TCONS_00021623-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00021623-protein
Unique NameTCONS_00021623-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length457

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00021623-protein ID=TCONS_00021623-protein|Name=TCONS_00021623-protein|organism=Clytia hemisphaerica|type=polypeptide|length=457bp
MEQEINNVGIKYIELYFPSQYVSQKKLEKYDQVSPGKYTIGLGQQKMGFC
GDQEDIHSLSLTVLKNLLEKNKINPKDVGRLEVGTETLIDKSKSVKTVLM
QLFEESGNSDIEGLDTTNACFGGTGALFNAINWIESSSYDGRLAIVIIAD
IAVYAEGNARCTGGAGAVALAIAPNAPLVFDTKLRALHMAHQYDFYKPDM
HSEYPTINGQLSLKCYLSAVDTCYQLYGQKFNKKFGFSEAFTMKNLDYMV
FHTPYCKIVQKSVGRCILNDFIHSSSEDSCFENLTKYRGVSLEDTYENAS
LFKEIERACVEASKDVFNEKTMPSLQIATNVGNMYSPSLYSSLCSLLCNK
SMDDLLEKRIAFFSYGSGLASAMFSLKVTDKRDELEPLIRVVMDCYKHLD
QRREIEPQDFVKTLELREKRYNAKSYSPESPVADLFPGTYYLSNVDDKFR
RTYERKT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012120XLOC_012120Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00021623TCONS_00021623Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR010122HMG_CoA_synthase_euk
IPR016039Thiolase-like
IPR013528HMG_CoA_synth_N
IPR013746HMG_CoA_synt_C_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004421hydroxymethylglutaryl-CoA synthase activity
GO:0003824catalytic activity
Vocabulary: Biological Process
TermDefinition
GO:0008299isoprenoid biosynthetic process
GO:0008152metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008299 isoprenoid biosynthetic process
biological_process GO:0008152 metabolic process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004421 hydroxymethylglutaryl-CoA synthase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR010122Hydroxymethylglutaryl-CoA synthase, eukaryoticTIGRFAMTIGR01833TIGR01833coord: 6..456
e-value: 3.6E-200
score: 663.8
IPR016039Thiolase-likeGENE3D3.40.47.10coord: 1..189
e-value: 2.5E-9
score: 36.5
IPR016039Thiolase-likeGENE3D3.40.47.10coord: 190..379
e-value: 2.7E-59
score: 199.5
IPR016039Thiolase-likeSUPERFAMILY53901Thiolase-likecoord: 7..175
IPR016039Thiolase-likeSUPERFAMILY53901Thiolase-likecoord: 307..455
coord: 178..267
IPR013528Hydroxymethylglutaryl-coenzyme A synthase, N-terminalPFAMPF01154HMG_CoA_synt_Ncoord: 6..177
e-value: 8.1E-87
score: 289.5
IPR013746Hydroxymethylglutaryl-coenzyme A synthase C-terminal domainPFAMPF08540HMG_CoA_synt_Ccoord: 178..456
e-value: 2.7E-97
score: 325.7
NoneNo IPR availableCDDcd00827init_cond_enzymescoord: 7..376
e-value: 3.09695E-65
score: 213.834

Blast
[Close]
BLAST of TCONS_00021623-protein vs. Swiss-Prot (Human)
Match: HMCS1 (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens GN=HMGCS1 PE=1 SV=2)

HSP 1 Score: 508.064 bits (1307), Expect = 6.875e-178
Identity = 247/458 (53.93%), Postives = 331/458 (72.27%), Query Frame = 0 
Query:    7 NVGIKYIELYFPSQYVSQKKLEKYDQVSPGKYTIGLGQQKMGFCGDQEDIHSLSLTVLKNLLEKNKINPKDVGRLEVGTETLIDKSKSVKTVLMQLFEESGNSDIEGLDTTNACFGGTGALFNAINWIESSSYDGRLAIVIIADIAVYAEGNARCTGGAGAVALAIAPNAPLVFDTKLRALHMAHQYDFYKPDMHSEYPTINGQLSLKCYLSAVDTCYQLYGQKFNKKF---GFSEAFTMKNLDYMVFHTPYCKIVQKSVGRCILNDFIHSSSED--SCFENLTKYRGVSLEDTYENASLFKEIERACVEASKDVFNEKTMPSLQIATNVGNMYSPSLYSSLCSLLCNKSMDDLLEKRIAFFSYGSGLASAMFSLKVTDKR---DELEPLIRVVMDCYKHLDQRREIEPQDFVKTLELREKRYNAKSYSPESPVADLFPGTYYLSNVDDKFRRTYERK 456
            +VGI  +E+YFPSQYV Q +LEKYD V  GKYTIGLGQ KMGFC D+EDI+SL +TV++NL+E+N ++   +GRLEVGTET+IDKSKSVKT LMQLFEESGN+DIEG+DTTNAC+GGT A+FNA+NWIESSS+DGR A+V+  DIAVYA GNAR TGG GAVAL I PNAPL+F+  LR  HM H YDFYKPDM SEYP ++G+LS++CYLSA+D CY +Y +K + ++   G  + FT+ +  +M+FH+PYCK+VQKS+ R +LNDF++  + D  S +  L  +  V LEDTY +    +++E+A ++AS ++F++KT  SL ++   GNMY+ S+Y SL S+L   S   L  KRI  FSYGSGLA+ ++SLKVT        L+ +   + D    LD R  + P  F + ++LRE  ++  +Y P+  +  LF GT+YL  VD+K RRTY R+
Sbjct:   16 DVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFD----RDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARR 469
The following BLAST results are available for this feature:
BLAST of TCONS_00021623-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HMCS16.875e-17853.93Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS... [more]
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