TCONS_00068492-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00068492-protein
Unique NameTCONS_00068492-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1056

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00068492-protein ID=TCONS_00068492-protein|Name=TCONS_00068492-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1056bp
MRSHLKELRRQSLPPTFFSKTNLKHPHLGLNNNSRRRCPSPDMSKEGDEN
VHVDTLRDTIKLEIRRELKIKEGAENLRKVSTDKRTLAQCQQAIKASSQK
LDELHDHLQDLNAHISEEIVMASGAGDPGKEILSPQKSMIAYKEDITDHY
GNNRMASLEKQLAIEMKVKQGAENMLQMLQGKDSKSKKMIAEAEQMLADS
KVKIDAIKMSILREQQSEKNTPETPNNRASLHEKSLEHRVDDIRHHIDIE
TRVAEGARNMLKHFLINSDKKGINEAEKTLVEATNKLDLLHMSLERRIAE
INPAAAQVGIYNEKLLPSPKSRQRLKAAAVTGKLEVKVLGAEHLLESVPN
RDPRKSNTIVASPDNKFRLSKRMSTSTYNSKTTDDSCLSDICAVLKLDNV
DVGHSKWKSKEAHCWNETFNISLDKARELEIGVYYRDYRSLCGITFLKLV
DFLDNQRHELKLSLEPVGTLRCEVTFFNPLVNRRPRLQRQKQLFPKAKGK
HFLRAGDMNTNIATWARLLKRAAPPSSQSFSPNAGGGSMSNSDISLNSNE
PTLVSSTSNIHSRSSSPGHHSASSSNHSSIQDISNAKNLSNQDLTRPTDR
PTSRELPSLDAIQRHETPPAAPISPPSTSPPPPVESNISPPPRQAATPTT
QTIAKEQKASIKSPSPPLDSQRPSSKSDPPKPTPAVPAHGKSSPKPELKS
IGRNSGRKSAGRSPPPRRSRSLTMSVDQFRHISVLGRGHFGKVLLAEYKT
TKELFAIKALKKGDIIFRDEVESLMSEKRIFEAANCVRHPFLVNLFACFQ
TKDHVCFVMEYAPGGDLMMHIHEEVFSEPRTMFYSGCVILGLQYLHDHEI
VYRDLKLDNLLLDAEGYVKIADFGLCKEGMGFGQKTGTFCGTPEFLAPEV
LTETSYTRSVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPR
FLSNDSIALMRRLLRKNPDRRLGSSQRDAEDIKKQPFYKDMKWDSLLHRK
LKAPFVPTVKHAEDVSNFDVEFTSEEPVLTPPRERKTLSTADQHMFSGFD
YVANWC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042721XLOC_042721Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00068492TCONS_00068492Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR011072HR1_rho-bd
IPR000719Prot_kinase_dom
IPR000961AGC-kinase_C
IPR000008C2_dom
IPR017892Pkinase_C
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO:0006468protein phosphorylation
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004674protein serine/threonine kinase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007165 signal transduction
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 94..114
NoneNo IPR availableCOILSCoilCoilcoord: 273..293
NoneNo IPR availableGENE3D1.10.510.10coord: 803..1008
e-value: 3.1E-62
score: 208.7
NoneNo IPR availableGENE3D1.10.287.160coord: 37..115
e-value: 7.2E-13
score: 48.1
NoneNo IPR availableGENE3D1.10.287.160coord: 233..304
e-value: 1.4E-16
score: 59.7
coord: 151..221
e-value: 6.7E-18
score: 63.9
NoneNo IPR availableGENE3D3.30.200.20coord: 556..802
e-value: 1.3E-20
score: 72.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..48
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 524..724
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 213..233
NoneNo IPR availableCDDcd11622HR1_PKN_1coord: 53..115
e-value: 2.73608E-24
score: 97.3366
NoneNo IPR availableCDDcd05589STKc_PKNcoord: 729..1054
e-value: 0.0
score: 716.002
NoneNo IPR availableCDDcd11623HR1_PKN_2coord: 152..218
e-value: 1.7303E-27
score: 106.548
IPR011072HR1 rho-binding repeatSMARTSM00742hr1_7coord: 55..118
e-value: 5.1E-15
score: 65.9
coord: 153..221
e-value: 7.9E-13
score: 58.6
coord: 238..304
e-value: 1.5E-15
score: 67.7
IPR011072HR1 rho-binding repeatPFAMPF02185HR1coord: 239..299
e-value: 2.3E-13
score: 49.9
coord: 58..114
e-value: 4.6E-13
score: 49.0
coord: 154..220
e-value: 5.1E-16
score: 58.4
IPR011072HR1 rho-binding repeatSUPERFAMILY46585HR1 repeatcoord: 53..114
IPR011072HR1 rho-binding repeatSUPERFAMILY46585HR1 repeatcoord: 153..217
IPR011072HR1 rho-binding repeatSUPERFAMILY46585HR1 repeatcoord: 234..303
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 729..988
e-value: 2.1E-93
score: 326.3
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 730..987
e-value: 1.4E-61
score: 208.1
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 729..988
score: 47.255
IPR000961AGC-kinase, C-terminalSMARTSM00133pkinase_C_6coord: 989..1053
e-value: 2.4E-18
score: 77.0
IPR000961AGC-kinase, C-terminalPROSITEPS51285AGC_KINASE_CTERcoord: 989..1056
score: 17.378
IPR000008C2 domainSMARTSM00239C2_3ccoord: 333..461
e-value: 9.5E-4
score: 28.5
IPR000008C2 domainGENE3D2.60.40.150coord: 321..479
e-value: 4.9E-10
score: 39.0
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 388..478
IPR017892Protein kinase, C-terminalPFAMPF00433Pkinase_Ccoord: 1009..1051
e-value: 8.3E-11
score: 42.3
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 735..758
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 850..862
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 726..1043

