TCONS_00012693-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012693-protein
Unique NameTCONS_00012693-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length865

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012693-protein ID=TCONS_00012693-protein|Name=TCONS_00012693-protein|organism=Clytia hemisphaerica|type=polypeptide|length=865bp
MKTVLMVAEKPSLAQSIAKILSNGSSSQRKGVSPSCAIHEFQGSFKGENV
FFKMTSVCGHVMALNFSGAFNNWDTCDPIELFQAKTIKKESMPNLNICRH
LQKEGKAIDYLVLWLDCDKEGENICFEVIDIVKPIMKNSQNIFRAKFSAI
TDKDIKQALNTVGKPNKDESMSVDARQELDLRVGCAFTRFQTRYFQGKYG
NLDSSLISYGPCQTPTLGFCVERHDQIQTFKPEIYWRILIKTKSGMQLDW
QRGRIFDKDVALAFHDRMKNEKPQSVKVESVKEKEKAKQRPQALNTVELL
RVASARLGIGPQQTMQIAERLYIQGYISYPRTETNQYHDNYNLKEQVVKQ
KASGVWGGYINKLLNEKGGIQKPRKGQDCGDHPPITPMRVASEGDLGGDT
WRIYSYIVRHFIATVSGDCKYLLCSVLFQLGTESFSCEGRTIIDPGFTEI
LDTNQTEDLNERIPKVEKNQILEIEQILLQERHTTAPEYLSEAELILLME
KHGIGTDASIPTHINNICQRNYVTVTNGRRLVPNPLGIVLVHGYQKIDEQ
LVFPTIRSSVEKQLNLIAQGRACFEDVLSFYVDIFEDKFEFFSKNIQNMD
DLFECSFTKLSETGKPFSKCGKCRRYMKLVEAKPARLHCSTCNETYSVPQ
NGMIKLYQELKCPLDDFEILLWSRHGASKTYSFCPNCYTNPTLEKMEKNL
GCNQCLHPTCKHSALQLGVGPCTACEDGRLILEPFNAPKWILSCNSPKCS
DRYSLCKGAQSVKVKDEVCKCGRKILDVSYKDKAALSGCMACDTAMANLV
NFVAPDGRHSGSRGGSRGGGRGSNRGGRGGGRGGKGRRGGGGRQKDDYVQ
SHPNKNTNLADFIKF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007128XLOC_007128Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012693TCONS_00012693Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013497Topo_IA_cen
IPR003601Topo_IA_2
IPR003602Topo_IA_DNA-bd_dom
IPR006171TOPRIM_domain
IPR013825Topo_IA_cen_sub2
IPR034144TOPRIM_TopoIII
IPR023405Topo_IA_core_domain
Vocabulary: Molecular Function
TermDefinition
GO:0003916DNA topoisomerase activity
GO:0003677DNA binding
Vocabulary: Biological Process
TermDefinition
GO:0006265DNA topological change
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006265 DNA topological change
molecular_function GO:0003677 DNA binding
molecular_function GO:0003916 DNA topoisomerase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013497DNA topoisomerase, type IA, centralPRINTSPR00417PRTPISMRASEIcoord: 324..333
score: 51.04
coord: 111..124
score: 46.95
coord: 207..225
score: 37.1
coord: 503..517
score: 31.84
coord: 403..419
score: 26.98
IPR013497DNA topoisomerase, type IA, centralPFAMPF01131Topoisom_baccoord: 165..578
e-value: 1.1E-111
score: 373.7
IPR013497DNA topoisomerase, type IA, centralCDDcd00186TOP1Accoord: 168..587
e-value: 1.21971E-124
score: 382.338
IPR003601DNA topoisomerase, type IA, domain 2SMARTSM00436topIban2coord: 141..237
e-value: 6.8E-35
score: 131.9
IPR003602DNA topoisomerase, type IA, DNA-binding domainSMARTSM00437topIaneu2coord: 282..541
e-value: 3.2E-80
score: 282.5
IPR006171TOPRIM domainSMARTSM00493toprim5coord: 3..137
e-value: 5.9E-22
score: 88.9
IPR006171TOPRIM domainPFAMPF01751Toprimcoord: 4..150
e-value: 4.3E-18
score: 65.3
IPR006171TOPRIM domainPROSITEPS50880TOPRIMcoord: 3..151
score: 16.014
NoneNo IPR availableGENE3D1.10.460.10coord: 481..601
e-value: 3.0E-18
score: 65.6
coord: 172..350
e-value: 8.8E-39
score: 132.5
NoneNo IPR availableGENE3D3.40.50.140coord: 1..170
e-value: 2.3E-51
score: 173.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 806..857
IPR013825DNA topoisomerase, type IA, central region, subdomain 2GENE3D2.70.20.10coord: 365..480
e-value: 5.3E-19
score: 68.1
IPR034144DNA topoisomerase 3-like, TOPRIM domainCDDcd03362TOPRIM_TopoIA_TopoIIIcoord: 3..160
e-value: 1.54836E-45
score: 160.091
IPR023405DNA topoisomerase, type IA, core domainSUPERFAMILY56712Prokaryotic type I DNA topoisomerasecoord: 3..24
coord: 52..629

