord: 457..475
score: 74.58
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainSMARTSM00149plcy_3coord: 690..803
e-value: 5.3E-38
score: 142.3
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainPFAMPF00387PI-PLC-Ycoord: 691..800
e-value: 6.9E-30
score: 103.6
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainPROSITEPS50008PIPLC_Y_DOMAINcoord: 690..802
score: 33.978
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 146..267
e-value: 13.0
score: 11.3
coord: 11..107
e-value: 8.5E-5
score: 31.9
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 13..102
e-value: 2.1E-6
score: 28.1
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 10..105
score: 7.649
IPR000909Phosphatidylinositol-specific phospholipase C, X domainSMARTSM00148plcx_3coord: 452..594
e-value: 7.7E-84
score: 294.5
IPR000909Phosphatidylinositol-specific phospholipase C, X domainPFAMPF00388PI-PLC-Xcoord: 454..593
e-value: 9.1E-60
score: 200.4
IPR000909Phosphatidylinositol-specific phospholipase C, X domainPROSITEPS50007PIPLC_X_DOMAINcoord: 452..593
score: 53.707
IPR015359Phosphoinositide-specific phospholipase C, EF-hand-like domainPFAMPF09279EF-hand_likecoord: 353..447
e-value: 1.2E-4
score: 22.4
IPR011993PH domain-likeGENE3D2.30.29.30coord: 1..119
e-value: 5.9E-10
score: 38.1
IPR011993PH domain-likeGENE3D2.30.29.30coord: 152..266
e-value: 1.7E-9
score: 37.4
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 10..111
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 156..264
IPR017946PLC-like phosphodiesterase, TIM beta/alpha-barrel domainGENE3D3.20.20.190coord: 450..814
e-value: 9.7E-113
score: 376.1
IPR017946PLC-like phosphodiesterase, TIM beta/alpha-barrel domainSUPERFAMILY51695PLC-like phosphodiesterasescoord: 452..611
coord: 648..803
IPR011992EF-hand domain pairSUPERFAMILY47473EF-handcoord: 297..449
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 855..941

Blast
[Close]
BLAST of TCONS_00027468-protein vs. Swiss-Prot (Human)
Match: PLCD4 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 OS=Homo sapiens GN=PLCD4 PE=2 SV=1)

HSP 1 Score: 287.345 bits (734), Expect = 3.348e-84
Identity = 232/825 (28.12%), Postives = 387/825 (46.91%), Query Frame = 0 
Query:  135 LLPNQIRKDEDGQTKGEFHMIKYARNGKTIPHERVFKMDDNNLHVMWKKTRQSSSYRWKSCLNIQDISEVRCGQQTRNFNLFPYVEVDKQSFSLIFERDREEWCGLCSLDVICDSVLAFQDWKKTLDHLI-YEKNGKKPSRDSQKLNDPIKTFLKRHWSLLAVDNKVISLDTTANFLSQCDQKFKKRSLRNFLRRITKNNFSRDEIPWDGFLFTFNVINDQPKLLHIYSKYALTFPDLGLTVQEFQKFLQFEQNDGDVTASVVRQLIDYHDRDHWIFKRVSAGGDPNAYHNSAKLLSFHGFVSYLRSADNDVINHK---VKQDMTKPLSHYFINSSHNTYLTTHQLKGLSSCEAYIYALQKGCKCLEIDCWDGPDG-PIVTHGMTFTSKIPLKDVLTIIKVYGFDYSPYPVILSLENHCSAEQQAMMAQMFTEIFGDTIATDNLCNL--NNLPSPEQLKYKIILKGNLKSKKKMRQRKISKQTTKKRSASISSATSANFSPKYLEKTDEVSQTPGLKTQRSISVNSMTSFNSPSQHSPQMNEASNEEKTGDSEQVQIPFEASMARLIVYCISVPYK---HGETNPNCCEMHSFSENQISTLVEKCPLEMIYLTQRKFIRTYPKASRVDSSNYNPMLSWRHGIQMAAINVQKPDNGFYINDGLFIKSNGTGYVLKPSQMTTKGSTYHPQMTKPATGDYSQRMKIEIFCGQFV----ESEHFTDLPVAIEMEIIGAVEKDCQSFYTEPSNNLFNPVWERSTFTFDLSLPSMCLLLVKVVSVSRVNR--LVYQTCLPVDLLKTGVRYIPMKSPTGV-LRPENGIFVHL 942
            LL +Q+  D+D     E   ++  R+ K+    R F++ ++ + V   +  + S+   K   +I D+  +R G  +            +Q F+++F   R       +LD++ +SV   Q W + L  L+    +     R  Q L+D  +   K        D K +S       L   + +  +    +  +    +      +  + F+  +  +  + ++  ++  ++       LT+ EF  FLQ EQ + D T+ +  +LID ++              P+       +LS  GF+SYL S D D+ N     + QDMT+PL+HYFI SSHNTYL   QL G SS E YI AL++GC+C+E+D WDGP G P+V HG T TS+I  KDV+  +  Y F  S YPVILSLE HCS EQQ  MA+  TEI G+ + +  L  +    LPSPE+L+ KI++KG   + ++  + +  +   +   + ++  +     P+                                   PQ     N++K   S+ +  P  +S+   ++Y  SV ++   H + + +  E+ SFSE +   L+++   E +     +  R YP   R DSSNYNP   W  G QM A+N+Q       I DG F ++ G GYVLKP  +    S++HP+  KP +   +Q + I++  GQ +    +++  + +   ++++I G      +       NN FNP W + T  F + +P + +L   V+     +R   + Q  LP   ++ G R+I + S  G+ LRP + IFV++
Sbjct:    4 LLQDQLTTDQDLLLMQEGMPMRKVRS-KSWKKLRYFRLQNDGMTVWHARQARGSA---KPSFSISDVETIRNGHDSELLRSLAEELPLEQGFTIVFHGRRS------NLDLMANSVEEAQIWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQ------DGK-MSFQEVQRLLHLMNVEMDQEYAFSLFQ--AADTSQSGTLEGEEFVQFYKALTKRAEVQELFESFSAD--GQKLTLLEFLDFLQEEQKERDCTSELALELIDRYE--------------PSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQLPSPEELRRKILVKGKKLTLEEDLEYEEEEAEPELEESELALESQFETEPE-----------------------------------PQEQNLQNKDKKKKSKPILCPALSSL---VIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDIQSSFHPE--KPISPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDTARQETNYVENNGFNPYWGQ-TLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQGYRHIHLLSKDGISLRPAS-IFVYI 751
The following BLAST results are available for this feature:
BLAST of TCONS_00027468-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PLCD43.348e-8428.121-phosphatidylinositol 4,5-bisphosphate phosphodie... [more]
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