Blast
[Close]
BLAST of TCONS_00068492-protein vs. Swiss-Prot (Human)
Match: PKN2 (Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 254/340 (74.71%), Postives = 298/340 (87.65%), Query Frame = 0 
Query:  717 RRSRSLTMSVDQFRHISVLGRGHFGKVLLAEYKTTKELFAIKALKKGDIIFRDEVESLMSEKRIFEAANCVRHPFLVNLFACFQTKDHVCFVMEYAPGGDLMMHIHEEVFSEPRTMFYSGCVILGLQYLHDHEIVYRDLKLDNLLLDAEGYVKIADFGLCKEGMGFGQKTGTFCGTPEFLAPEVLTETSYTRSVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSNDSIALMRRLLRKNPDRRLGSSQRDAEDIKKQPFYKDMKWDSLLHRKLKAPFVPTVKHAEDVSNFDVEFTSEEPVLTPPRERKTLSTADQHMFSGFDYVANWC 1056
            R  +    ++  FR  +VLGRGHFGKVLLAEYK T E+FAIKALKKGDI+ RDEV+SLM EKRIFE  N VRHPFLVNLFACFQTK+HVCFVMEYA GGDLMMHIH +VFSEPR +FY+ CV+LGLQYLH+H+IVYRDLKLDNLLLD EG+VKIADFGLCKEGMG+G +T TFCGTPEFLAPEVLTETSYTR+VDWWGLGVLI+EMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLS ++I++MRRLLR+NP+RRLG+S++DAED+KK PF++ + W +L+ +K+K PF+PT++  EDVSNFD EFTSE P+LTPPRE + LS  +Q MF  FDY+A+WC
Sbjct:  645 RSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADWC 984

HSP 2 Score: 392.889 bits (1008), Expect = 3.935e-120
Identity = 237/513 (46.20%), Postives = 320/513 (62.38%), Query Frame = 0 
Query:   53 VDTLRDTIKLEIRRELKIKEGAENLRKVSTDKRTLAQCQQAIKASSQKLDELHDHLQDLNAHISEEIVMASGAGDPGKEILSPQKSMIAYKEDITDHYGNNRMASLEKQLAIEMKVKQGAENMLQMLQGKDSKSKKMIAEAEQMLADSKVKIDAIKMSILREQQSEKNTPETPNNRASLHEKSLEHRVDDIRHHIDIETRVAEGARNMLKHFLINS----DKKGINEAEKTLVEATNKLDLLHMSLERRIAEI--NPAAAQVGIYNEKLL---PSPKSRQRL-----------KAAAVTGKLEVKVLGAEHLLESVPNRDPRKSNTIVASPD-------NKF--RLSKRMSTSTYNSKTTDDSCLSDICAVLKLDNVDVGHSKWKSKEAHCWNETFNISLDKARELEIGVYYRDYRSLCGITFLKLVDFLDNQRHELKLSLEPVGTLRCEVTFFNPLVNRRPRLQRQKQLFPKAKGKHFLRAGDMNTNIATWARLLKRAAPPSSQS--FSPNA 534
            +D ++D IK EIR+ELKIKEGAENLRKV+TDK++LA     +K S++KL+ELH  LQ+LNAHI           DP ++I    ++      D      NNR+ +L+KQL IE+KVKQGAENM+QM     SK +K+   A+Q+L DSK KI+ I+M IL+  Q    T E   + A      LE R++++RHH  IE  VAEGA+N++K  L+ S    D+K ++EA+    E++ KLDLL  SLE+R+ E+  N   +++ I    L+   P+   RQ +           K AA+TG LEV+++G + +LE+VP R      T VA P        + F  R SK  S S+ N   TDD   +D+CAVLKLDN  VG + WK      W++ F + LD++RELEI VY+RD+RSLC + FL+L DFLDNQRH + L LEP GTL  EVTFFNP++ RRP+LQRQK++F K +GK FLRA  MN NIATW RL++RA P  + S  FSP A
Sbjct:   45 LDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIV--------VSDP-EDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQ----TNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMK--LLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGR---SKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLS-NDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQA 538
The following BLAST results are available for this feature:
BLAST of TCONS_00068492-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PKN23.935e-12074.71Serine/threonine-protein kinase N2 OS=Homo sapiens... [more]
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