Blast
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BLAST of TCONS_00012693-protein vs. Swiss-Prot (Human)
Match: TOP3B (DNA topoisomerase 3-beta-1 OS=Homo sapiens GN=TOP3B PE=1 SV=1)

HSP 1 Score: 985.712 bits (2547), Expect = 0.000e+0
Identity = 468/820 (57.07%), Postives = 595/820 (72.56%), Query Frame = 0 
Query:    1 MKTVLMVAEKPSLAQSIAKILSNGSSSQRKGVSPSCAIHEFQGSFKGENVFFKMTSVCGHVMALNFSGAFNNWDTCDPIELF-QAKTIKKESMPNLNICRHLQKEGKAIDYLVLWLDCDKEGENICFEVIDIVKPIMKNS----QNIFRAKFSAITDKDIKQALNTVGKPNKDESMSVDARQELDLRVGCAFTRFQTRYFQGKYGNLDSSLISYGPCQTPTLGFCVERHDQIQTFKPEIYWRILIKTKS----GMQLDWQRGRIFDKDVALAFHDRMKNEKPQSVKVESVKEKEKAKQRPQALNTVELLRVASARLGIGPQQTMQIAERLYIQGYISYPRTETNQYHDNYNLKEQVVKQKASGVWGGYINKLLNEKGGIQKPRKGQDCGDHPPITPMRVASEGDLGGDTWRIYSYIVRHFIATVSGDCKYLLCSVLFQLGTESFSCEGRTIIDPGFTEILDTNQTEDLNERIPKVEKNQILEIEQILLQERHTTAPEYLSEAELILLMEKHGIGTDASIPTHINNICQRNYVTVTNGRRLVPNPLGIVLVHGYQKIDEQLVFPTIRSSVEKQLNLIAQGRACFEDVLSFYVDIFEDKFEFFSKNIQNMDDLFECSFTKLSETGKPFSKCGKCRRYMKLVEAKPARLHCSTCNETYSVPQNGMIKLYQELKCPLDDFEILLWSRHGASKTYSFCPNCYTNPTLEKMEKNLGCNQCLHPTCKHSALQLGVGPCTACEDGRLILEPFNAPKWILSCNSPKCSDRYSLCKGAQSVKVKDEVCK-CGRKILDVSYK--------DKAALSGCMACDTAMANLVNF 802
            MKTVLMVAEKPSLAQSIAKILS GS S  KG++ +C++HE+ G+F G+ V FKMTSVCGHVM L+F G +N WD  DP ELF QA T KKE+ P LN+ + LQ EG+  DY+VLWLDCDKEGENICFEV+D V P+M  +    + +FRA+FS+ITD DI  A+  +G+P+ +E++SVDARQELDLR+GCAFTRFQT+YFQGKYG+LDSSLIS+GPCQTPTLGFCVERHD+IQ+FKPE YW +  K  +     + LDW R R+FD+++A  F +  K EK    +VE+   KEKAKQRP ALNTVE+LRVAS+ LG+GPQ  MQ AERLY QGYISYPRTET  Y +N++LK  + +Q     W   + +LL E  GI +PRKG D GDHPPITPM+ A+E +LGGD WR+Y YI RHFIATVS DCKYL  ++ F++G E F+C G+T++ PGFTE++   Q+  L E +P  ++     + ++ + E+ T  P+YL+EAELI LMEKHGIGTDASIP HINNICQRNYVTV +GRRL P  LGIVLVHGY KID +LV PTIRS+VEKQLNLIAQG+A +  VL   +D+F+ KF +F  +I  MD+L E SF+ L+ TGKP S+CGKC R+MK ++AKP+RLHCS C+ETY++PQNG IKLY+EL+CPLDDFE++LWS     K+Y  CP CY +P    M+K +GCN+C HP+C+HS   LG+G C  CE G L+L+P + PKW ++CN  KC+      + A  V+V  + C  C   +LDV +         D+    GC+ CD     LV  
Sbjct:    1 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEK--EAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAE--GINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPW-QSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACN--KCNVVAHCFENAHRVRVSADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVEL 813
The following BLAST results are available for this feature:
BLAST of TCONS_00012693-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TOP3B0.000e+057.07DNA topoisomerase 3-beta-1 OS=Homo sapiens GN=TOP3... [more]
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