TCONS_00028072-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00028072-protein
Unique NameTCONS_00028072-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length423

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00028072-protein ID=TCONS_00028072-protein|Name=TCONS_00028072-protein|organism=Clytia hemisphaerica|type=polypeptide|length=423bp
MEMLKILFCLTLCCFGVIAGEVMASLKNINMTNYEKVSLPYIAEQNKTVD
VNVSMYILNIGNLNTQEMTFEVEMYFGMKWKDPRLAFKEYNNASYALVTG
ETAYDNIWVPDLFIRNMKHVESSTFLKDLSGVMIYPDGIVSLSSRIRVVA
HCEMDLLMFPLDSQSCNLMIESYLYHTDVMKMYWAENPVVIDDRRDGRKT
EIDTWNGFTLEEVKTTEDSYIYPINKLEFKNMIATFVLKREPQYYILRGF
IPSSLLVCLTWASFWLPTSSYPARVALIVTSFLASIVLYQGSTLHSIQMT
VMQVFLFGNISFIMVTLMEFLMAVKADHEKKEKTELVPTIRNEIFNSANE
TQENEFWPKEKKNMTSAVDVGKNQTNENERKSTTRNKEKTENSVDRKARF
IIPILYFIYVGVFVAALFFLNQE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_015883XLOC_015883Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00028072TCONS_00028072Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006028GABAA/Glycine_rcpt
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 106..117
score: 44.65
coord: 71..87
score: 31.17
coord: 236..248
score: 33.87
coord: 152..166
score: 49.74
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alphaPRINTSPR00253GABAARECEPTRcoord: 271..292
score: 34.71
coord: 245..265
score: 41.72
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 21..245
e-value: 1.3E-42
score: 145.2
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 31..242
e-value: 6.3E-37
score: 127.0
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 26..242
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 251..389
e-value: 5.2E-7
score: 29.9
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 242..419
NoneNo IPR availableGENE3D1.20.58.390coord: 246..423
e-value: 1.2E-23
score: 83.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 367..390
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 152..166

Blast
BLAST of TCONS_00028072-protein vs. Swiss-Prot (Human)
Match: GBRR1 (Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapiens GN=GABRR1 PE=2 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 1.358e-34
Identity = 100/388 (25.77%), Postives = 190/388 (48.97%), Query Frame = 0
Query:   49 VDVNVSMYILNIGNLNTQEMTFEVEMYFGMKWKDPRLAFKEYNNASYALVTGETAYDNIWVPDLFIRNMKHVESSTFLKDLSG----VMIYPDGIVSLSSRIRVVAHCEMDLLMFPLDSQSCNLMIESYLYHTDVMKMYWAENPVVIDDRRDGRKT-EIDTWNGFTLEEVKTTEDSYIYPINKLEFKNMIATFVLKREPQYYILRGFIPSSLLVCLTWASFWLPTSSYPARVALIVTSFL--ASIVLYQGSTLHSIQ-MTVMQVFLFGNISFIMVTLME-----FLMAVKADHEKKEKTEL-----VPTIRNEIFNSA-NETQENEFWPKEKKNMTSAVDVGKNQTNENERKSTTRNKEKTE--------NSVDRKARFIIPILYFIY 409
            + V V + + ++ +++  +M F + +Y    WKD RL+F   NN S  +         IWVPD+F  + K     +F+ D +     + + PDG V  S R+ V A C MD   FPLD+Q+C+L IESY Y  D + +YW +         D  KT E  + + F ++E  TT     Y      +  +   F L+R   +++L+ + P++L+V L+W SFW+   + PARV L +T+ L  ++I+    +++  +  +  + ++L+ +  F+ ++++E     +L  V+   E+K + +L     +P  R  + +   ++ + N+      +N      +    T  +ER S  R  +++         +++D+ +R I P  Y ++
Sbjct:   97 IPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLS--MTFDGRLVKKIWVPDMFFVHSKR----SFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKG-------NDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGW-YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILF 470          
The following BLAST results are available for this feature:
BLAST of TCONS_00028072-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GBRR11.358e-3425.77Gamma-aminobutyric acid receptor subunit rho-1 OS=... [more]
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