TCONS_00061039-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00061039-protein
Unique NameTCONS_00061039-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length533

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00061039-protein ID=TCONS_00061039-protein|Name=TCONS_00061039-protein|organism=Clytia hemisphaerica|type=polypeptide|length=533bp
LSPFFDPDILFPPKKTCFVFLCFVILPSWTLNFRPQPADKNHLQGNCTLF
SFSILASSCTSPLNSAMDNQDYLRQPLKENDPEMYEIMKKEDERQRSGLE
MIASENFTSRAVFEALGSCFTNKYSEGKIGNRYYGGAQFIDEMEIVCKRR
ALAAFRLDDKEWGVNVQPYSGSPANFEVFTGLLQPHDRIMGLDLPDGGHL
THGYRTLTKKISASSIYFESMPYKVNQETGLIDYDKLLETAKLFQPKIII
AGASAYSRLIDYARFRKIADEVGALLMTDVAHYSGLVAAGAIPSPFEHSH
IVTTTTHKSLRGARSGMIFYRIGQKSVDKSGKPVMYDFADRIDMAVFPSL
QGGPHNNNIAAVAVALKQALTPEFKEYALQVIKNAQAMADLFTKKGYKVV
SDGTDTHMFLLDFRGQATDGAKVDIMLEICSMSVNRNTVPGDKSALRPSG
IRIGTSALTSRNFFEKDVEKVVEFIEEAIKLSIEVSSSLGKCTLKQYKEA
LQLETWKVKVDDLRQRVEAYALTFPMPGPPPLE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_038321XLOC_038321Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00061039TCONS_00061039Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR015422PyrdxlP-dep_Trfase_sub2
IPR001085Ser_HO-MeTrfase
IPR015421PyrdxlP-dep_Trfase_major_sub1
IPR019798Ser_HO-MeTrfase_PLP_BS
IPR015424PyrdxlP-dep_Trfase
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0004372glycine hydroxymethyltransferase activity
GO:0030170pyridoxal phosphate binding
Vocabulary: Biological Process
TermDefinition
GO:0006545glycine biosynthetic process
GO:0035999tetrahydrofolate interconversion
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006545 glycine biosynthetic process
biological_process GO:0035999 tetrahydrofolate interconversion
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004372 glycine hydroxymethyltransferase activity
molecular_function GO:0030170 pyridoxal phosphate binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015422Pyridoxal phosphate-dependent transferase, subdomain 2GENE3D3.90.1150.10coord: 367..527
e-value: 6.7E-60
score: 201.0
NoneNo IPR availablePFAMPF00464SHMTcoord: 77..475
e-value: 1.9E-190
score: 632.6
IPR001085Serine hydroxymethyltransferasePIRSFPIRSF000412SHMTcoord: 60..530
e-value: 1.3E-168
score: 558.8
IPR001085Serine hydroxymethyltransferaseHAMAPMF_00051SHMTcoord: 76..528
score: 42.099
IPR001085Serine hydroxymethyltransferaseCDDcd00378SHMTcoord: 78..480
e-value: 0.0
score: 605.351
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1GENE3D3.40.640.10coord: 106..366
e-value: 6.2E-40
score: 136.6
IPR019798Serine hydroxymethyltransferase, pyridoxal phosphate binding sitePROSITEPS00096SHMTcoord: 300..316
IPR015424Pyridoxal phosphate-dependent transferaseSUPERFAMILY53383PLP-dependent transferasescoord: 73..528

Blast
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BLAST of TCONS_00061039-protein vs. Swiss-Prot (Human)
Match: GLYM (Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens GN=SHMT2 PE=1 SV=3)

HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0
Identity = 281/457 (61.49%), Postives = 362/457 (79.21%), Query Frame = 0 
Query:   74 RQPLKENDPEMYEIMKKEDERQRSGLEMIASENFTSRAVFEALGSCFTNKYSEGKIGNRYYGGAQFIDEMEIVCKRRALAAFRLDDKEWGVNVQPYSGSPANFEVFTGLLQPHDRIMGLDLPDGGHLTHGYRTLTKKISASSIYFESMPYKVNQETGLIDYDKLLETAKLFQPKIIIAGASAYSRLIDYARFRKIADEVGALLMTDVAHYSGLVAAGAIPSPFEHSHIVTTTTHKSLRGARSGMIFYRIGQKSVD-KSGKPVMYDFADRIDMAVFPSLQGGPHNNNIAAVAVALKQALTPEFKEYALQVIKNAQAMADLFTKKGYKVVSDGTDTHMFLLDFRGQATDGAKVDIMLEICSMSVNRNTVPGDKSALRPSGIRIGTSALTSRNFFEKDVEKVVEFIEEAIKLSIEVSSSLGKCTLKQYKEALQLET-WKVKVDDLRQRVEAYALTFPMPG 528
            ++ L ++DPEM+E++++E +RQ  GLE+IASENF SRA  EALGSC  NKYSEG  G RYYGGA+ +DE+E++C+RRAL AF LD  +WGVNVQPYSGSPAN  V+T LLQPHDRIMGLDLPDGGHLTHGY +  K+ISA+SI+FESMPYK+N +TGLIDY++L  TA+LF+P++IIAG SAY+RLIDYAR R++ DEV A L+ D+AH SGLVAA  IPSPF+H+ IVTTTTHK+LRGARSG+IFYR G K+VD K+G+ + Y F DRI+ AVFPSLQGGPHN+ IAAVAVALKQA TP F+EY+LQV+KNA+AMAD   ++GY +VS GTD H+ L+D R +  DGA+ + +LE+ S++ N+NT PGD+SA+ P G+R+G  ALTSR F E D  +VV+FI+E + + +EV S   K  L+ +K  L  ++    ++ +LRQRVE +A  FPMPG
Sbjct:   46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAK--LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPG 500
The following BLAST results are available for this feature:
BLAST of TCONS_00061039-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GLYM0.000e+061.49Serine hydroxymethyltransferase, mitochondrial OS=... [more]
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