TCONS_00053165-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00053165-protein
Unique NameTCONS_00053165-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length413

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00053165-protein ID=TCONS_00053165-protein|Name=TCONS_00053165-protein|organism=Clytia hemisphaerica|type=polypeptide|length=413bp
MAKIPGGTVVELDGDEMTRVIWDMIKKQLILPFVDLDIKRYDLGMENRDA
TDDQVTHEAAAAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRN
ILGGTVFREAIICKNIPKLVPGWTKPIIIGRHAHADQYKATDFVVPGAGK
LEMKFTPSDGSAPMEYVVYDFNGGGVAMGMYNTDQSIRDFAYSSFNCALE
KSYPLYLSTKNTILKKYDGRFKDIFQEIYDKEYKEKFEKAGIWYEHRLID
DMVAYALKVDGGFVWACKNYDGDVQSDTVAQGYGSLGMMTSVLLCPDGKT
IEAEAAHGTVTRHYRQHQQGKETSTNPVASIFAWTRGLLHRGKLDSNDKL
TQFAKSLEETCVETIESGFMTKDLAICIKGGANKIVRADYLNTIEFIQKI
ADNLQVKLKAANL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033557XLOC_033557Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00053165TCONS_00053165Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR024084IsoPropMal-DH-like_dom
IPR004790Isocitrate_DH_NADP
IPR019818IsoCit/isopropylmalate_DH_CS
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006102isocitrate metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004450isocitrate dehydrogenase (NADP+) activity
GO:0051287NAD binding
GO:0000287magnesium ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006102 isocitrate metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0004450 isocitrate dehydrogenase (NADP+) activity
molecular_function GO:0000287 magnesium ion binding
molecular_function GO:0051287 NAD binding
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 394..413
NoneNo IPR availableGENE3D3.40.718.10coord: 5..413
e-value: 4.0E-136
score: 453.5
NoneNo IPR availableSUPERFAMILY53659Isocitrate/Isopropylmalate dehydrogenase-likecoord: 7..408
IPR024084Isopropylmalate dehydrogenase-like domainSMARTSM01329Iso_dh_2coord: 8..400
e-value: 1.0E-134
score: 463.5
IPR024084Isopropylmalate dehydrogenase-like domainPFAMPF00180Iso_dhcoord: 10..398
e-value: 1.4E-74
score: 251.3
IPR004790Isocitrate dehydrogenase NADP-dependentPIRSFPIRSF000108IDH_NADPcoord: 2..411
e-value: 1.6E-229
score: 759.3
IPR004790Isocitrate dehydrogenase NADP-dependentTIGRFAMTIGR00127TIGR00127coord: 6..409
e-value: 1.7E-228
score: 756.0
IPR019818Isocitrate/isopropylmalate dehydrogenase, conserved sitePROSITEPS00470IDH_IMDHcoord: 269..288

Blast
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BLAST of TCONS_00053165-protein vs. Swiss-Prot (Human)
Match: IDHC (Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens GN=IDH1 PE=1 SV=2)

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 309/412 (75.00%), Postives = 363/412 (88.11%), Query Frame = 0 
Query:    3 KIPGGTVVELDGDEMTRVIWDMIKKQLILPFVDLDIKRYDLGMENRDATDDQVTHEAAAAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPKLVPGWTKPIIIGRHAHADQYKATDFVVPGAGKLEMKFTPSDGSAPMEYVVYDFN-GGGVAMGMYNTDQSIRDFAYSSFNCALEKSYPLYLSTKNTILKKYDGRFKDIFQEIYDKEYKEKFEKAGIWYEHRLIDDMVAYALKVDGGFVWACKNYDGDVQSDTVAQGYGSLGMMTSVLLCPDGKTIEAEAAHGTVTRHYRQHQQGKETSTNPVASIFAWTRGLLHRGKLDSNDKLTQFAKSLEETCVETIESGFMTKDLAICIKGGANKIVRADYLNTIEFIQKIADNLQVKLKAANL 413
            KI GG+VVE+ GDEMTR+IW++IK++LI P+V+LD+  YDLG+ENRDAT+DQVT +AA AIKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIP+LV GW KPIIIGRHA+ DQY+ATDFVVPG GK+E+ +TPSDG+  + Y+V++F  GGGVAMGMYN D+SI DFA+SSF  AL K +PLYLSTKNTILKKYDGRFKDIFQEIYDK+YK +FE   IWYEHRLIDDMVA A+K +GGF+WACKNYDGDVQSD+VAQGYGSLGMMTSVL+CPDGKT+EAEAAHGTVTRHYR +Q+G+ETSTNP+ASIFAWTRGL HR KLD+N +L  FA +LEE  +ETIE+GFMTKDLA CIKG  N + R+DYLNT EF+ K+ +NL++KL  A L
Sbjct:    4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPN-VQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
The following BLAST results are available for this feature:
BLAST of TCONS_00053165-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IDHC0.000e+075.00Isocitrate dehydrogenase [NADP] cytoplasmic OS=Hom... [more]
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