TCONS_00029362-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00029362-protein
Unique NameTCONS_00029362-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length380

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00029362-protein ID=TCONS_00029362-protein|Name=TCONS_00029362-protein|organism=Clytia hemisphaerica|type=polypeptide|length=380bp
MSNSSTNDAGSSKLPEADDKEDGISNDVTNQDGGASGGAGAITEESARDR
LFEYFKTLGISTNQTEEKHEKVISSLTIEGIAEHIRELRCKNIIVMTGAG
ISTSAGIPDFRSPGTGLYSKLEKYNLPYPQAIFELDYFKENPDPFFLLAK
ELYPGNFQPTPSHRFIKLLHENGLLLRNYTQNIDGLEVVAGVPQDKIVAA
HGTFMTSHCIGCEKEYSESWMREKIFASELPICESCGGTVKPDIVFFGEN
LPLRFFTCMGQDFRKADLLIVMGTSLTVQPFASLINRVGDHVPRLLINKE
KCGQSFFSGGFDFDGPNSYRDVALLGDCDEGCSKLSELLGWKDDLERLME
GLEIEKSQESCSEDSHPDPPEIVVNETDSS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_016745XLOC_016745Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00029362TCONS_00029362Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR017328Sirtuin_class_I
IPR029035DHS-like_NAD/FAD-binding_dom
IPR003000Sirtuin
IPR026590Ssirtuin_cat_dom
Vocabulary: Molecular Function
TermDefinition
GO:0017136NAD-dependent histone deacetylase activity
GO:0008270zinc ion binding
GO:0070403NAD+ binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0070403 NAD+ binding
molecular_function GO:0017136 NAD-dependent histone deacetylase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR017328Sirtuin, class IPIRSFPIRSF037938SIR2_eukcoord: 56..377
e-value: 3.1E-137
score: 455.2
IPR029035DHS-like NAD/FAD-binding domainGENE3D3.40.50.1220coord: 70..350
e-value: 1.2E-84
score: 283.1
IPR029035DHS-like NAD/FAD-binding domainSUPERFAMILY52467DHS-like NAD/FAD-binding domaincoord: 68..352
IPR003000Sirtuin familyPFAMPF02146SIR2coord: 98..280
e-value: 2.3E-57
score: 193.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..42
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 356..380
NoneNo IPR availableCDDcd01408SIRT1coord: 91..335
e-value: 4.97179E-146
score: 415.492
IPR026590Sirtuin family, catalytic core domainPROSITEPS50305SIRTUINcoord: 79..344
score: 52.266

Blast
[Close]
BLAST of TCONS_00029362-protein vs. Swiss-Prot (Human)
Match: SIR2 (NAD-dependent protein deacetylase sirtuin-2 OS=Homo sapiens GN=SIRT2 PE=1 SV=2)

HSP 1 Score: 377.481 bits (968), Expect = 1.107e-129
Identity = 189/349 (54.15%), Postives = 240/349 (68.77%), Query Frame = 0 
Query:   11 SSKLPEADDKEDGISNDVTNQDGGASGGAGAITEESARDRLFEYFKTLGISTNQTEEKHEKVISSLTIEGIAEHIRELRCKNIIVMTGAGISTSAGIPDFRSPGTGLYSKLEKYNLPYPQAIFELDYFKENPDPFFLLAKELYPGNFQPTPSHRFIKLLHENGLLLRNYTQNIDGLEVVAGVPQDKIVAAHGTFMTSHCI--GCEKEYSESWMREKIFASELPICESCGGTVKPDIVFFGENLPLRFFTCMGQDFRKADLLIVMGTSLTVQPFASLINRVGDHVPRLLINKEKCGQS--------FFSGGFDFDGPNSYRDVALLGDCDEGCSKLSELLGWKDDLERLM 349
            + K+ EA D +       ++ +GGA+GG   +          ++ + L   T     + E+++  LT+EG+A +++  RC+ +I + GAGISTSAGIPDFRSP TGLY  LEKY+LPYP+AIFE+ YFK++P+PFF LAKELYPG F+PT  H F++LL + GLLLR YTQNID LE +AG+ Q+ +V AHGTF TSHC+   C  EY  SWM+EKIF+   P CE C   VKPDIVFFGE+LP RFF+CM  DF K DLL+VMGTSL VQPFASLI++     PRLLINKEK GQS           GG DFD   +YRDVA LG+CD+GC  L+ELLGWK +LE L+
Sbjct:   14 AGKVQEAQDSD-------SDSEGGAAGGEADM----------DFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLV 345
The following BLAST results are available for this feature:
BLAST of TCONS_00029362-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SIR21.107e-12954.15NAD-dependent protein deacetylase sirtuin-2 OS=Hom... [more]
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